INT9888

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Context Info
Confidence 0.51
First Reported 1992
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 4
Disease Relevance 3.34
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Arr3)
Anatomy Link Frequency
paw 2
colon 1
Arr3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 1 99.28 Very High Very High Very High
Inflammation 16 87.60 High High
cINOD 1 86.76 High High
Pain 15 83.64 Quite High
Analgesic 9 75.00 Quite High
COX2 6 25.00 Low Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 15 99.64 Very High Very High Very High
Necrosis 3 99.34 Very High Very High Very High
INFLAMMATION 17 99.28 Very High Very High Very High
Cancer 3 99.16 Very High Very High Very High
Inflammatory Bowel Disease 1 88.16 High High
Pain 3 83.64 Quite High
Colitis 2 78.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DSS and CARR produced a marked diffuse inflammatory response in the colon and a subsequent 5-fold increase of all eicosanoids after DSS, whereas after CARR only a 2-fold increase of PGs was observed.
Gene_expression (produced) of CARR in colon associated with inflammatory response
1) Confidence 0.51 Published 1992 Journal Agents Actions Section Abstract Doc Link 1442339 Disease Relevance 0.43 Pain Relevance 0.18
ST1 (1, 5, and 10 mg/kg) decreased the nitric oxide (NO) levels on both the edema paw and serum level at 5 h after Carr injection.
Gene_expression (injection) of Carr in paw associated with pressure and volume under development
2) Confidence 0.31 Published 2010 Journal J. Agric. Food Chem. Section Abstract Doc Link 20507140 Disease Relevance 0.98 Pain Relevance 0.40
We also demonstrated that ST1 significantly attenuated the malondialdehyde (MDA) level in the edema paw at 5 h after Carr injection.
Gene_expression (injection) of Carr in paw associated with pressure and volume under development
3) Confidence 0.31 Published 2010 Journal J. Agric. Food Chem. Section Abstract Doc Link 20507140 Disease Relevance 0.95 Pain Relevance 0.40
Also, ST1 (5 and 10 mg/kg) diminished the serum tumor necrosis factor (TNF-alpha) at 5 h after Carr injection.
Gene_expression (injection) of Carr associated with necrosis and cancer
4) Confidence 0.31 Published 2010 Journal J. Agric. Food Chem. Section Abstract Doc Link 20507140 Disease Relevance 0.99 Pain Relevance 0.39

General Comments

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