INT99357

Context Info Confidence 0.67 First Reported 2001 Last Reported 2001 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.51 Pain Relevance 1.52

endosome (PMEL) extracellular region (PMEL) Golgi apparatus (PMEL) endoplasmic reticulum (PMEL) plasma membrane (PMEL)

Anatomy Link Frequency blood 4 PMEL (Homo sapiens)

Pain Link Frequency Relevance Heat anesthesia 16 99.84 Opioid 2 93.40 Inflammation 4 81.28 cytokine 2 80.24

Disease Link Frequency Relevance Heat Stupor 2 99.00 Stress 2 81.44 INFLAMMATION 4 81.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We found a significant enhancement of interferon-gamma (IFN-gamma) and soluble interleukin-2 receptor (sIL-2R) release in lipopolysaccharide (LPS)-stimulated whole blood cultures after induction of anesthesia.

Positive_regulation (enhancement) of Localization (release) of sIL in blood associated with anesthesia

1) Confidence 0.67 Published 2001 Journal J. Interferon Cytokine Res. Section Abstract Doc Link 11710990 Disease Relevance 0.26 Pain Relevance 0.76

We found a significant enhancement of interferon-gamma (IFN-gamma) and soluble interleukin-2 receptor (sIL-2R) release in lipopolysaccharide (LPS)-stimulated whole blood cultures after induction of anesthesia.

Positive_regulation (induction) of Localization (release) of sIL in blood associated with anesthesia

2) Confidence 0.49 Published 2001 Journal J. Interferon Cytokine Res. Section Abstract Doc Link 11710990 Disease Relevance 0.26 Pain Relevance 0.76

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