INT98448

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Context Info
Confidence 0.39
First Reported 2001
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.60
Pain Relevance 1.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) aging (Il6) extracellular region (Il6)
Anatomy Link Frequency
plasma 2
Il6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 18 100.00 Very High Very High Very High
Restless leg syndrome 5 96.96 Very High Very High Very High
Hyperalgesia 7 96.92 Very High Very High Very High
Inflammation 20 94.32 High High
Spinal cord 4 92.48 High High
tolerance 2 79.32 Quite High
imagery 2 16.72 Low Low
agonist 66 5.00 Very Low Very Low Very Low
rheumatoid arthritis 18 5.00 Very Low Very Low Very Low
Arthritis 11 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Osteoporosis 5 98.24 Very High Very High Very High
Increased Venous Pressure Under Development 5 96.96 Very High Very High Very High
Hyperalgesia 7 96.92 Very High Very High Very High
Disorder Of Lipid Metabolism 4 94.84 High High
Necrosis 4 89.72 High High
Neurodegenerative Disease 1 89.24 High High
Dyslipidemia /

Combined Dyslipidemia

1 85.76 High High
Bone Cancer 4 82.44 Quite High
INFLAMMATION 23 75.00 Quite High
Death 4 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Stavudine administration did not affect the plasma concentration of IL-6, CINC-1, adiponectin or lactate.
Neg (not) Regulation (affect) of IL-6 Neg (not) Binding (concentration) of in plasma
1) Confidence 0.39 Published 2009 Journal Neurotoxicology Section Abstract Doc Link 19442827 Disease Relevance 0.87 Pain Relevance 0.91
To determine whether a reduction of IL-6 contributes to the improvement of lipid profiles, we prospectively investigated the effect of cilostazol (n=16, 100 mg, twice daily) on the changes of lipid profiles and on the association with the changes of IL-6 compared with those of pentoxifylline (n=16, 400 mg, bid) in patients with IC.
Spec (investigated) Regulation (effect) of IL-6 Binding (association) of associated with restless leg syndrome
2) Confidence 0.39 Published 2001 Journal Atherosclerosis Section Abstract Doc Link 11583728 Disease Relevance 0.69 Pain Relevance 0.46
ELISA-based TransAm™ kit for NF-IL-6, NF-?
Regulation (ELISA) of IL-6 Binding (kit) of
3) Confidence 0.38 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656246 Disease Relevance 0 Pain Relevance 0.03
This upregulation occurs through cytokine signaling of IL-6, TNF-?
Regulation (signaling) of IL-6 Binding (cytokine) of associated with cytokine
4) Confidence 0.18 Published 2010 Journal Advances in Hematology Section Body Doc Link PMC2905716 Disease Relevance 0.96 Pain Relevance 0.05

General Comments

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