J:Acta Neuropathol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT205135 Binding of APOE and APP 1 1 0.05 0.35 0.08
2 INT318028 Binding of IRF6 and Tlr4 1 2 0.00 0.61 0.06
3 INT217402 Binding of Bace1 and PSENEN 1 1 0.02 0.72 0
4 INT217399 Binding of Bace1 and Ncstn 1 1 0.05 0.72 0
5 INT217398 Binding of Psen2 and Bace1 1 2 0.12 1.44 0
6 INT217400 Binding of Psen1 and Bace1 1 2 0.17 1.43 0
7 INT217396 Binding of Abca1 and App 1 1 0.26 0.83 0
8 INT217397 Binding of Bace1 and Alph1 1 1 0.02 0.73 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9659 Gene_expression of Il6 2 991 0.78 715.11 265.57
2 INT7506 Negative_regulation of Ltp 3 267 0.46 91.01 176.8
3 INT5842 Gene_expression of Gfap 1 372 0.78 153.71 127.71
4 INT90091 Gene_expression of GOPC 5 967 0.67 366.22 103.6
5 INT65500 Gene_expression of App 62 605 0.78 429.94 98.31
6 INT169926 Positive_regulation of Gopc 1 416 0.46 157.8 58.67
7 INT157666 Positive_regulation of GOPC 1 335 0.60 120.19 42.75
8 INT118343 Positive_regulation of Eae1 1 121 0.39 136.06 34.87
9 INT124860 Gene_expression of Bace1 4 330 0.78 157.11 31.65
10 INT29743 Negative_regulation of App 6 91 0.59 65.56 31.26
11 INT130837 Gene_expression of Aqp4 9 205 0.78 151.23 29.63
12 INT47712 Positive_regulation of App 10 135 0.69 101.38 28.94
13 INT118734 Gene_expression of Tlr4 1 70 0.78 55.7 28.19
14 INT116861 Gene_expression of Apoe 9 182 0.78 100.41 27.26
15 INT111081 Gene_expression of CA1 1 19 0.75 51.09 26.64
16 INT11159 Gene_expression of EGFR 2 698 0.78 548.93 25.69
17 INT89662 Positive_regulation of Gene_expression of App 24 169 0.70 133.36 25.62
18 INT44954 Gene_expression of APP 8 191 0.78 105.86 23.9
19 INT6868 Gene_expression of GFAP 4 136 0.78 84.65 22.7
20 INT102112 Gene_expression of Prnp 23 440 0.78 209.32 22.5
21 INT11625 Localization of App 3 98 0.78 55.46 20.86
22 INT105021 Binding of GOPC 1 187 0.40 60.39 20.38
23 INT16794 Binding of App 6 103 0.48 64.87 19.79
24 INT65502 Regulation of App 1 77 0.62 52.05 19.44
25 INT15148 Gene_expression of Vip 1 51 0.77 25.61 18.33
26 INT26972 Negative_regulation of Tenc1 1 57 0.57 56.71 16.87
27 INT23657 Positive_regulation of APP 3 64 0.70 39.76 16.68
28 INT10214 Gene_expression of VIM 1 153 0.78 115.88 16.29
29 INT899 Gene_expression of F13A1 1 122 0.70 78.02 16.26
30 INT8571 Gene_expression of B3GAT1 1 54 0.75 36.85 15.98
31 INT111073 Gene_expression of Psen1 9 167 0.76 78.65 15.83
32 INT131296 Positive_regulation of Bace1 1 208 0.70 170.1 15.79
33 INT1752 Negative_regulation of Ache 1 109 0.59 42.05 15.73
34 INT68913 Gene_expression of Cd14 1 55 0.76 38.99 15.67
35 INT171666 Regulation of GOPC 1 117 0.39 40.41 15.47
36 INT96775 Gene_expression of Pdgfa 1 42 0.54 29.78 15.46
37 INT109511 Gene_expression of Bax 1 133 0.78 113.22 14.36
38 INT22046 Negative_regulation of IRF6 1 52 0.43 25.69 14.13
39 INT16919 Gene_expression of IL36RN 1 48 0.48 32.78 13.83
40 INT69569 Positive_regulation of Prnp 1 175 0.70 96.31 13.34
41 INT26545 Gene_expression of Hras1 1 173 0.78 79.54 13.21
42 INT24876 Gene_expression of CD34 2 172 0.78 91.02 12.39
