INT98567

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Context Info
Confidence 0.40
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 6.10
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Cd4) plasma membrane (Cd4) enzyme binding (Cd4)
Anatomy Link Frequency
T-cell 6
monocytes 2
Cd4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
spastic colon 93 96.00 Very High Very High Very High
Inflammatory marker 1 88.68 High High
cytokine 20 72.40 Quite High
substance P 15 57.60 Quite High
Pain 18 56.48 Quite High
depression 11 55.28 Quite High
Pain score 12 50.96 Quite High
Inflammation 36 50.00 Quite Low
qutenza 4 50.00 Quite Low
Inflammatory response 2 50.00 Quite Low
Disease Link Frequency Relevance Heat
Immune Reconstitution Inflammatory Syndrome 584 98.92 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

95 96.00 Very High Very High Very High
Fungal Infection 56 92.00 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 154 88.96 High High
INFLAMMATION 30 88.36 High High
Depression 13 88.20 High High
Cancer 50 66.00 Quite High
Skin Cancer 26 61.24 Quite High
Pain 31 56.48 Quite High
Anxiety Disorder 8 54.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The median CD4 count was consistently lower in the ?
Negative_regulation (lower) of Gene_expression (count) of CD4
1) Confidence 0.40 Published 2010 Journal AIDS Res Ther Section Body Doc Link PMC3022663 Disease Relevance 0.55 Pain Relevance 0
So were the CD4+/CD8+ ratios in all medicated groups.
Negative_regulation (were) of Gene_expression (ratios) of CD4
2) Confidence 0.34 Published 2007 Journal BMC Cancer Section Body Doc Link PMC1821034 Disease Relevance 0.30 Pain Relevance 0.07
Low baseline CD4+ T-cell count (HR?
Negative_regulation (Low) of Gene_expression (count) of CD4 in T-cell
3) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2895658 Disease Relevance 0.95 Pain Relevance 0
0.17 per additional 10 increase in CD4%; 95% CI: 0.04, 0.69; p<0.001), higher CD4+ percentage on ART (HR?
Negative_regulation (higher) of Gene_expression (percentage) of CD4
4) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2895658 Disease Relevance 1.24 Pain Relevance 0
Low baseline CD4+ T-cell count (HR?
Negative_regulation (baseline) of Gene_expression (count) of CD4 in T-cell
5) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2895658 Disease Relevance 0.95 Pain Relevance 0
0.17 per additional 10 increase in CD4%; 95% CI: 0.04, 0.69; p<0.001), higher CD4+ percentage on ART (HR?
Negative_regulation (0.04) of Gene_expression (percentage) of CD4
6) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2895658 Disease Relevance 1.25 Pain Relevance 0
Postoperative immune function was assessed by measuring the white blood cell (WBC) count, the CD4+ and CD8+ lymphocytes, the CD4+/CD8+/ratio, and the HLA-DR expression of CD14+ monocytes.
Negative_regulation (measuring) of Gene_expression (expression) of CD4 in monocytes
7) Confidence 0.13 Published 2001 Journal Surg Endosc Section Body Doc Link 11591950 Disease Relevance 0.09 Pain Relevance 0
Similar staining but of fewer cells was seen using the CD4 T cell antibody in both groups, and this was not statistically significant (p?
Negative_regulation (using) of Gene_expression (antibody) of CD4 in T cell
8) Confidence 0.09 Published 2008 Journal Gut Section Body Doc Link PMC2564830 Disease Relevance 0.31 Pain Relevance 0.68

General Comments

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