INT98671

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Context Info
Confidence 0.00
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (ROS1) cell proliferation (ROS1) extracellular region (Penk)
plasma membrane (ROS1)
Anatomy Link Frequency
astrocytes 2
ROS1 (Homo sapiens)
Penk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 2 100.00 Very High Very High Very High
Neuropeptide 1 100.00 Very High Very High Very High
Enkephalin 2 25.00 Low Low
orphanin 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 1 95.28 Very High Very High Very High
Brain Injury 1 94.00 High High
Stroke 1 92.96 High High
Stress 6 90.96 High High
Hypoxia 1 73.84 Quite High
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study we have demonstrated that reactive oxygen species (ROS) dramatically induce the expression of two neuropeptide genes, the opioid proenkephalin (pENK) and the opioid-related proorphanin FQ (pOFQ; also known as pronociceptin) in primary astrocytes.
ROS Positive_regulation (induce) of Gene_expression (expression) of opioid proenkephalin in astrocytes associated with neuropeptide and opioid
1) Confidence 0.00 Published 2001 Journal J. Neurochem. Section Abstract Doc Link 11595755 Disease Relevance 0.52 Pain Relevance 0.25

General Comments

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