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Context Info
Confidence 0.07
First Reported 2001
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.54
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PDE2A) signal transduction (PDE2A) Golgi apparatus (PDE2A)
endoplasmic reticulum (PDE2A) plasma membrane (PDE2A) nucleus (PDE2A)
PDE2A (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 1 87.08 High High
cINOD 2 69.36 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 7 89.84 High High
Death 2 89.48 High High
Cancer 6 87.20 High High
Colon Cancer 6 82.36 Quite High
INFLAMMATION 2 69.12 Quite High
Solid Tumor 1 61.96 Quite High
Pancreatic Cancer 1 61.92 Quite High
Suicidal Behaviour 1 27.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further, although exisulind induced expression of PKG Ibeta, it did not elevate intracellular cGMP and its efficacy was not altered by inhibition or activation of PKG I.
Regulation (efficacy) of cGMP
1) Confidence 0.07 Published 2006 Journal Mol. Cancer Ther. Section Abstract Doc Link 16731751 Disease Relevance 0.73 Pain Relevance 0.10
Any single type of cell expresses a limited number of PDE-isoforms in order to regulate cGMP or cAMP levels.
Regulation (regulate) of cGMP
2) Confidence 0.03 Published 2001 Journal Curr Opin Investig Drugs Section Abstract Doc Link 11569947 Disease Relevance 0.82 Pain Relevance 0.07

General Comments

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