J:Acta Physiol. Scand.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT73016 PDYN Regulation of TAC1 1 1 0.29 0.34 1.54
2 INT30378 Binding of Sst and Penk 1 1 0.28 0.52 1.01
3 INT7501 Sst Positive_regulation of Gast 1 1 0.53 0 0.53
4 INT99015 Binding of Selp and Vcam1 2 1 0.27 1.76 0.35
5 INT72445 Binding of AGT and REN 3 2 0.34 0.88 0.31
6 INT99010 Selp Regulation of Vcam1 1 1 0.20 1.35 0.18
7 INT99014 Binding of Sell and Selp 1 1 0.13 1.35 0.18
8 INT99008 Regulation of Binding of Selp and Vcam1 1 1 0.33 1.36 0.18
9 INT99009 Regulation of Binding of Sell and Selp 1 1 0.15 1.36 0.18
10 INT99013 Binding of Itgb2 and Selp 1 1 0.16 1.36 0.18
11 INT99006 Regulation of Binding of Selp and Itga1 1 1 0.06 1.36 0.18
12 INT99007 Sell Regulation of Vcam1 1 1 0.12 1.35 0.18
13 INT99012 Binding of Selp and Itga1 1 1 0.05 1.36 0.18
14 INT99011 Regulation of Binding of Itgb2 and Selp 1 1 0.19 1.37 0.18
15 INT71755 Nppa Regulation of Localization of Alb 1 1 0.25 1.29 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 31 2008 0.81 518.3 1408.65
2 INT796 Gene_expression of Penk 4 1902 0.78 275.47 1057.59
3 INT1912 Gene_expression of Calca 4 1152 0.78 453.25 739.84
4 INT728 Positive_regulation of Penk 1 1068 0.70 186.9 636.87
5 INT2543 Positive_regulation of Calca 3 787 0.70 331.13 592.08
6 INT797 Regulation of Penk 2 812 0.62 111.13 542.24
7 INT443 Localization of POMC 1 1020 0.81 284.52 443.17
8 INT4758 Positive_regulation of Localization of Calca 7 557 0.70 138.55 411.04
9 INT1395 Negative_regulation of Penk 1 537 0.59 87.33 389.81
10 INT2540 Negative_regulation of Calca 1 538 0.59 172.11 384.38
11 INT6580 Negative_regulation of Ptgs1 1 929 0.59 381.53 376.26
12 INT287 Localization of Cck 5 518 0.81 86.84 364.04
13 INT2649 Regulation of Calca 5 433 0.62 146.05 330.95
14 INT477 Localization of Avp 3 813 0.81 131.58 300.4
15 INT1352 Localization of Acot1 6 728 0.80 73.01 296.01
16 INT3579 Localization of Oxt 3 555 0.81 43.35 292.44
17 INT2365 Positive_regulation of Cck 2 354 0.70 87.8 277.41
18 INT3948 Regulation of Cck 6 291 0.62 58.07 255.88
19 INT1005 Localization of Sst 5 385 0.81 26.31 244.56
20 INT1902 Gene_expression of Cck 1 348 0.78 70.33 241.92
21 INT4759 Negative_regulation of Localization of Calca 1 294 0.59 82.62 226.45
22 INT1212 Binding of Oprl1 2 312 0.48 28.6 225.15
23 INT6665 Gene_expression of FOS 1 520 0.77 165.31 217.66
24 INT4803 Transcription of Penk 3 435 0.72 59.09 182.4
25 INT1429 Gene_expression of PDYN 5 308 0.78 61.33 175.65
26 INT943 Negative_regulation of Cck 1 205 0.59 38.42 174.78
27 INT1114 Localization of Ins1 15 748 0.80 192.95 165.48
28 INT5050 Regulation of Localization of Calca 1 149 0.62 41.25 148.57
29 INT2451 Positive_regulation of Avp 2 355 0.70 102.66 147.69
30 INT1033 Positive_regulation of Ca2 1 507 0.68 131.76 147.64
31 INT2780 Regulation of Gene_expression of Penk 2 265 0.62 32.45 143.88
32 INT2541 Binding of Calca 1 200 0.48 67.14 134.62
33 INT4207 Regulation of Avp 3 267 0.62 63.72 115.33
34 INT90 Localization of Gast 6 400 0.81 137.67 113
35 INT7362 Gene_expression of Sst 1 185 0.78 41.73 111.37
36 INT5283 Positive_regulation of Npy 2 191 0.70 66.77 109.2
37 INT4936 Localization of Tacr1 1 125 0.80 35.7 107.7
38 INT9012 Localization of Vip 6 283 0.81 31.71 106.16
