INT98870

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Context Info
Confidence 0.41
First Reported 2001
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (HSPG2) small molecule metabolic process (HSPG2) extracellular region (HSPG2)
plasma membrane (HSPG2) extracellular matrix organization (HSPG2) lipid metabolic process (HSPG2)
HSPG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 3 97.00 Very High Very High Very High
Opioid 2 92.00 High High
antagonist 10 83.24 Quite High
MU agonist 1 75.00 Quite High
Cannabinoid 8 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bordatella Infection 1 45.36 Quite Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Cough 1 5.00 Very Low Very Low Very Low
Burns 1 5.00 Very Low Very Low Very Low
Pharyngitis 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Toothache 1 5.00 Very Low Very Low Very Low
Acute Monocytic Leukemia 1 5.00 Very Low Very Low Very Low
Snake Bites 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of forskolin-stimulated adenylyl cyclase and phospholipase C beta (PLC beta) activation was measured in each of these cell lines.
Negative_regulation (Inhibition) of Positive_regulation (activation) of PLC
1) Confidence 0.41 Published 2001 Journal Mol. Pharmacol. Section Abstract Doc Link 11641436 Disease Relevance 0 Pain Relevance 0.25
To test whether phospholipase C (PLC) activation is required for the Echinacea-induced increase in [Ca2+]i, the effects of U-73122, a specific PLC inhibitor, and its inactive analog U-73343 were evaluated.
Negative_regulation (inhibitor) of Spec (whether) Positive_regulation (activation) of PLC
2) Confidence 0.06 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3002894 Disease Relevance 0 Pain Relevance 0.12

General Comments

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