INT98986

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Context Info
Confidence 0.53
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.11
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (IL18R1) plasma membrane (IL18R1) intracellular (IL18R1)
IL18R1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 10 100.00 Very High Very High Very High
Inflammation 10 98.14 Very High Very High Very High
Osteoarthritis 112 97.56 Very High Very High Very High
Inflammatory marker 1 84.28 Quite High
local anesthetic 1 74.52 Quite High
antagonist 1 61.92 Quite High
Pain 3 44.16 Quite Low
rheumatoid arthritis 4 5.00 Very Low Very Low Very Low
endometriosis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mucositis 1 98.14 Very High Very High Very High
Osteoarthritis 114 97.56 Very High Very High Very High
INFLAMMATION 8 86.16 High High
Necrosis 1 80.88 Quite High
Cancer 1 80.52 Quite High
Hypersensitivity 2 71.60 Quite High
Osteophyte 1 50.92 Quite High
Pain 3 44.16 Quite Low
Disease 10 37.00 Quite Low
Rheumatoid Arthritis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the human genome, IL1R2, IL1R1, IL1RL2, IL1RL1, IL18R1 and IL18RAP are located in a 470 kb cluster on 2q11.
Localization (located) of IL18R1
1) Confidence 0.53 Published 2010 Journal BMC Med Genet Section Body Doc Link PMC2859817 Disease Relevance 0.57 Pain Relevance 0.33
Mucosal inflammation symptoms correlated with increased levels of albumin, but not with increased levels of ECP, secreted proinflammatory cytokines or cytokine gene mRNA expression.
Localization (secreted) of cytokine gene mRNA associated with mucositis, inflammation and cytokine
2) Confidence 0.05 Published 2001 Journal Acta Otolaryngol. Section Abstract Doc Link 11678174 Disease Relevance 0.54 Pain Relevance 0.46

General Comments

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