43 INT107916 Protein_catabolism of App 2 114 1.00 66.71 12.38
44 INT11793 Negative_regulation of CA2 1 78 0.57 19.63 12.35
45 INT26973 Gene_expression of Tenc1 2 59 0.66 27.19 12
46 INT65501 Regulation of Gene_expression of App 8 56 0.62 32.51 11.48
47 INT98789 Negative_regulation of Gene_expression of App 7 54 0.58 40.27 11.15
48 INT15054 Gene_expression of Mme 3 48 0.77 42.52 10.63
49 INT27651 Gene_expression of S100A12 2 45 0.76 52.25 10.51
50 INT6431 Positive_regulation of Ass1 1 36 0.24 8.08 10.43
51 INT17741 Gene_expression of MBP 1 67 0.78 23.67 9.65
52 INT46273 Gene_expression of PRNP 5 103 0.78 110.34 9.25
53 INT57549 Gene_expression of GNPTAB 2 49 0.65 57.5 9.05
54 INT91772 Gene_expression of PSEN1 4 115 0.75 38.12 8.48
55 INT178198 Gene_expression of C3 1 62 0.78 39.5 7.69
56 INT24891 Gene_expression of SYP 4 55 0.75 45.76 7.53
57 INT202868 Positive_regulation of Car1 1 30 0.44 15.48 7.42
58 INT136304 Negative_regulation of Aqp4 13 54 0.59 48.42 7.4
59 INT6861 Negative_regulation of Gfap 2 32 0.58 13.71 7.22
60 INT55957 Positive_regulation of PRNP 3 57 0.67 37.87 7.11
61 INT197493 Localization of Apoe 1 61 0.79 27.48 7.06
62 INT156489 Positive_regulation of Gene_expression of Bace1 1 67 0.69 41.07 7.02
63 INT142264 Positive_regulation of Apoe 2 47 0.50 26.35 6.94
64 INT63042 Binding of Apoe 4 59 0.48 31.23 5.88
65 INT84572 Gene_expression of Zmat3 3 67 0.07 37.61 5.86
66 INT69572 Localization of Prnp 3 96 0.81 38.11 5.45
67 INT160853 Gene_expression of Syp 3 87 0.72 20.06 5.31
68 INT18681 Gene_expression of Thy1 4 80 0.71 38.8 5.23
69 INT99823 Positive_regulation of Gene_expression of APP 2 31 0.70 21.52 5.09
70 INT16214 Localization of F13A1 1 36 0.74 21.8 4.87
71 INT102254 Positive_regulation of Gene_expression of Prnp 2 72 0.70 38.11 4.81
72 INT87780 Gene_expression of Gja1 1 22 0.77 5.84 4.24
73 INT58003 Localization of APP 4 32 0.80 13.75 4.2
74 INT111067 Positive_regulation of Gene_expression of Psen1 2 32 0.68 21.2 4.19
75 INT159119 Negative_regulation of Car1 1 17 0.37 6.6 4.01
76 INT99821 Negative_regulation of Gene_expression of APP 2 20 0.42 15.21 3.94
77 INT169748 Positive_regulation of Gene_expression of Aqp4 1 38 0.69 34.29 3.79
78 INT98624 Regulation of Aqp4 3 27 0.62 30.76 3.77
79 INT104624 Negative_regulation of Apoe 1 26 0.59 19.25 3.71
80 INT134786 Gene_expression of Adam10 1 17 0.68 7.61 3.29
81 INT217389 Negative_regulation of Gene_expression of Bace1 1 43 0.59 18.57 3.27
82 INT102255 Regulation of Prnp 1 35 0.62 18.97 3.25
83 INT2837 Regulation of PAEP 1 17 0.53 7.84 3.17
84 INT156488 Binding of Bace1 1 46 0.48 15.64 3.04
85 INT154334 Localization of S100A12 1 9 0.80 9.32 2.89
86 INT50080 Binding of APOE 1 38 0.45 29.61 2.67
87 INT89543 Gene_expression of NEFL 1 18 0.75 10.6 2.67
88 INT102253 Negative_regulation of Prnp 2 75 0.59 24.23 2.62
89 INT169987 Transcription of GOPC 1 45 0.60 21.88 2.61
90 INT178291 Gene_expression of Hps1 1 26 0.67 8.2 2.52
91 INT210527 Positive_regulation of Gene_expression of Tenc1 1 14 0.38 6.37 2.45
92 INT111072 Protein_catabolism of Bace1 1 26 0.98 14.07 2.41
