INT985
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
GH treatment in adults with GH deficiency has numerous beneficial effects, but most studies have been small. | |||||||||||||||
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Concerning the influence of metabolic and nutritional factors, an impaired somatotropin response to hypoglycaemia and a failure of glucose load to inhibit spontaneous and stimulated GH release are well documented in obese patients; furthermore, drugs able to block lipolysis and thus to lower serum free fatty acids (NEFA) significantly improve somatotropin secretion in obesity. | |||||||||||||||
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The clinical usefulness of liquid human growth hormone (hGH) (Norditropin SimpleXx in the treatment of GH deficiency. | |||||||||||||||
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A physiological decrease in growth hormone (GH) and IGF-I secretion accompanies these changes. | |||||||||||||||
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GH treatment has also been used with encouraging results in adult subjects with isolated or combined GH deficiency. | |||||||||||||||
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GH administration to elderly individuals has produced an decrease in fat mass and an increase in lean body mass, being this finding consistent with the hypothesis that GH deficiency could be a contributing cause to senescent changes in some elderly individuals. | |||||||||||||||
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In the early 1960s, growth hormone (GH) deficiency was treated by intramuscular injection of GH extracted from human pituitary glands. | |||||||||||||||
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The sc and im administration of human GH (hGH) was compared in the therapy of GH deficiency. | |||||||||||||||
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Growth parameters and predictors of growth in short children with and without growth hormone (GH) deficiency treated with human GH: a randomized controlled study. | |||||||||||||||
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In conclusion NLA and enflurane induced a decrease of GH and PRL plasma levels; in both groups the anaesthetic agents, at the dosage used during anaesthesia, blocked the response of these hormones to the surgical stress likely due to a block of the hypothalamic-pituitary response. | |||||||||||||||
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A reduction of the growth hormone (GH) response to the alpha(2) adrenergic agonist clonidine is a neuroendocrine abnormality observed with reasonable consistency among human patients with mood and anxiety disorders. | |||||||||||||||
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It has been used to test for GH deficiency in children, to assess central alpha(2)-adrenoceptor function in adults and to determine the pathophysiological basis and to confirm diagnosis in neurological diseases with autonomic failure. | |||||||||||||||
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One patient and one healthy subject had a GH dose reduction. | |||||||||||||||
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Although she had no overt symptoms of acromegaly, her cardiac function was improved when her GH and IGF-1 levels were reduced as she had less dyspnoea. | |||||||||||||||
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The goals of treatment for acromegaly are to reduce GH levels to <2.5 ng/ml, normalize IGF-1 levels, and/or control tumor mass [6,7]. | |||||||||||||||
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Her GH level was >40 ng/ml and was not suppressed by a standard oral glucose load. | |||||||||||||||
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A significative reduction of GH at 60' and of PRL at 30' was observed in both groups. | |||||||||||||||
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Seventy-four prepubertal patients with documented GH deficiency were randomized to receive sustained release recombinant human GH at either 1.5 mg/kg once monthly or 0.75 mg/kg twice monthly by sc injection in a 6-month open-label study. | |||||||||||||||
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The GH deficiency in adults may have arisen i either childhood or during adult life and these two groups differ with regard to history of disease. | |||||||||||||||
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There were 98 patients with adult-onset and 67 patients with childhood-onset GH deficiency. | |||||||||||||||
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