INT98575

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Context Info
Confidence 0.68
First Reported 2001
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.33
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Sele) cell adhesion (Sele) molecular_function (Sele)
cellular_component (Sele)
Anatomy Link Frequency
endothelium 2
Sele (Rattus norvegicus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 7 95.68 Very High Very High Very High
Pain 1 95.64 Very High Very High Very High
cINOD 1 75.80 Quite High
Inflammation 3 71.36 Quite High
Disease Link Frequency Relevance Heat
Adhesions 4 100.00 Very High Very High Very High
Rheumatoid Arthritis 7 95.68 Very High Very High Very High
Pain 1 95.64 Very High Very High Very High
Peripheral Arterial Disease 3 94.40 High High
Atherosclerosis 5 92.32 High High
Stress 3 85.72 High High
INFLAMMATION 3 75.56 Quite High
Disease 2 75.00 Quite High
Cv Unclassified Under Development 2 67.84 Quite High
Atherosclerotic Plaque 1 67.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In fact, immune complexes fixing C1q bind to endothelial receptors, thus triggering an upregulation of adhesion molecules, such as E-selectin and intercellular and vascular cell adhesion molecules 1, on the endothelium surface.
Positive_regulation (triggering) of Positive_regulation (upregulation) of E-selectin in endothelium associated with adhesions
1) Confidence 0.68 Published 2002 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 12114307 Disease Relevance 1.47 Pain Relevance 0.41
Serum levels of E-selectin, P-selectin, L-selectin, intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-I (VCAM-1) were measured at rest and after the performance of a treadmill walking test (treadmill speed 3.5 km h(-1), inclination 12%) in the untreated condition, and again after treatment with LPC.
Positive_regulation (measured) of Positive_regulation (levels) of E-selectin associated with adhesions
2) Confidence 0.03 Published 2001 Journal Pharmacol. Res. Section Abstract Doc Link 11592865 Disease Relevance 0.86 Pain Relevance 0.10

General Comments

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