J:Acta Orthopaedica

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT318678 Atf4 Positive_regulation of Gene_expression of Ddit3 1 1 0.53 0.77 0.23
2 INT318679 Atf4 Positive_regulation of Gene_expression of Xbp1 1 1 0.53 0.77 0.23
3 INT318682 Atf4 Positive_regulation of Ddit3 1 1 0.73 1.71 0.18
4 INT318677 Xbp1 Positive_regulation of Ddit3 1 1 0.73 1.72 0.18
5 INT318680 Binding of Cebpg and Ddit3 1 1 0.39 1.73 0.18
6 INT326118 Binding of BMI1 and PCSK1 1 1 0.09 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT50058 Negative_regulation of Cpox 4 907 0.58 426.28 428.29
2 INT5374 Gene_expression of Esr1 1 412 0.77 263.89 67.34
3 INT50971 Gene_expression of Ntrk1 3 180 0.75 73.52 62.28
4 INT50970 Positive_regulation of Ntrk1 1 51 0.57 29.38 22.83
5 INT28216 Gene_expression of HRAS 5 173 0.75 93.97 20.78
6 INT12951 Negative_regulation of Cat 2 126 0.57 64.39 20.61
7 INT1703 Regulation of pCA 1 52 0.52 23.65 20.6
8 INT4067 Negative_regulation of Esr1 1 97 0.50 43.45 17.52
9 INT17237 Regulation of Esr1 1 74 0.43 49.09 17.25
10 INT12950 Gene_expression of Cat 3 85 0.75 35.94 15.76
11 INT16167 Negative_regulation of DMD 13 186 0.57 108.71 15.25
12 INT16166 Positive_regulation of DMD 1 348 0.67 133.22 15.06
13 INT171253 Positive_regulation of BMI1 1 23 0.53 39.41 11.23
14 INT165228 Binding of BMI1 5 13 0.47 25.36 7.97
15 INT80419 Gene_expression of Kdm5d 1 50 0.62 22.49 6.1
16 INT206950 Positive_regulation of Atf4 2 14 0.45 7.02 5.71
17 INT43997 Positive_regulation of Gene_expression of Esr1 1 57 0.51 36.66 5.51
18 INT13396 Gene_expression of DMD 3 125 0.75 57.81 5.45
19 INT38366 Regulation of Cat 1 45 0.62 23.45 5.34
20 INT81750 Regulation of Ntrk1 1 13 0.52 6.03 4.37
21 INT63113 Positive_regulation of HRAS 1 30 0.67 22.85 4.28
22 INT57642 Gene_expression of PCSK1 2 26 0.76 5.09 4.28
23 INT20981 Binding of HRAS 1 42 0.48 24.49 4.23
24 INT171252 Gene_expression of BMI1 1 21 0.70 26.98 4.11
25 INT80175 Positive_regulation of Gene_expression of HRAS 1 24 0.67 14.69 3.97
26 INT58602 Gene_expression of HMI 1 34 0.65 25.26 3.74
27 INT154867 Gene_expression of CECR 3 28 0.57 6.97 3.72
28 INT16165 Regulation of DMD 7 114 0.60 35.13 3.64
29 INT171998 Binding of DMD 2 58 0.47 38.13 3.35
30 INT241623 Gene_expression of Atf4 8 12 0.74 8.67 2.85
31 INT173419 Gene_expression of Ddit3 12 16 0.75 23.31 1.87
32 INT66246 Gene_expression of Mzb1 1 10 0.65 3.87 1.78
33 INT179222 Gene_expression of AMIGO2 1 7 0.66 7.68 1.77
34 INT105920 Binding of SLC9A3R2 2 5 0.36 1.99 1.75
35 INT184206 Protein_catabolism of HRAS 1 22 0.66 7.86 1.46
36 INT144671 Gene_expression of Xbp1 8 4 0.75 8.48 1.4
37 INT165800 Positive_regulation of Ddit3 2 17 0.67 11.69 1.21
38 INT32074 Positive_regulation of TAR 1 4 0.40 1.44 0.98
