INT98455

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.20
First Reported 2001
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 1.76
Pain Relevance 1.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Src) enzyme binding (Src) cytoplasm (Src)
cell proliferation (Src) cell adhesion (Src) nucleus (Src)
Src (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 50 100.00 Very High Very High Very High
nMDA receptor 21 99.84 Very High Very High Very High
opioid receptor 90 99.12 Very High Very High Very High
depression 32 99.08 Very High Very High Very High
Hippocampus 23 96.92 Very High Very High Very High
Glutamate receptor 11 95.20 Very High Very High Very High
Morphine 80 91.52 High High
analgesia 13 90.80 High High
tolerance 34 89.60 High High
Analgesic 23 86.36 High High
Disease Link Frequency Relevance Heat
Depression 32 99.08 Very High Very High Very High
Cancer 63 97.80 Very High Very High Very High
Adhesions 10 83.64 Quite High
Breast Cancer 22 78.84 Quite High
Anxiety Disorder 29 74.16 Quite High
Urological Neuroanatomy 19 66.36 Quite High
Hypoxia 10 52.40 Quite High
Bordatella Infection 2 51.08 Quite High
Brain Disease 7 50.00 Quite Low
Metastasis 62 49.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, a number of lines of research suggest a role for the FAK and Src kinases in regulation of vascular permeability during tumor cell extravasation, with LOX playing a regulatory role in this process.
Regulation (role) of Src associated with cancer
1) Confidence 0.20 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2680032 Disease Relevance 0.94 Pain Relevance 0
This regulation integrates the positive effects of PI3K, Akt, nNOS, PKC, Src, NMDAR and CaMKII on MOR inhibition.
Regulation (effects) of Src associated with kinase c and opioid receptor
2) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890584 Disease Relevance 0.07 Pain Relevance 0.99
Ins and outs of SRC regulation of NMDA receptors and synaptic plasticity

• John F MacDonald (University of Toronto, Toronto, Canada)

Regulation (regulation) of SRC associated with nmda receptor
3) Confidence 0.12 Published 2006 Journal Mol Pain Section Body Doc Link PMC1769477 Disease Relevance 0.07 Pain Relevance 0.15
Several molecules involved in RP, such as CaMKII, mGluR1, and Src, are also involved in LTD (Ito, 2001; Hansel et al, 2001, 2006; Tsuruno et al, 2008).
Regulation (involved) of Src associated with depression
4) Confidence 0.11 Published 2009 Journal Mol Syst Biol Section Body Doc Link PMC2710870 Disease Relevance 0.63 Pain Relevance 0.28
A high molecular mass (around 220 kDa) form of the alpha(1A) subunit was detected by anti-phosphotyrosine, suggesting a possible target for Src family kinase action.
Spec (possible) Regulation (target) of Src
5) Confidence 0.09 Published 2001 Journal J. Biol. Chem. Section Abstract Doc Link 11583988 Disease Relevance 0.05 Pain Relevance 0.06

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox