INT99845

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Context Info
Confidence 0.73
First Reported 2002
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (P2ry4) plasma membrane (P2ry4) signal transducer activity (P2ry4)
P2ry4 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 3 96.88 Very High Very High Very High
antagonist 1 91.96 High High
adenocard 5 81.76 Quite High
Potency 1 78.20 Quite High
anesthesia 1 25.00 Low Low

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that ATP and UTP cause a decrease in systemic arterial pressure in the mouse via a cAMP-dependent pathway via a novel P2 receptor linked to adenylate cyclase and that nitric oxide release, prostaglandin synthesis, cGMP, and P2X1, P2Y1, and P2Y4 receptors play little or no role in the vascular effects of these purinergic agonists in the mouse.
Localization (release) of P2Y4 associated with agonist
1) Confidence 0.73 Published 2002 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 11743236 Disease Relevance 0 Pain Relevance 0.39

General Comments

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