INT98580

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.49
First Reported 2001
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 11
Total Number 11
Disease Relevance 10.16
Pain Relevance 1.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (CADM1) cell adhesion (CADM1) plasma membrane (CADM1)
Anatomy Link Frequency
monocyte 4
coronary artery 1
CADM1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 644 100.00 Very High Very High Very High
cytokine 606 99.44 Very High Very High Very High
cva 54 98.80 Very High Very High Very High
Pain 1 95.64 Very High Very High Very High
cINOD 2 75.00 Quite High
aspirin 5 74.48 Quite High
Angina 6 16.20 Low Low
Inflammatory response 40 5.00 Very Low Very Low Very Low
Bioavailability 9 5.00 Very Low Very Low Very Low
depression 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 693 100.00 Very High Very High Very High
Adhesions 84 100.00 Very High Very High Very High
Diabetes Mellitus 9 99.82 Very High Very High Very High
Carcinoma 95 99.80 Very High Very High Very High
Cv General 3 Under Development 58 98.80 Very High Very High Very High
Atherosclerosis 45 98.52 Very High Very High Very High
Coronary Vasospasm 7 96.36 Very High Very High Very High
Pain 1 95.64 Very High Very High Very High
Renal Cancer 18 94.48 High High
Peripheral Arterial Disease 3 94.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In mice, monocular deprivation increases levels of SNAP-25 and SynCAM (synaptic cell adhesion molecule) transcripts [78], both of which are required for synaptogenesis [79-81].
Positive_regulation (increases) of synaptic cell adhesion molecule associated with adhesions
1) Confidence 0.49 Published 2011 Journal Behav Brain Funct Section Body Doc Link PMC3023691 Disease Relevance 0.10 Pain Relevance 0
We detected a small increase in expression of ICAM1 (intercellular adhesion molecule 1) in CC (Fold-change = 1.9, p-value = 0.0081), which was also consistent with the literature [17].
Positive_regulation (increase) of adhesion molecule 1 associated with carcinoma and adhesions
2) Confidence 0.20 Published 2002 Journal BMC Bioinformatics Section Body Doc Link PMC130042 Disease Relevance 1.17 Pain Relevance 0
B, a regulator of several genes implicated in atherogenesis, such as genes coding for intracellular adhesion molecule-1 (ICAM-1) and vascular cellular adhesion molecule-1 (VCAM-1) and cytokines. ?
Positive_regulation (vascular) of adhesion molecule-1 associated with atherosclerosis, adhesions and cytokine
3) Confidence 0.18 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2747395 Disease Relevance 1.63 Pain Relevance 0.29
B, a regulator of several genes implicated in atherogenesis, such as genes coding for intracellular adhesion molecule-1 (ICAM-1) and vascular cellular adhesion molecule-1 (VCAM-1) and cytokines. ?
Positive_regulation (cellular) of adhesion molecule-1 associated with atherosclerosis, adhesions and cytokine
4) Confidence 0.18 Published 2009 Journal Vascular Health and Risk Management Section Body Doc Link PMC2747395 Disease Relevance 1.62 Pain Relevance 0.29
Circulating plasma levels of P-selectin, E-selectin, and intercellular cell adhesion molecule-1 were elevated in patients with vasospastic angina, indicating an association of endothelial damage and inflammatory reaction with coronary vasospasm.55)56) Hung et al.57) prospectively investigated the association of high-sensitivity C-reactive protein (CRP), a sensitive marker of inflammation, with coronary vasospasm and no hemodynamically significant coronary artery disease in a sample of 428 patients who underwent coronary angiography.
Positive_regulation (elevated) of adhesion molecule-1 in coronary artery associated with coronary artery disease, inflammation, cva, coronary vasospasm and adhesions
5) Confidence 0.07 Published 2009 Journal Korean Circulation Journal Section Body Doc Link PMC2801457 Disease Relevance 1.40 Pain Relevance 0.47
These include a ten-fold upregulation of adhesion molecules such as E- selectin by TNF [167], CD36 [122], intercellular adhesion molecule-1 (ICAM-1 CD54) and vascular cell adhesion molecule-1 (VCAM-1 CD106) [168] and, with implications for the observed accumulation of monocytes, monocyte chemotactic protein-1 (MCP-1) [169].
Positive_regulation (upregulation) of adhesion molecule-1 in monocyte associated with adhesions
6) Confidence 0.03 Published 2006 Journal Malar J Section Body Doc Link PMC1629020 Disease Relevance 0.54 Pain Relevance 0.12
These include a ten-fold upregulation of adhesion molecules such as E- selectin by TNF [167], CD36 [122], intercellular adhesion molecule-1 (ICAM-1 CD54) and vascular cell adhesion molecule-1 (VCAM-1 CD106) [168] and, with implications for the observed accumulation of monocytes, monocyte chemotactic protein-1 (MCP-1) [169].
Positive_regulation (upregulation) of adhesion molecule-1 in monocyte associated with adhesions
7) Confidence 0.03 Published 2006 Journal Malar J Section Body Doc Link PMC1629020 Disease Relevance 0.55 Pain Relevance 0.12
Sulfasalazine (also as a representative of the salicylates) inhibited the diabetes-induced upregulation of several inflammatory gene products, which are regulated by NF-kappaB, including vascular cell adhesion molecule, intracellular adhesion molecule-1, inducible nitric oxide synthase, and cyclooxygenase-2 in whole-retinal lysate.
Positive_regulation (upregulation) of adhesion molecule-1 associated with inflammation, diabetes mellitus and adhesions
8) Confidence 0.02 Published 2007 Journal Diabetes Section Abstract Doc Link 17259377 Disease Relevance 1.21 Pain Relevance 0.16
These include a ten-fold upregulation of adhesion molecules such as E- selectin by TNF [167], CD36 [122], intercellular adhesion molecule-1 (ICAM-1 CD54) and vascular cell adhesion molecule-1 (VCAM-1 CD106) [168] and, with implications for the observed accumulation of monocytes, monocyte chemotactic protein-1 (MCP-1) [169].
Positive_regulation (upregulation) of adhesion molecule-1 in monocytes associated with adhesions
9) Confidence 0.01 Published 2006 Journal Malar J Section Body Doc Link PMC1629020 Disease Relevance 0.55 Pain Relevance 0.12
These include a ten-fold upregulation of adhesion molecules such as E- selectin by TNF [167], CD36 [122], intercellular adhesion molecule-1 (ICAM-1 CD54) and vascular cell adhesion molecule-1 (VCAM-1 CD106) [168] and, with implications for the observed accumulation of monocytes, monocyte chemotactic protein-1 (MCP-1) [169].
Positive_regulation (upregulation) of adhesion molecule-1 in monocytes associated with adhesions
10) Confidence 0.01 Published 2006 Journal Malar J Section Body Doc Link PMC1629020 Disease Relevance 0.54 Pain Relevance 0.12
Serum levels of E-selectin, P-selectin, L-selectin, intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-I (VCAM-1) were measured at rest and after the performance of a treadmill walking test (treadmill speed 3.5 km h(-1), inclination 12%) in the untreated condition, and again after treatment with LPC.
Positive_regulation (levels) of adhesion molecule-I associated with adhesions
11) Confidence 0.00 Published 2001 Journal Pharmacol. Res. Section Abstract Doc Link 11592865 Disease Relevance 0.86 Pain Relevance 0.10

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox