J:Acta Anaesthesiol Scand

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT68272 Binding of Oprd1 and G2e3 1 1 0.00 0.11 1.93
2 INT68273 G2e3 Negative_regulation of Binding of Oprd1 and G2e3 1 1 0.00 0.11 1.93
3 INT81127 Binding of Gabrd and Abat 3 1 0.25 0 0.96
4 INT57396 Binding of H2 and Bw1 1 1 0.00 0 0.88
5 INT57395 Binding of H1 and Bw1 1 1 0.00 0 0.88
6 INT109169 Abat Positive_regulation of Phosphorylation of Kcnab3 1 1 0.01 0 0
7 INT109170 Abat Positive_regulation of Nr5a2 1 1 0.03 0 0
8 INT109171 Abat Positive_regulation of Phosphorylation of Nr5a2 1 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT1912 Gene_expression of Calca 1 1152 0.78 453.25 739.84
3 INT155 Positive_regulation of Prl 1 1233 0.70 317.93 457.82
4 INT443 Localization of POMC 4 1020 0.81 284.52 443.17
5 INT50058 Negative_regulation of Cpox 2 907 0.58 426.28 428.29
6 INT9238 Gene_expression of IL6 1 1575 0.78 1135.66 424.22
7 INT467 Gene_expression of POMC 5 1048 0.78 332.8 394.16
8 INT6580 Negative_regulation of Ptgs1 1 929 0.59 381.53 376.26
9 INT720 Positive_regulation of POMC 4 807 0.70 237.37 353.83
10 INT5660 Binding of Oprd1 2 477 0.48 71.86 342.06
11 INT2649 Regulation of Calca 3 433 0.62 146.05 330.95
12 INT5059 Positive_regulation of TNF 2 1050 0.70 896.51 322.81
13 INT162 Regulation of Prl 1 794 0.62 165.01 322.24
14 INT34869 Negative_regulation of PTGS2 1 778 0.59 366.76 319.85
15 INT477 Localization of Avp 1 813 0.81 131.58 300.4
16 INT1352 Localization of Acot1 16 728 0.80 73.01 296.01
17 INT5379 Gene_expression of Fos 4 656 0.78 255.5 292.54
18 INT9158 Gene_expression of Tnf 3 722 0.78 522.01 277.68
19 INT5972 Gene_expression of IL1B 3 948 0.78 510.91 263.97
20 INT16868 Gene_expression of Il6 2 807 0.78 499.48 256.57
21 INT738 Regulation of POMC 5 459 0.62 111.19 243.74
22 INT11313 Positive_regulation of Il6 4 526 0.70 331.27 201.59
23 INT528 Gene_expression of Prl 1 693 0.78 217.18 192.2
24 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
25 INT13353 Positive_regulation of Tnf 2 332 0.70 248.75 148.1
26 INT2451 Positive_regulation of Avp 4 355 0.70 102.66 147.69
27 INT425 Localization of PRL 1 455 0.81 189.64 144.8
28 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
29 INT5061 Negative_regulation of Mme 2 306 0.59 51.97 136.9
30 INT5380 Positive_regulation of Gene_expression of Fos 2 243 0.70 105.65 131.05
31 INT65054 Positive_regulation of Nfkb1 3 285 0.70 149.33 126.73
32 INT6128 Positive_regulation of Localization of POMC 1 256 0.70 68.77 121.64
33 INT12339 Localization of IL8 1 437 0.81 251.87 117.39
34 INT4207 Regulation of Avp 1 267 0.62 63.72 115.33
35 INT12082 Localization of IL6 1 365 0.81 241.78 105.78
36 INT915 Positive_regulation of PRL 1 342 0.70 141.96 104.31
37 INT69440 Gene_expression of ROS1 7 752 0.78 477.64 103.83
38 INT18009 Positive_regulation of CRP 1 518 0.70 553.03 103.74
39 INT11381 Positive_regulation of IL1B 3 330 0.70 209.31 100.9
40 INT203 Positive_regulation of Pomc 1 257 0.70 90.56 92.84
41 INT48767 Negative_regulation of NOS1 1 312 0.59 154.25 90.32
42 INT48408 Gene_expression of ICAM1 1 494 0.78 340.08 88.6
43 INT1635 Gene_expression of Vip 1 245 0.78 53.36 88.13
44 INT1498 Gene_expression of Gh 1 521 0.75 220.84 81.16
