INT98901

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Context Info
Confidence 0.07
First Reported 2001
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.08
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Acta2) cytoplasm (Acta2)
Anatomy Link Frequency
smooth muscle 2
hepatocytes 1
Acta2 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 10 97.36 Very High Very High Very High
anesthesia 7 90.56 High High
Paracetamol 2 65.80 Quite High
dexamethasone 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 8 97.36 Very High Very High Very High
Cancer 3 91.56 High High
Hamartoma 3 91.28 High High
Hepatocellular Cancer 8 90.20 High High
Calcification 3 84.52 Quite High
Bone Cancer 4 82.72 Quite High
Graft Vs Host Disease 4 80.48 Quite High
Chromosomal Instability 2 79.12 Quite High
Liver Disease 4 73.12 Quite High
Injury 8 62.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemical staining showed positivity for alpha-smooth muscle actin (SMA), but was negative for S-100 protein, myoglobin, keratin, and vimentin.
alpha-smooth muscle actin Binding (positivity) of in smooth muscle
1) Confidence 0.07 Published 2001 Journal Breast Cancer Section Abstract Doc Link 11668248 Disease Relevance 0.34 Pain Relevance 0.09
Independently of age, MSC transplanted into liver did not differentiate into hepatocytes but remained mesenchymal and expressed collagen and alpha smooth muscle actin (?
alpha smooth muscle actin Binding (collagen) of in hepatocytes
2) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.64 Pain Relevance 0.12
Engrafted MSC in liver express alpha smooth muscle actin and their localization merges with collagen deposition
alpha smooth muscle actin Binding (merges) of in smooth muscle
3) Confidence 0.02 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.10 Pain Relevance 0.05

General Comments

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