INT99015

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Context Info
Confidence 0.27
First Reported 2001
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.76
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Selp, Vcam1) cell adhesion (Selp, Vcam1) plasma membrane (Vcam1)
nucleus (Selp) cytoplasm (Selp)
Anatomy Link Frequency
endothelial cells 1
Selp (Mus musculus)
Vcam1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 1 98.50 Very High Very High Very High
Angina 1 93.08 High High
imagery 46 81.60 Quite High
Inflammation 3 76.48 Quite High
Potency 1 46.40 Quite Low
anesthesia 1 5.00 Very Low Very Low Very Low
Thoracotomy 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 12 95.44 Very High Very High Very High
Disease 2 94.60 High High
Atherosclerosis 7 94.28 High High
Cv General 3 Under Development 1 93.08 High High
Stress 1 86.20 High High
Injury 13 78.52 Quite High
Encephalitis 2 76.96 Quite High
INFLAMMATION 1 69.36 Quite High
Vasculitis 1 59.76 Quite High
Rupture 1 19.88 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reconstituted in vitro systems using monocytes on cytokine-activated endothelial cells under shear flow suggested the involvement of P-selectin, L-selectin, VCAM-1, its ligand, VLA-4 integrin and CD18 integrins.
P-selectin Binding (ligand) of VCAM-1 in endothelial cells associated with cytokine
1) Confidence 0.27 Published 2001 Journal Acta Physiol. Scand. Section Abstract Doc Link 11678724 Disease Relevance 1.35 Pain Relevance 0.18
Indeed, single ligand binding to either VCAM-1 or to P-selectin resulted in modest retention of MPIO, which was markedly increased by the combination of ligands against both VCAM-1 and P-selectin [20].
P-selectin Binding (binding) of VCAM
2) Confidence 0.09 Published 2009 Journal Journal of Vascular Research Section Body Doc Link PMC2914450 Disease Relevance 0.41 Pain Relevance 0.17

General Comments

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