INT99910

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Context Info
Confidence 0.25
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCB1) mitochondrion (MTX1) ATPase activity (ABCB1)
plasma membrane (ABCB1) transmembrane transport (ABCB1)
MTX1 (Homo sapiens)
ABCB1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Sumatriptan 1 95.84 Very High Very High Very High
methotrexate 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Adenocarcinoma 1 86.88 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The results suggest that the HT29-MTX model can be used to rank order the passive permeability of compounds, irrespective of their potential interaction with P-gp, which may facilitate optimization of the physicochemical features of compounds within a chemical series.
HT29-MTX Binding (interaction) of P-gp
1) Confidence 0.25 Published 2001 Journal J Pharm Sci Section Abstract Doc Link 11745719 Disease Relevance 0.09 Pain Relevance 0.10

General Comments

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