39 INT4742 Gene_expression of Tac1 1 177 0.78 69.99 102.66
40 INT5940 Negative_regulation of Avp 1 236 0.59 67.86 101.2
41 INT17459 Positive_regulation of Gene_expression of FOS 1 182 0.67 53.45 96.38
42 INT1004 Regulation of Sst 1 140 0.62 18.52 94.84
43 INT2862 Positive_regulation of Localization of Cck 2 108 0.70 20.75 94.25
44 INT4798 Gene_expression of Nts 1 169 0.77 29.56 86.04
45 INT2149 Positive_regulation of Oxt 3 181 0.70 24.8 85.43
46 INT5780 Regulation of Gene_expression of Calca 2 90 0.62 59.52 85.03
47 INT4857 Regulation of Tacr1 1 115 0.62 39.01 84.52
48 INT5617 Localization of Nppa 2 266 0.81 83.51 83.89
49 INT339 Regulation of Trh 6 156 0.62 39.27 83.55
50 INT4631 Positive_regulation of Sst 4 127 0.70 17.37 83.29
51 INT6107 Localization of Npy 4 180 0.81 26.76 81.67
52 INT3214 Localization of Ins1 3 527 0.80 196.9 79.26
53 INT4358 Positive_regulation of Localization of Avp 1 195 0.70 30.79 77.58
54 INT1353 Negative_regulation of Localization of Acot1 3 153 0.53 15.05 75.17
55 INT1724 Negative_regulation of ACE 2 437 0.59 315.64 74.48
56 INT5993 Positive_regulation of Nts 1 122 0.70 26.82 70.45
57 INT451 Regulation of Oxt 1 142 0.62 22.07 69.42
58 INT1988 Positive_regulation of Localization of Ins1 9 254 0.69 59.25 68.37
59 INT7344 Gene_expression of TAC1 1 132 0.75 35.48 68.26
60 INT7134 Localization of KNG1 1 127 0.79 65.73 67.97
61 INT8388 Positive_regulation of Vip 2 142 0.70 39.72 67.61
62 INT5941 Gene_expression of Oxt 1 164 0.76 22.63 65.47
63 INT3375 Gene_expression of IGHE 1 535 0.77 387.47 65.46
64 INT7280 Positive_regulation of Localization of Sst 2 97 0.70 5.64 63.37
65 INT46 Localization of Ren 2 233 0.81 46.15 62.44
66 INT8363 Localization of Nts 4 135 0.81 14.29 61.71
67 INT7884 Regulation of Localization of Oxt 2 102 0.62 7.95 61.71
68 INT1430 Regulation of PDYN 1 88 0.60 16.99 60.32
69 INT5017 Negative_regulation of Tacr1 1 76 0.58 17 57.07
70 INT8153 Regulation of Localization of Cck 2 52 0.62 11.22 54.83
71 INT771 Regulation of Nts 1 93 0.61 13.13 53.57
72 INT1456 Regulation of Oprl1 2 61 0.62 19.5 52.87
73 INT929 Positive_regulation of Oprl1 1 64 0.70 14.67 52.84
74 INT62543 Gene_expression of Icam1 5 231 0.78 187.58 52.71
75 INT5118 Regulation of SST 1 97 0.62 34.35 51.74
76 INT5338 Regulation of Npy 2 92 0.62 25.54 51.24
77 INT5098 Negative_regulation of Localization of Sst 2 70 0.58 3.56 51.17
78 INT8690 Localization of Tac1 1 71 0.80 22.98 50.75
79 INT937 Positive_regulation of Oxt 1 195 0.70 37.82 49.3
80 INT7059 Regulation of Adra2a 1 89 0.62 18.24 48.43
81 INT654 Localization of REN 4 250 0.81 75.12 47.86
82 INT6544 Negative_regulation of Localization of Cck 1 67 0.59 8.05 47.23
83 INT5337 Negative_regulation of Npy 2 87 0.59 19.6 46.75
84 INT4776 Localization of TAC1 2 82 0.78 16.89 45.21
85 INT14853 Negative_regulation of Tac1 2 80 0.59 30.87 45.06
86 INT2275 Negative_regulation of Localization of Ins1 6 183 0.59 51.02 44.94
87 INT8465 Regulation of Ptgs1 1 100 0.57 36.03 44.41
88 INT8824 Regulation of Vip 4 95 0.62 15.7 43.63
89 INT1474 Regulation of Localization of Ins1 5 132 0.61 25.96 43.07
90 INT89 Positive_regulation of Gast 7 187 0.70 80.49 42.07
91 INT30 Gene_expression of Gast 1 158 0.78 99 41.45
92 INT2531 Positive_regulation of Cebpz 1 166 0.00 43.08 38.86
93 INT4449 Positive_regulation of NA 1 179 0.55 40.26 37.82
