INT99724

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Context Info
Confidence 0.36
First Reported 2001
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 4
Disease Relevance 0.14
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ren1) extracellular space (Ren1) extracellular region (Ren1)
intracellular (Ren1) response to stress (Ren1)
Anatomy Link Frequency
plasma 2
Blood 1
Ren1 (Mus musculus)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 3 88.72 High High
cINOD 6 68.52 Quite High
cOX1 4 25.00 Low Low
COX2 3 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 68.28 Quite High
Natriuresis 1 50.00 Quite Low
Hypertension 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Age- and gender-matched wild-type (+/+) and homozygous null mice (-/-) were administered captopril for 7 days, and plasma and renal renin levels and renal renin mRNA expression were measured.
Transcription (expression) of renal renin in plasma
1) Confidence 0.36 Published 2002 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 12184998 Disease Relevance 0.07 Pain Relevance 0.07
ACEI also increased renin mRNA expression (+/+ 2.4 +/- 0.2; -/- 2.1 +/- 0.2 fold control; n = 6-10; P < 0.05).
Transcription (expression) of renin
2) Confidence 0.36 Published 2002 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 12184998 Disease Relevance 0 Pain Relevance 0.04
Age- and gender-matched wild-type (+/+) and homozygous null mice (-/-) were administered captopril for 7 days, and plasma and renal renin levels and renal renin mRNA expression were measured.
Transcription (expression) of renal renin in plasma
3) Confidence 0.31 Published 2002 Journal Am. J. Physiol. Regul. Integr. Comp. Physiol. Section Abstract Doc Link 12184998 Disease Relevance 0.07 Pain Relevance 0.07
Blood pressure, renin mRNA expression, and aldosterone were measured while dietary sodium was varied.
Transcription (expression) of renin in Blood
4) Confidence 0.11 Published 2001 Journal Kidney Int. Section Body Doc Link 11737606 Disease Relevance 0 Pain Relevance 0

General Comments

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