INT98778

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Context Info
Confidence 0.51
First Reported 2001
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.06
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (DHRS9) endoplasmic reticulum (DHRS9)
Anatomy Link Frequency
brain 2
DHRS9 (Homo sapiens)
Pain Link Frequency Relevance Heat
cerebral cortex 1 86.88 High High
gABA 1 65.36 Quite High
Serotonin 1 60.48 Quite High
Analgesic 1 58.08 Quite High
Dismenorea 1 26.56 Quite Low
depression 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 1 57.52 Quite High
Fatigue 1 28.64 Quite Low
Reprotox - General 1 1 26.56 Quite Low
Depressive Disorder 1 25.00 Low Low
Epilepsy 1 25.00 Low Low
Post-partum Depression 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The presence of the steroidogenic enzymes cytochrome P450(SCC), aromatase, 5alpha-reductase, 3alpha-hydroxysteroid dehydrogenase, and 17beta-hydroxysteroid dehydrogenase in the human brain has now been firmly established by molecular biological and biochemical studies.
Gene_expression (presence) of 3alpha-hydroxysteroid dehydrogenase in brain
1) Confidence 0.51 Published 2003 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 14993041 Disease Relevance 0 Pain Relevance 0.11
As human type 2 3 alpha HSD is expressed in a region-specific fashion in the brain, 3 alpha HP may only be made in specific regions of the brain.
Gene_expression (expressed) of 3 alpha HSD in brain
2) Confidence 0.37 Published 2001 Journal Endocrinology Section Abstract Doc Link 11606426 Disease Relevance 0.06 Pain Relevance 0.06

General Comments

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