INT99034

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Context Info
Confidence 0.41
First Reported 2001
Last Reported 2004
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.92
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (CYP11A1) small molecule metabolic process (CYP11A1)
Anatomy Link Frequency
cleavage 1
CYP11A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 3 66.80 Quite High
analgesia 1 61.92 Quite High
cva 5 48.24 Quite Low
medulla 3 32.72 Quite Low
Enkephalin 1 25.00 Low Low
Neuropeptide 1 25.00 Low Low
cytokine 11 23.76 Low Low
Inflammation 17 5.00 Very Low Very Low Very Low
opiate 3 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 87.76 High High
Cytomegalovirus Infection 1 84.84 Quite High
Nutritional Deficiencies 1 75.00 Quite High
Addisons Disease 2 73.88 Quite High
Critical Illness 3 73.20 Quite High
Fungal Infection 1 71.72 Quite High
Communicable Diseases 1 70.16 Quite High
Sleep Disorders 3 62.96 Quite High
Sepsis 33 61.08 Quite High
Cv General 2 Under Development 5 58.76 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Northern blot analysis demonstrated that levels of adrenal P450scc mRNA and P450(C17) mRNA were not different between the groups.
Negative_regulation (levels) of P450scc
1) Confidence 0.41 Published 2001 Journal J. Neuroendocrinol. Section Abstract Doc Link 11679054 Disease Relevance 0.07 Pain Relevance 0
These drugs may block enzymatic steps such as inhibition of the adrenal P450 cholesterol side-chain cleavage enzyme by aminogluthethimide [29], or partial or full inhibition of the adrenal 11?
Spec (partial) Negative_regulation (inhibition) of cholesterol side-chain cleavage in cleavage
2) Confidence 0.04 Published 2004 Journal Crit Care Section Body Doc Link PMC522845 Disease Relevance 0.84 Pain Relevance 0.10

General Comments

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