45 INT148 Positive_regulation of Gnrhr 3 182 0.70 47.44 79.64
46 INT920 Localization of PLOD1 1 223 0.81 42.25 78.7
47 INT4358 Positive_regulation of Localization of Avp 1 195 0.70 30.79 77.58
48 INT1353 Negative_regulation of Localization of Acot1 4 153 0.53 15.05 75.17
49 INT10274 Positive_regulation of Il1b 1 123 0.70 79.76 73.56
50 INT11380 Negative_regulation of IL1B 3 215 0.59 125.62 72.35
51 INT14049 Positive_regulation of GRIN1 1 102 0.70 48.31 71.06
52 INT58400 Negative_regulation of Tnf 1 182 0.59 129.97 71
53 INT49995 Positive_regulation of Gene_expression of Tnf 4 187 0.70 125.07 70.54
54 INT6849 Localization of IL1B 3 229 0.81 112.56 69.63
55 INT19511 Localization of Il6 1 212 0.81 118.17 67.67
56 INT253 Regulation of PRL 1 184 0.62 47.27 65.79
57 INT3375 Gene_expression of IGHE 5 535 0.77 387.47 65.46
58 INT15613 Negative_regulation of Ptgs2 2 160 0.59 71.08 65.08
59 INT2212 Binding of Abat 1 89 0.48 18.36 63.99
60 INT46 Localization of Ren 3 233 0.81 46.15 62.44
61 INT1169 Negative_regulation of Bche 2 322 0.59 149.22 61.27
62 INT17564 Gene_expression of Gpt 1 322 0.75 208.51 60.36
63 INT3920 Localization of Ldha 4 241 0.81 83.08 58.72
64 INT5453 Regulation of Localization of POMC 1 114 0.62 20.56 56.34
65 INT647 Gene_expression of SGCG 2 211 0.75 78.46 55.82
66 INT19 Regulation of Gnrhr 1 131 0.62 36.4 55.66
67 INT8528 Negative_regulation of Gene_expression of Fos 1 100 0.59 41.15 55.6
68 INT314 Positive_regulation of Ren 3 212 0.70 66.68 55.56
69 INT52800 Negative_regulation of Gene_expression of Tnf 2 142 0.59 92.27 55.47
70 INT251 Regulation of INS 1 398 0.62 232.47 55.04
71 INT49993 Positive_regulation of Gene_expression of Il6 2 149 0.70 88.07 53.78
72 INT9210 Regulation of IL6 1 166 0.62 125.61 49.95
73 INT375 Positive_regulation of REN 1 293 0.70 152.46 47.55
74 INT374 Positive_regulation of Ldha 3 212 0.70 107.08 47.43
75 INT50957 Negative_regulation of Il6 2 134 0.59 79.08 42.67
76 INT9233 Negative_regulation of Gene_expression of IL1B 1 114 0.59 56.99 41.82
77 INT64440 Gene_expression of Pnoc 4 66 0.78 13.61 41.76
78 INT69437 Positive_regulation of ROS1 1 328 0.58 222.83 40.56
79 INT3987 Positive_regulation of IGHE 4 316 0.70 283.2 40.16
80 INT47939 Gene_expression of Selp 2 171 0.76 87.54 39.03
81 INT1931 Positive_regulation of Gene_expression of POMC 3 116 0.70 37.26 38.67
82 INT3188 Regulation of Localization of Acot1 1 84 0.59 8.94 38.56
83 INT65889 Gene_expression of RETNLB 1 73 0.34 60.98 38.3
84 INT385 Gene_expression of Agt 6 182 0.78 63.62 37.91
85 INT3971 Positive_regulation of Alb 2 175 0.70 98.46 36.45
86 INT390 Positive_regulation of Agt 3 170 0.70 61.47 36.08
87 INT49 Negative_regulation of Ren 2 129 0.59 37.48 35.62
88 INT316 Regulation of Cebpz 1 105 0.00 27.21 35.41
89 INT3679 Gene_expression of AVP 1 171 0.78 72.9 35.23
90 INT65055 Negative_regulation of Nfkb1 2 83 0.58 44.85 34.94
91 INT326 Gene_expression of Gnrhr 1 105 0.76 35.87 34.93
92 INT18893 Positive_regulation of CPP 2 81 0.69 38.03 34.33
93 INT8905 Gene_expression of EDN1 2 215 0.78 157.1 34.19
94 INT5489 Localization of CA2 4 172 0.80 39.46 33.56
95 INT3913 Positive_regulation of ABAT 1 47 0.69 22.73 33.4
96 INT65536 Negative_regulation of Positive_regulation of Nfkb1 2 77 0.59 38.86 33.33