93 INT57970 Positive_regulation of Rb1 1 17 0.67 7.03 2.36
94 INT105761 Binding of GFAP 1 13 0.36 14.94 2.32
95 INT225966 Regulation of Gene_expression of Aqp4 1 18 0.62 20.39 2.3
96 INT27590 Negative_regulation of Phex 1 5 0.36 2.38 2.26
97 INT142265 Regulation of Apoe 1 20 0.60 9.52 2.23
98 INT124772 Regulation of Binding of App 2 6 0.45 4.92 2.09
99 INT51980 Protein_catabolism of Mme 1 6 0.89 2.49 2.06
100 INT60723 Localization of Psen2 1 5 0.68 2.11 2.02
101 INT222609 Binding of Tlr4 1 8 0.43 4.03 1.98
102 INT190883 Gene_expression of Apoc3 2 16 0.38 14.18 1.93
103 INT193939 Binding of PSEN1 1 10 0.36 6.16 1.93
104 INT198885 Gene_expression of Lrp1 3 33 0.57 10.2 1.91
105 INT111070 Negative_regulation of Gene_expression of Psen1 4 17 0.42 9.47 1.77
106 INT217382 Regulation of Gene_expression of Bace1 1 26 0.61 17 1.76
107 INT194242 Positive_regulation of Gene_expression of MBP 1 9 0.45 4.1 1.71
108 INT203508 Gene_expression of Eno2 2 12 0.65 4.98 1.55
109 INT164480 Negative_regulation of Gene_expression of Aqp4 1 14 0.58 10.84 1.52
110 INT133863 Positive_regulation of Protein_catabolism of App 1 12 0.59 7.53 1.52
111 INT58004 Positive_regulation of Localization of APP 2 5 0.46 2.1 1.5
112 INT51486 Negative_regulation of GNPTAB 1 11 0.41 8.18 1.45
113 INT53929 Positive_regulation of GNPTAB 1 12 0.32 6.66 1.4
114 INT217388 Negative_regulation of Gene_expression of Apoe 2 11 0.59 6.07 1.4
115 INT73673 Negative_regulation of Mtap2 3 9 0.32 8.25 1.4
116 INT104731 Positive_regulation of NEFL 1 13 0.67 9.22 1.37
117 INT141131 Positive_regulation of Gene_expression of PRNP 1 12 0.61 16.6 1.36
118 INT181509 Negative_regulation of Psen1 1 17 0.57 11.53 1.35
119 INT45075 Gene_expression of Sugt1 1 24 0.27 8.5 1.33
120 INT170900 Regulation of Positive_regulation of Gopc 1 10 0.20 3.44 1.24
121 INT61993 Gene_expression of NF1 2 29 0.78 34.47 1.23
122 INT154333 Positive_regulation of Localization of S100A12 1 4 0.69 3.9 1.19
123 INT217390 Negative_regulation of Positive_regulation of Apoe 1 3 0.37 1.95 1.05
124 INT204737 Negative_regulation of Gene_expression of Prnp 2 32 0.59 18.96 1.03
125 INT179535 Negative_regulation of C1qa 1 10 0.57 4.7 1.03
126 INT73450 Gene_expression of Pilra 1 7 0.05 2.87 0.97
127 INT185969 Regulation of Syp 2 5 0.57 2.58 0.92
128 INT198872 Binding of Lrp1 1 9 0.36 2.73 0.89
129 INT185973 Negative_regulation of Syp 4 16 0.54 2.83 0.87
130 INT167607 Positive_regulation of Binding of App 1 8 0.50 2.97 0.86
131 INT82374 Binding of SYP 1 13 0.36 13.69 0.85
132 INT197494 Gene_expression of Apoa4 5 9 0.05 7.33 0.78
133 INT68297 Binding of MAPT 1 9 0.47 4.45 0.75
134 INT100601 Localization of PRNP 4 17 0.66 13.61 0.71
135 INT28204 Positive_regulation of Localization of F13A1 1 5 0.45 3.12 0.57
136 INT217394 Regulation of Binding of PSEN1 1 1 0.44 1.58 0.53
137 INT188724 Gene_expression of IGLV3-1 1 29 0.75 20.88 0.51
138 INT217370 Phosphorylation of Apoe 1 2 0.63 1.8 0.49
139 INT84573 Regulation of Mavs 3 1 0.01 1.37 0.49
140 INT217393 Negative_regulation of Gene_expression of Mme 1 3 0.43 5.98 0.46
141 INT124164 Protein_catabolism of Prnp 1 20 1.00 8.58 0.44
