INT98967

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Context Info
Confidence 0.60
First Reported 2001
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.15
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (SP1) nucleus (SP1) intracellular (SP1)
DNA binding (SP1) transcription factor binding (SP1) cytoplasm (SP1)
Anatomy Link Frequency
vesicle 1
SP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 77.76 Quite High
mu opioid receptor 6 74.92 Quite High
Enkephalin 1 74.16 Quite High
agonist 1 71.28 Quite High
Analgesic 1 68.72 Quite High
Morphine 2 68.24 Quite High
antagonist 1 64.88 Quite High
narcan 1 63.92 Quite High
TRP channel 2 5.00 Very Low Very Low Very Low
member 8 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 10 77.16 Quite High
Polycystic Kidney Disease 8 50.00 Quite Low
Autosomal Dominant Polycystic Kidney 3 5.00 Very Low Very Low Very Low
Renal Failure 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Cyst 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Methylation interference analysis localized the Sp1 binding site to the sequence CCCTCCTCCC (-310 to -301) and also suggested that additional transcription factors, other than Sp1-related proteins, contacted the -321 to -301 sequence.
Localization (localized) of Sp1
1) Confidence 0.60 Published 2001 Journal Gene Section Abstract Doc Link 11675004 Disease Relevance 0 Pain Relevance 0.66
SpREJ1 localizes to the plasma membrane covering the acrosomal vesicle and to the flagellar membrane [10].
Localization (localizes) of SpREJ1 in vesicle
2) Confidence 0.02 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1934368 Disease Relevance 0.15 Pain Relevance 0

General Comments

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