97 INT1116 Regulation of Ren 1 103 0.62 27.66 33.26
98 INT2330 Regulation of CB 1 78 0.10 20.46 32.6
99 INT81530 Gene_expression of Nfkb1 1 93 0.78 48.58 32.58
100 INT1159 Negative_regulation of Agt 1 133 0.59 40.14 31.67
101 INT610 Regulation of PENK 1 47 0.62 14.17 31.55
102 INT56290 Negative_regulation of Gene_expression of Il6 1 79 0.59 47.98 31.07
103 INT72923 Positive_regulation of MCRS1 2 72 0.50 99.19 30.36
104 INT6196 Regulation of Nppa 2 83 0.62 30.31 30.18
105 INT724 Negative_regulation of Alb 4 151 0.59 93.57 29.65
106 INT67912 Gene_expression of GRIN1 1 75 0.77 28.99 29.28
107 INT2532 Negative_regulation of Cebpz 1 98 0.00 53.06 28.57
108 INT9199 Positive_regulation of CEBPZ 1 111 0.67 30.99 28.45
109 INT22211 Positive_regulation of CYP3A4 2 110 0.70 22 28.27
110 INT52722 Localization of RETNLB 1 54 0.38 48.63 27.98
111 INT5653 Positive_regulation of ELANE 1 136 0.70 72.78 27.94
112 INT14575 Positive_regulation of Ppt1 1 60 0.70 9.97 27.4
113 INT7894 Negative_regulation of Vip 1 59 0.59 11.76 27.36
114 INT21687 Positive_regulation of ras 1 143 0.58 97.34 27.31
115 INT97 Negative_regulation of Adrb1 1 102 0.59 32.44 26.9
116 INT5650 Gene_expression of Mpo 2 117 0.77 80.27 26.42
117 INT65537 Positive_regulation of Positive_regulation of Nfkb1 3 52 0.67 30.6 26.35
118 INT5948 Regulation of Il1b 1 44 0.60 22.8 25.4
119 INT61664 Regulation of GRIN1 2 38 0.60 16.45 25.35
120 INT49141 Gene_expression of Selp 4 157 0.78 85.22 24.78
121 INT3028 Negative_regulation of Oxt 1 76 0.58 18.52 24.4
122 INT10349 Negative_regulation of Il1b 1 48 0.58 25.53 24.24
123 INT10835 Regulation of IL8 1 79 0.49 53.04 24.14
124 INT682 Negative_regulation of AVP 1 97 0.59 50.67 23.91
125 INT11303 Gene_expression of Avp 2 116 0.78 39.23 23.88
126 INT250 Regulation of GHRH 1 65 0.61 17.46 23.19
127 INT74423 Localization of IL10 1 91 0.80 61.6 22.95
128 INT7678 Localization of Alb 1 142 0.81 80.93 22.49
129 INT4369 Gene_expression of Ldha 4 157 0.76 88.12 22.45
130 INT66753 Negative_regulation of Positive_regulation of Tnf 2 45 0.59 35.28 22.33
131 INT8580 Gene_expression of ELANE 3 132 0.75 62.98 21.79
132 INT1644 Regulation of FSHR 1 77 0.55 15.62 21.49
133 INT28001 Gene_expression of Gpm6a 1 23 0.66 16.66 21.09
134 INT52529 Regulation of Nfkb1 1 48 0.61 26.2 20.89
135 INT8662 Positive_regulation of EDN1 4 144 0.70 125.34 19.59
136 INT37835 Negative_regulation of CPP 4 61 0.51 31.34 18.57
137 INT1975 Regulation of Regulation of Prl 1 32 0.59 5.78 18.53
138 INT3060 Negative_regulation of Bche 2 94 0.59 46.75 18.51
139 INT55335 Binding of Cpox 2 49 0.34 15.48 18.46
140 INT7474 Gene_expression of Man2a2 1 38 0.67 3.31 18.42
141 INT15470 Regulation of CPP 2 42 0.48 26.1 18.25
142 INT3118 Negative_regulation of Positive_regulation of POMC 1 33 0.59 9.42 18.07
143 INT18621 Binding of ABAT 1 28 0.36 9.88 18.04
144 INT48 Positive_regulation of Localization of Ren 1 69 0.70 12.47 18.03
145 INT1642 Negative_regulation of Localization of PLOD1 1 40 0.58 10.67 17.95
146 INT10555 Gene_expression of FLII 1 37 0.75 7.81 17.6
147 INT6791 Binding of NA 1 55 0.46 5.36 17.59
148 INT50579 Binding of CYP3A4 1 84 0.48 17.52 17.45
149 INT7580 Positive_regulation of Mbp 1 54 0.70 23.37 17.14
150 INT213 Negative_regulation of Localization of AVP 1 46 0.59 19.78 16.79
