INT98814

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Context Info
Confidence 0.27
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.14
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ucn)
Ucn (Mus musculus)
Pain Link Frequency Relevance Heat
qutenza 2 94.28 High High
antagonist 5 91.88 High High
cerebral cortex 3 89.52 High High
amygdala 8 86.16 High High
medulla 4 85.36 High High
Hippocampus 2 74.16 Quite High
Spinal cord 2 28.20 Quite Low
Thalamus 1 25.84 Quite Low
Limbic system 1 24.08 Low Low
cytokine 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Appetite Loss 1 85.60 High High
Targeted Disruption 10 58.48 Quite High
Stress 28 38.88 Quite Low
Diabetes Insipidus 1 10.32 Low Low
Polyuria 1 6.72 Low Low
Hyponatremia 5 5.00 Very Low Very Low Very Low
Anxiety Disorder 4 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Small Cell Lung Cancer 4 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data indicate that intraperitoneal urocortin-induced decrease in feeding is only partly mediated by CRF-R2, whereas urocortin action to delay gastric emptying of a meal involves primarily CRF-R2.
Negative_regulation (decrease) of urocortin-induced
1) Confidence 0.27 Published 2001 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 11641109 Disease Relevance 0.09 Pain Relevance 0.28
In the systemic circulation, CRH and Ucn1 are known to bind CRH-binding protein (CRH-BP), resulting in the inactivation of CRH and Ucn1 (Potter et al. 1991).
Negative_regulation (inactivation) of Ucn1
2) Confidence 0.27 Published 2008 Journal Gene Regulation and Systems Biology Section Body Doc Link PMC2733102 Disease Relevance 0.06 Pain Relevance 0.27

General Comments

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