INT99173

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Context Info
Confidence 0.25
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Pomc, Pomc, Tyr) cell-cell signaling (Pomc, Pomc) extracellular space (Pomc, Pomc)
generation of precursor metabolites and energy (Pomc, Pomc) signal transduction (Pomc, Pomc) extracellular region (Pomc, Pomc)
Pomc (Mus musculus)
Pomc (Mus musculus)
Tyr (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 6 94.52 High High
antagonist 3 76.72 Quite High
melanocortin 1 receptor 1 75.00 Quite High
Potency 1 32.64 Quite Low
Disease Link Frequency Relevance Heat
Skin Cancer 1 84.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alpha-MSH-induced tyrosinase activation and melanin production were completely inhibited by a 100-fold higher concentration of AP9 l -131; the IC50 values for AP91-131 in thetwo assay systems were 91 +/- 22 nM and 95 +/- 15 nM respectively.
Alpha-MSH Positive_regulation (induced) of Alpha-MSH Positive_regulation (activation) of tyrosinase
1) Confidence 0.25 Published 2001 Journal J. Recept. Signal Transduct. Res. Section Abstract Doc Link 11693171 Disease Relevance 0.08 Pain Relevance 0.35

General Comments

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