INT98409

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Context Info
Confidence 0.08
First Reported 2001
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.97
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
cranial nerve 1
Rf (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 130 99.84 Very High Very High Very High
imagery 6 93.24 High High
Pain 6 82.20 Quite High
Inflammation 15 79.80 Quite High
Arthritis 31 74.92 Quite High
Rheumatism 7 5.00 Very Low Very Low Very Low
Infliximab 6 5.00 Very Low Very Low Very Low
Etanercept 3 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 135 99.84 Very High Very High Very High
Cancer 1 99.40 Very High Very High Very High
Viral Infection 1 99.22 Very High Very High Very High
Cryoglobulinemia 1 98.80 Very High Very High Very High
Meningitis 8 98.72 Very High Very High Very High
Syndrome 9 98.26 Very High Very High Very High
Systemic Lupus Erythematosus 4 97.76 Very High Very High Very High
Hypopituitarism 6 97.04 Very High Very High Very High
Immune System Diseases 5 96.86 Very High Very High Very High
Cranial Neuropathy 4 95.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This is the first report of a patient presenting with rheumatoid factor (RF) positive hypertrophic cranial pachymeningitis (HCP) in association with hypopituitarism and multiple cranial nerve palsies.
RF Binding (presenting) of in cranial nerve associated with cranial neuropathy, meningitis and hypopituitarism
1) Confidence 0.08 Published 2001 Journal Intern. Med. Section Abstract Doc Link 11579967 Disease Relevance 0.92 Pain Relevance 0.14
Although the exact mechanism of HCP has not been clearly elucidated, the present case suggests an autoimmune mechanism associated with RF.
RF Binding (associated) of associated with meningitis
2) Confidence 0.07 Published 2001 Journal Intern. Med. Section Abstract Doc Link 11579967 Disease Relevance 0.92 Pain Relevance 0.21
Since many rheumatic or immune diseases, including systemic lupus erythematosus (SLE), Sjogren’s syndrome (SS), primary cryoglobulinemia, and viral infection or tumor may develop positive RF, the specificity of RF in RA is apparently lower (4,7–9).
RF Binding (specificity) of associated with cryoglobulinemia, cancer, syndrome, viral infection, rheumatoid arthritis, systemic lupus erythematosus and immune system diseases
3) Confidence 0.01 Published 2007 Journal Biomarker Insights Section Body Doc Link PMC2717818 Disease Relevance 1.57 Pain Relevance 0.35
There was a highly significant association between RF positivity by nephelometry and that by ELISA (odds ratio 44.56, 95% CI 17.98–114.51; P < 0.00001).
RF Binding (association) of
4) Confidence 0.01 Published 2003 Journal Arthritis Res Ther Section Body Doc Link PMC165032 Disease Relevance 0.55 Pain Relevance 0.24

General Comments

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