INT99713

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Context Info
Confidence 0.45
First Reported 2001
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.92
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Fgf7) extracellular region (Fgf7) Golgi apparatus (Fgf7)
Anatomy Link Frequency
fibroblasts 4
keratinocyte 2
Fgf7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 75.00 Quite High
Immobilon 2 5.00 Very Low Very Low Very Low
Snapping jaw 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 2 100.00 Very High Very High Very High
Wound Healing 32 99.88 Very High Very High Very High
Injury 12 77.92 Quite High
Pancreatitis 2 75.00 Quite High
Temporomandibular Joint Syndrome 2 5.00 Very Low Very Low Very Low
Immunization 2 5.00 Very Low Very Low Very Low
Overdose 2 5.00 Very Low Very Low Very Low
Osteoporosis 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Focal Cartilage Defect 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
During the process of wound healing, the expression of KGF was increased not only in chondrocytes but also in fibroblasts.
Positive_regulation (increased) of Gene_expression (expression) of KGF in fibroblasts associated with wound healing
1) Confidence 0.45 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2896696 Disease Relevance 0.37 Pain Relevance 0
These results may indicate that the higher expression of KGF can induce the regeneration of cartilage through the proliferation of fibroblasts.
Positive_regulation (induce) of Gene_expression (expression) of KGF in fibroblasts
2) Confidence 0.45 Published 2010 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2896696 Disease Relevance 0.31 Pain Relevance 0
These peptide growth factors and their receptors c-met and keratinocyte growth factor receptor (KGFR) are overexpressed in pancreatic cancer.
Positive_regulation (overexpressed) of Gene_expression (overexpressed) of keratinocyte growth factor in keratinocyte associated with pancreatic cancer
3) Confidence 0.43 Published 2001 Journal Eur. J. Clin. Invest. Section Abstract Doc Link 11737224 Disease Relevance 0.17 Pain Relevance 0.07
KGF and KGFR mRNA expression were increased after 14-28 days (5-fold) and then returned to control levels. mRNA expression patterns correlated with changes in the protein expression, whereas protein levels of KGF remained unchanged.
Positive_regulation (increased) of Gene_expression (expression) of KGF
4) Confidence 0.43 Published 2001 Journal Eur. J. Clin. Invest. Section Body Doc Link 11737224 Disease Relevance 0.08 Pain Relevance 0

General Comments

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