INT99530

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Context Info
Confidence 0.05
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (PCK1) lyase activity (PCK1) carbohydrate metabolic process (PCK1)
lipid metabolic process (PCK1) cytoplasm (PCK1) cytosol (PCK1)
Anatomy Link Frequency
liver 2
PCK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tramadol 11 99.98 Very High Very High Very High
Opioid 3 93.20 High High
narcan 4 87.84 High High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 8 98.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, similar repeated treatments with tramadol reversed the elevated mRNA and protein levels of phosphoenolpyruvate carboxykinase in the liver of STZ-induced diabetic rats.
Negative_regulation (reversed) of Gene_expression (levels) of carboxykinase in liver associated with tramadol and diabetes mellitus
1) Confidence 0.05 Published 2001 Journal Diabetes Section Abstract Doc Link 11723065 Disease Relevance 0.54 Pain Relevance 1.17

General Comments

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