INT99970

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Context Info
Confidence 0.27
First Reported 2001
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 2.35
Pain Relevance 1.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (NGF) signal transduction (NGF) extracellular space (NGF)
extracellular region (NGF)
NGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Nerve growth factor 14 100.00 Very High Very High Very High
Hsan 17 93.28 High High
Pain 2 63.36 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 1 96.84 Very High Very High Very High
Hereditary Sensory And Autonomic Neuropathies 19 93.28 High High
Nociception 2 89.64 High High
Ganglion Cysts 1 88.68 High High
Intellectual Impairment 2 75.16 Quite High
Diabetic Nephropathy 3 75.00 Quite High
Hypohidrosis 3 70.72 Quite High
Fever 2 70.24 Quite High
Pain 1 63.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TRKA mutations are distributed in an extracellular domain involved in NGF binding, as well as in the intracellular signal-transduction domain.
Regulation (involved) of NGF Binding (binding) of associated with nerve growth factor
1) Confidence 0.27 Published 2002 Journal Clin. Auton. Res. Section Abstract Doc Link 12102460 Disease Relevance 1.22 Pain Relevance 1.12
Thirty-seven different TRKA mutations, identified in patients in various countries, including nine frameshift, seven nonsense, seven splice, and 14 missense mutations, are distributed in an extracellular domain involved in NGF binding, as well as in the intracellular signal-transduction domain.
Regulation (involved) of NGF Binding (binding) of associated with nerve growth factor
2) Confidence 0.26 Published 2001 Journal Hum. Mutat. Section Abstract Doc Link 11748840 Disease Relevance 1.13 Pain Relevance 0.81

General Comments

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