INT98555

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Context Info
Confidence 0.51
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 1.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Casp8) protein complex (Casp8) cytoplasm (Casp8)
signal transducer activity (Oprm1) cytosol (Casp8) signal transduction (Oprm1)
Anatomy Link Frequency
lymph node 1
Oprm1 (Mus musculus)
Casp8 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 4 100.00 Very High Very High Very High
Morphine 10 99.84 Very High Very High Very High
cytokine 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Apoptosis 3 100.00 Very High Very High Very High
Targeted Disruption 1 73.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our results suggest that low-dose morphine, through the mu-opioid receptor, can induce lymph node lymphocyte apoptosis through the cleavage activity of caspase-3 and caspase-8.
mu-opioid receptor Positive_regulation (induce) of caspase-8 in lymph node associated with opioid receptor, apoptosis and morphine
1) Confidence 0.51 Published 2001 Journal J. Leukoc. Biol. Section Abstract Doc Link 11590188 Disease Relevance 0.36 Pain Relevance 1.02

General Comments

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