142 INT132516 Gene_expression of NEURL 5 8 0.35 5.96 0.44
143 INT193856 Localization of Psen1 2 19 0.73 9.79 0.41
144 INT174753 Gene_expression of Apoa2 1 15 0.75 13.82 0.41
145 INT192590 Gene_expression of CA4 1 3 0.75 1.57 0.41
146 INT222645 Localization of Col4a2 1 2 0.05 0.77 0.38
147 INT217376 Regulation of Gene_expression of Syp 1 2 0.25 0.89 0.38
148 INT185964 Negative_regulation of Gene_expression of Syp 1 8 0.54 2.33 0.35
149 INT217379 Phosphorylation of Hras1 2 1 0.01 1.43 0.33
150 INT80065 Binding of Hras1 1 4 0.03 1.14 0.31
151 INT217380 Negative_regulation of Negative_regulation of Mtap2 1 2 0.27 1.18 0.31
152 INT217371 Negative_regulation of Negative_regulation of Syp 1 2 0.11 1.16 0.29
153 INT157135 Positive_regulation of MKI67 1 10 0.60 7.51 0.28
154 INT184825 Regulation of Thy1 2 7 0.42 4.14 0.28
155 INT229518 Phosphorylation of Prnp 1 5 0.69 1.62 0.27
156 INT217386 Negative_regulation of Positive_regulation of Car1 1 2 0.18 1.67 0.25
157 INT198873 Regulation of Lrp1 1 3 0.35 1.45 0.24
158 INT205148 Regulation of Gene_expression of CA4 1 1 0.09 0 0.22
159 INT188122 Negative_regulation of Hras1 1 12 0.02 8.38 0.21
160 INT198892 Regulation of Binding of Apoe 1 6 0.45 2.94 0.21
161 INT193810 Phosphorylation of APOE 1 2 0.27 1.13 0.2
162 INT165017 Gene_expression of GABPA 2 3 0.21 2.88 0.16
163 INT217387 Regulation of Abca1 1 3 0.27 2.01 0.15
164 INT204989 Gene_expression of Mavs 1 3 0.02 0.86 0.15
165 INT205142 Positive_regulation of TTBK1 1 1 0.02 0.82 0.14
166 INT183490 Regulation of Hras1 1 7 0.04 1.65 0.13
167 INT217375 Phosphorylation of Eno2 1 1 0.79 0.41 0.13
168 INT217395 Regulation of NR1H3 1 2 0.04 0.68 0.11
169 INT155667 Negative_regulation of Gene_expression of Gja1 1 3 0.42 1.16 0.1
170 INT293049 Positive_regulation of Localization of PRNP 3 1 0.07 2.67 0.09
171 INT217383 Regulation of Regulation of Mavs 1 1 0.01 0.79 0.08
172 INT318025 Gene_expression of Gjb6 1 1 0.13 0.33 0.07
173 INT205147 Regulation of Phosphorylation of APOE 1 1 0.06 0.34 0.07
174 INT318034 Binding of NEURL 2 1 0.06 1.7 0.06
175 INT217374 Positive_regulation of Regulation of Mavs 1 1 0.01 0.37 0.05
176 INT217384 Gene_expression of Laptm5 1 8 0.09 4.45 0.04
177 INT205145 Binding of TTBK1 1 1 0.01 0.12 0.03
178 INT293047 Protein_catabolism of PRNP 1 1 0.57 2 0.03
179 INT217378 Gene_expression of T(12;16)1Cje 1 1 0.30 0.27 0.03
180 INT100664 Negative_regulation of MKI67 2 12 0.10 9.77 0
181 INT217392 Negative_regulation of Binding of Bace1 2 7 0.58 1.9 0
182 INT217377 Gene_expression of Dysf 1 6 0.71 2.28 0
183 INT176092 Negative_regulation of Gene_expression of Hras1 1 5 0.03 3.31 0
184 INT217385 Regulation of Binding of Bace1 1 2 0.39 0.46 0
185 INT318035 Positive_regulation of NEURL 1 1 0.08 1.31 0
186 INT217369 Positive_regulation of Gene_expression of Apoa4 1 1 0.01 0.71 0
187 INT293048 Regulation of Protein_catabolism of PRNP 1 1 0.06 1.01 0
188 INT217391 Gene_expression of Lrp2 1 1 0.44 0.67 0
189 INT217373 Positive_regulation of Gene_expression of Lrp2 1 1 0.29 0.67 0
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