INT9824

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Context Info
Confidence 0.16
First Reported 1992
Last Reported 1992
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.64

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signal transduction (Agtr2) plasma membrane (Agtr2) transcription factor binding (Agtr2)
cytoplasm (Bcl2a1a) signal transducer activity (Agtr2)
Agtr2 (Mus musculus)
Bcl2a1a (Mus musculus)
Pain Link Frequency Relevance Heat
adenocard 11 99.48 Very High Very High Very High
Lasting pain 1 92.48 High High
agonist 1 89.08 High High
intrathecal 1 83.60 Quite High
Antinociceptive 3 81.96 Quite High
Pain 1 77.36 Quite High
nociceptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Pain 2 92.48 High High
Hyperalgesia 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The drugs chosen were, R-phenylisopropyl-adenosine (R-PIA) with high affinity for the A1 receptor, N-ethylcarboxamide-adenosine (NECA) with almost equal affinity for the A1 and A2 receptor and 2-(2-aminoethylamino)-carbonylethylphenylethylamino-adenosin e (APEC) with high affinity for the A2 receptor.
A2 receptor Binding (affinity) of A1 associated with adenocard
1) Confidence 0.16 Published 1992 Journal Pharmacol. Toxicol. Section Abstract Doc Link 1438021 Disease Relevance 0.24 Pain Relevance 0.64

General Comments

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