INT99781

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Context Info
Confidence 0.50
First Reported 2001
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.97
Pain Relevance 0.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Cxcl10) extracellular space (Cxcl10) extracellular region (Cxcl10)
Cxcl10 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 14 99.52 Very High Very High Very High
chemokine 13 99.04 Very High Very High Very High
Inflammation 24 97.80 Very High Very High Very High
Paracetamol 5 93.88 High High
interstitial cystitis 41 88.64 High High
cva 1 10.08 Low Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 24 97.80 Very High Very High Very High
Cystitis 70 95.64 Very High Very High Very High
Interstitial Cystitis 41 88.64 High High
Disease 16 84.16 Quite High
Injury 4 75.00 Quite High
Hemorrhage 1 10.08 Low Low
Rupture 1 8.84 Low Low
Hyperplasia 3 5.00 Very Low Very Low Very Low
Inflammatory Bowel Disease 3 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neutralization of CXCR2 during IP-10 therapy resulted in an abrogation of the hepatoprotective effect of IP-10.
Positive_regulation (resulted) of Negative_regulation (abrogation) of IP-10
1) Confidence 0.50 Published 2001 Journal J. Immunol. Section Abstract Doc Link 11739529 Disease Relevance 0.22 Pain Relevance 0.44
The ability of CXCL10 blockade to modulate local chemokines as well as Th1 cytokine mRNA expression and to facilitate the decline of serum levels of CXCL9 and CXCL10 is an indication of reduced local as well as systemic inflammation.
Positive_regulation (facilitate) of Negative_regulation (decline) of CXCL10 associated with chemokine, inflammation and cytokine
2) Confidence 0.44 Published 2008 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC2583981 Disease Relevance 0.75 Pain Relevance 0.37

General Comments

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