INT99710

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Context Info
Confidence 0.27
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.32
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Met) plasma membrane (Met) cytoplasm (Met)
Anatomy Link Frequency
HGF 2
keratinocyte 2
Met (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Pancreatic Cancer 3 100.00 Very High Very High Very High
Pancreatitis 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These peptide growth factors and their receptors c-met and keratinocyte growth factor receptor (KGFR) are overexpressed in pancreatic cancer.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of c-met in keratinocyte associated with pancreatic cancer
1) Confidence 0.27 Published 2001 Journal Eur. J. Clin. Invest. Section Abstract Doc Link 11737224 Disease Relevance 0.17 Pain Relevance 0.07
CONCLUSIONS: The significant increase of HGF and c-met expression suggests an essential role of this growth factor in the morphological changes during the development of chronic pancreatitis.
Positive_regulation (increase) of Gene_expression (expression) of c-met in HGF
2) Confidence 0.27 Published 2001 Journal Eur. J. Clin. Invest. Section Body Doc Link 11737224 Disease Relevance 0.06 Pain Relevance 0
Expression of c-met mRNA constantly increased (15-fold).
Positive_regulation (increased) of Gene_expression (Expression) of c-met mRNA
3) Confidence 0.25 Published 2001 Journal Eur. J. Clin. Invest. Section Body Doc Link 11737224 Disease Relevance 0.08 Pain Relevance 0

General Comments

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