39 INT88032 Negative_regulation of PCSK1 1 4 0.32 1.27 0.92
40 INT72944 Positive_regulation of PCSK1 1 3 0.49 0 0.89
41 INT318665 Negative_regulation of Gene_expression of Atf4 5 1 0.56 5.16 0.85
42 INT59835 Regulation of TAR 2 3 0.23 0.58 0.8
43 INT59835 Regulation of TAR 1 3 0.23 0.58 0.8
44 INT187506 Binding of Cebpg 1 7 0.47 2.27 0.72
45 INT318666 Negative_regulation of Ddit3 6 1 0.56 6.86 0.7
46 INT318667 Negative_regulation of Gene_expression of Ddit3 5 6 0.56 3.16 0.65
47 INT241625 Regulation of Gene_expression of Atf4 1 2 0.43 0.83 0.59
48 INT306394 Negative_regulation of Kdm5d 1 1 0.02 0.49 0.49
49 INT44140 Negative_regulation of Gzmm 1 2 0.09 0.56 0.45
50 INT173418 Transcription of Ddit3 1 6 0.65 7.91 0.41
51 INT157034 Positive_regulation of Xbp1 2 2 0.45 3.44 0.38
52 INT312566 Positive_regulation of Gene_expression of CECR 1 1 0.19 1.67 0.38
53 INT173940 Positive_regulation of Negative_regulation of DMD 1 8 0.59 2.97 0.36
54 INT32073 Binding of TAR 2 4 0.26 2.37 0.36
55 INT32073 Binding of TAR 1 4 0.26 2.37 0.36
56 INT284051 Localization of MTDH 1 2 0.69 1.55 0.33
57 INT318668 Negative_regulation of Gene_expression of Xbp1 2 1 0.56 1.53 0.32
58 INT252833 Positive_regulation of Gene_expression of Ddit3 1 4 0.67 7.58 0.25
59 INT174706 Positive_regulation of Atf6 1 2 0.46 2.07 0.25
60 INT318671 Transcription of Cebpg 1 1 0.67 2.35 0.25
61 INT318676 Negative_regulation of Atf4 2 3 0.56 1.59 0.23
62 INT318675 Binding of Mst1r 1 1 0.10 1.83 0.21
63 INT318673 Negative_regulation of Xbp1 2 3 0.41 1.51 0.15
64 INT314168 Transcription of Xbp1 2 4 0.69 1.54 0.1
65 INT318674 Transcription of Atf4 2 3 0.69 1.26 0.1
66 INT173416 Localization of Ddit3 1 2 0.71 0.98 0.08
67 INT173420 Regulation of Gene_expression of Ddit3 1 2 0.37 0.84 0.07
68 INT314169 Regulation of Gene_expression of Xbp1 1 2 0.59 0.69 0.07
69 INT318670 Localization of Xbp1 1 1 0.72 0.58 0.05
70 INT318669 Localization of Atf4 1 1 0.72 0.58 0.05
71 INT318672 Positive_regulation of Transcription of Atf4 1 1 0.48 0.52 0.05
72 INT174145 Positive_regulation of EBM 1 5 0.44 0.49 0.04
73 INT232490 Binding of PCSK1 3 5 0.27 0.07 0
74 INT247976 Negative_regulation of Alm 1 2 0.04 0.66 0
75 INT166555 Positive_regulation of Tars 1 1 0.13 0 0
76 INT306395 Negative_regulation of Tars 1 1 0.06 0 0
77 INT306391 Gene_expression of Poldip3 1 1 0.17 0 0
78 INT326120 Protein_catabolism of SLC9A3R2 1 1 0.12 0.09 0
79 INT326119 Positive_regulation of Binding of PCSK1 2 1 0.37 0 0
80 INT306396 Positive_regulation of Tars 1 1 0.06 0.06 0
81 INT306397 Gene_expression of TAR 1 1 0.48 0.19 0
82 INT306390 Positive_regulation of Gene_expression of Poldip3 1 1 0.12 0 0
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