INT98920

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.52
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.77
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (CREB1) signal transduction (CREB1) mitochondrion (CREB1)
nucleolus (CREB1) nucleus (CREB1) transcription factor binding (CREB1)
Anatomy Link Frequency
muscle 1
synovial cells 1
CREB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
qutenza 1 98.80 Very High Very High Very High
rheumatoid arthritis 2 50.00 Quite Low
Enkephalin 2 50.00 Quite Low
Pain 4 5.00 Very Low Very Low Very Low
hyperexcitability 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
backache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fatigue 9 100.00 Very High Very High Very High
Cancer 40 98.78 Very High Very High Very High
Cystitis 9 96.44 Very High Very High Very High
Bone Cancer 8 84.84 Quite High
Clear Cell Sarcoma 28 73.28 Quite High
Rheumatoid Arthritis 3 56.64 Quite High
Sarcoma 6 5.00 Very Low Very Low Very Low
Chondrosarcoma 5 5.00 Very Low Very Low Very Low
Liposarcoma 5 5.00 Very Low Very Low Very Low
Back Injuries 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Small blue round cell tumor of the interosseous membrane bearing a t(2;22)(q34;q12)/EWS-CREB1 translocation: a case report

Background

Localization (translocation) of CREB1 associated with cancer
1) Confidence 0.52 Published 2010 Journal Mol Cytogenet Section Title Doc Link PMC2908072 Disease Relevance 0.61 Pain Relevance 0
The opioid peptides inhibited nuclear translocation and phosphorylation of the transcription factor, cyclic AMP responsive element binding protein (CREB) in RA synovial cells.
Localization (translocation) of cyclic AMP responsive element binding protein in synovial cells
2) Confidence 0.18 Published 2001 Journal J. Rheumatol. Section Body Doc Link 11669152 Disease Relevance 0.11 Pain Relevance 0
We are uncertain why passive fatigue of spinal tissue did not result in changes in the timing of reflexive or anticipatory trunk muscle onsets yet active fatigue of the trunk muscles appears to result in an earlier onset when muscle firing occurs.
Localization (fatigue) of active in muscle associated with fatigue
3) Confidence 0.07 Published 2005 Journal Chiropr Osteopat Section Body Doc Link PMC1315330 Disease Relevance 0.44 Pain Relevance 0
Colocalization of p-CREB and Trk receptor(s) showed that a subpopulation of p-CREB-IR cells expressed p-Trk with cystitis.
Localization (Colocalization) of CREB associated with cystitis
4) Confidence 0.07 Published 2004 Journal J. Comp. Neurol. Section Abstract Doc Link 14694538 Disease Relevance 0.60 Pain Relevance 0.10

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox