INT98208

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Context Info
Confidence 0.08
First Reported 2001
Last Reported 2009
Negated 1
Speculated 2
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.14
Pain Relevance 0.63

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Vwf) cell adhesion (Vwf) endoplasmic reticulum (Vwf)
proteinaceous extracellular matrix (Vwf)
Anatomy Link Frequency
endothelium 1
Vwf (Mus musculus)
Pain Link Frequency Relevance Heat
aspirin 10 100.00 Very High Very High Very High
metalloproteinase 2 98.00 Very High Very High Very High
cINOD 2 94.72 High High
cva 4 90.60 High High
cOX1 1 82.00 Quite High
Restless leg syndrome 2 50.00 Quite Low
Angina 2 50.00 Quite Low
Inflammation 1 5.00 Very Low Very Low Very Low
Inflammatory marker 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 1 100.00 Very High Very High Very High
Hemorrhage 10 98.08 Very High Very High Very High
INFLAMMATION 3 94.48 High High
Cv General 3 Under Development 6 90.60 High High
Hypothermia 4 80.84 Quite High
Cardiovascular Disease 1 79.96 Quite High
Injury 43 58.00 Quite High
Coagulation Disorder 28 54.16 Quite High
Increased Venous Pressure Under Development 2 50.00 Quite Low
Hemorrhagic Shock 1 44.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we investigated the effects of aspirin on the von Willebrand Factor receptor complex glycoprotein (GP) Ib-V-IX, whose lack or dysfunction causes bleeding in patients.
Spec (investigated) Regulation (effects) of von Willebrand Factor receptor complex glycoprotein associated with aspirin and hemorrhage
1) Confidence 0.08 Published 2005 Journal J. Biol. Chem. Section Abstract Doc Link 16179345 Disease Relevance 0.36 Pain Relevance 0.49
RESULTS: there was no significant change in vWF.
Neg (no) Regulation (change) of vWF
2) Confidence 0.05 Published 2001 Journal Eur J Vasc Endovasc Surg Section Body Doc Link 11563891 Disease Relevance 0 Pain Relevance 0
Thirdly, the endothelial contribution to haemostasis is not displayed in VHA and therefore, conditions affecting the endothelium such as von Willebrand disease (vWD, quantitative or qualitative defects in vWF and, hence inability of the platelets to adhere to the endothelium), cannot be investigated.
Spec (investigated) Regulation (affecting) of vWD in endothelium associated with disease
3) Confidence 0.03 Published 2009 Journal Scand J Trauma Resusc Emerg Med Section Body Doc Link PMC2758824 Disease Relevance 0.63 Pain Relevance 0.13
RESULTS: The mean levels of IL-6 before stenting were significaNtly higher in unstable than in stable angina patients (p = 0.002), whereas baseline values of vWf showed no difference between the two groups.
Regulation (values) of vWf
4) Confidence 0.03 Published 2002 Journal Ital Heart J Section Body Doc Link 12478817 Disease Relevance 0.15 Pain Relevance 0

General Comments

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