151 INT6129 Positive_regulation of Localization of AVP 1 63 0.70 30.44 16.64
152 INT65659 Positive_regulation of STAT3 1 132 0.70 69.56 15.95
153 INT3793 Regulation of CEBPZ 1 59 0.61 20.91 15.83
154 INT4340 Positive_regulation of Localization of Ldha 2 46 0.70 14.52 15.66
155 INT2630 Positive_regulation of Shbg 1 134 0.70 65.26 15.19
156 INT74587 Gene_expression of MMP8 1 31 0.78 24.4 14.91
157 INT170 Negative_regulation of Adrb1 1 52 0.55 13.46 14.78
158 INT5904 Localization of MPO 1 62 0.81 36.37 14.64
159 INT25266 Positive_regulation of Localization of IL1B 1 38 0.69 15.89 14.35
160 INT39507 Positive_regulation of TXNRD1 1 37 0.68 12.47 14.25
161 INT7997 Gene_expression of Ltc4s 1 51 0.76 34.28 13.8
162 INT65697 Positive_regulation of GRIN3B 1 23 0.69 12.52 13.78
163 INT64048 Positive_regulation of Positive_regulation of Tnf 1 32 0.70 21.24 13.74
164 INT69435 Negative_regulation of ROS1 1 74 0.51 50.38 13.71
165 INT17565 Regulation of Gpt 1 85 0.60 43.64 13.68
166 INT19191 Negative_regulation of Localization of IL1B 2 35 0.58 15.19 13.63
167 INT14572 Binding of INS 1 205 0.48 175.43 13.38
168 INT7465 Negative_regulation of Mbp 2 53 0.58 19.12 13.27
169 INT3962 Regulation of AGT 1 50 0.62 20.96 13.01
170 INT55255 Positive_regulation of Localization of Il6 1 48 0.69 24.88 12.76
171 INT60865 Gene_expression of G2e3 1 20 0.73 2.1 12.76
172 INT78797 Regulation of Tmem132a 1 8 0.45 3.61 12.73
173 INT3244 Negative_regulation of eCB 2 37 0.03 16.69 12.61
174 INT90184 Gene_expression of KCNJ6 1 7 0.67 4.14 12.57
175 INT12191 Negative_regulation of Localization of Ldha 2 35 0.59 13.71 12.35
176 INT12084 Regulation of Localization of IL6 1 36 0.61 20.32 12.34
177 INT69436 Negative_regulation of Gene_expression of ROS1 3 81 0.38 46.58 12.22
178 INT9832 Gene_expression of Shbg 1 96 0.75 56.71 12.19
179 INT32203 Negative_regulation of Crp 1 48 0.58 32.77 11.89
180 INT65057 Regulation of Nfkb1 1 28 0.47 16.48 11.62
181 INT58775 Binding of G2e3 1 10 0.33 0.19 11.52
182 INT373 Regulation of Ldha 1 37 0.61 17.86 11.41
183 INT11673 Positive_regulation of ECT 2 43 0.59 13.93 11.25
184 INT12444 Binding of Gabrd 2 26 0.48 4.7 11.23
185 INT81531 Positive_regulation of Gene_expression of Nfkb1 1 27 0.69 13.9 11.04
186 INT3301 Positive_regulation of Slc43a3 2 26 0.55 5.48 10.81
187 INT83886 Negative_regulation of HMOX2 1 27 0.43 11.69 10.78
188 INT701 Localization of IGHE 2 87 0.80 40.5 10.62
189 INT72924 Negative_regulation of MCRS1 1 27 0.19 33.59 10.29
190 INT348 Regulation of Adra1a 1 25 0.45 3.33 10.27
191 INT327 Negative_regulation of Positive_regulation of Gnrhr 1 17 0.53 4.22 10.21
192 INT95632 Positive_regulation of MMP8 1 26 0.70 10.06 9.96
193 INT80110 Regulation of Positive_regulation of TNF 1 34 0.44 25.79 9.78
194 INT35164 Negative_regulation of IGHE 2 96 0.58 76.3 9.74
195 INT4494 Regulation of GCG 2 41 0.45 18.38 9.68
196 INT11788 Positive_regulation of Rrsv 1 36 0.46 10.08 9.68
197 INT3988 Positive_regulation of Gene_expression of IGHE 1 98 0.68 91.46 9.61
198 INT1648 Regulation of LHB 1 21 0.61 3.32 9.6
199 INT12563 Localization of Mpo 2 33 0.81 20.99 9.58
200 INT71174 Gene_expression of CASP1 1 44 0.75 30.3 9.37
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