94 INT3971 Positive_regulation of Alb 4 175 0.70 98.46 36.45
95 INT1354 Negative_regulation of Acot1 1 87 0.43 15.01 36.44
96 INT390 Positive_regulation of Agt 2 170 0.70 61.47 36.08
97 INT49 Negative_regulation of Ren 1 129 0.59 37.48 35.62
98 INT6943 Positive_regulation of Gabrd 1 71 0.70 17.36 35.25
99 INT7282 Regulation of Localization of Sst 2 58 0.62 1.92 34.83
100 INT7286 Regulation of Transcription of Penk 1 81 0.62 9.25 33.45
101 INT4727 Regulation of TAC1 2 60 0.47 6.74 32.83
102 INT1159 Negative_regulation of Agt 2 133 0.59 40.14 31.67
103 INT5069 Negative_regulation of Mthfs 1 69 0.57 22.54 31.36
104 INT5418 Negative_regulation of Alox5 1 108 0.57 42.09 31.17
105 INT10285 Binding of ADRA1D 1 102 0.47 25.82 31.11
106 INT8531 Transcription of PDYN 3 56 0.72 19.51 30.99
107 INT2278 Regulation of Localization of Gast 2 81 0.62 16.93 30.64
108 INT2229 Positive_regulation of Man2a2 1 50 0.69 7.47 30.33
109 INT1158 Regulation of Agt 1 106 0.61 29.4 30.29
110 INT28 Regulation of Gast 1 106 0.62 26.37 29.85
111 INT660 Negative_regulation of REN 1 194 0.59 82.06 29.46
112 INT91 Positive_regulation of Localization of Gast 2 96 0.70 23.22 29.36
113 INT2671 Positive_regulation of Odc1 2 82 0.70 11.03 29
114 INT2532 Negative_regulation of Cebpz 2 98 0.00 53.06 28.57
115 INT8698 Localization of Nka1 3 50 0.78 5.8 27.67
116 INT7894 Negative_regulation of Vip 3 59 0.59 11.76 27.36
117 INT97 Negative_regulation of Adrb1 1 102 0.59 32.44 26.9
118 INT19856 Gene_expression of CD8A 1 240 0.75 147.86 26.39
119 INT73670 Gene_expression of Vcam1 5 128 0.78 123.79 24.96
120 INT49141 Gene_expression of Selp 2 157 0.78 85.22 24.78
121 INT12484 Binding of Drd2 1 45 0.48 15.17 24.72
122 INT2140 Regulation of REN 2 104 0.62 28.24 24.49
123 INT18323 Negative_regulation of Localization of Ins1 2 122 0.58 45.74 23.04
124 INT11829 Negative_regulation of Odc1 1 54 0.59 7.03 23.03
125 INT825 Negative_regulation of ADRA1D 1 54 0.58 20.25 22.78
126 INT7678 Localization of Alb 4 142 0.81 80.93 22.49
127 INT7039 Regulation of Nkx1-1 1 22 0.44 10.51 20.89
128 INT3593 Gene_expression of ADRA1D 1 70 0.75 29.48 20.87
129 INT1334 Negative_regulation of Binding of Oprl1 1 29 0.59 3.03 20.62
130 INT6699 Positive_regulation of ADRA1D 1 65 0.70 22.72 20.31
131 INT7253 Negative_regulation of Localization of Gast 1 70 0.59 21.06 20.06
132 INT7017 Regulation of Npr1 1 45 0.52 3.38 20.05
133 INT11509 Localization of Slc4a4 5 66 0.67 2.34 19.05
134 INT11525 Negative_regulation of Localization of Vip 2 42 0.49 6.91 18.04
135 INT48 Positive_regulation of Localization of Ren 1 69 0.70 12.47 18.03
136 INT7644 Positive_regulation of Gene_expression of PDYN 3 27 0.69 10.19 17.47
137 INT8037 Negative_regulation of Man2a2 2 39 0.42 5.15 17.44
138 INT12875 Regulation of Adra2a 2 26 0.45 7.51 17.35
139 INT1533 Negative_regulation of AGT 1 105 0.42 46.54 16.92
140 INT15202 Regulation of Tacr1 1 26 0.60 9.65 16.48
141 INT8742 Regulation of Localization of Ins1 1 65 0.61 14.98 16.43
142 INT56447 Positive_regulation of Icam1 2 64 0.64 64.14 16.16
143 INT1261 Localization of Adh1 2 63 0.81 19.36 16.09
144 INT25517 Regulation of NFKB1 1 41 0.61 22.28 16.09
145 INT6381 Negative_regulation of Chat 2 51 0.59 19.68 15.86
146 INT3793 Regulation of CEBPZ 1 59 0.61 20.91 15.83
147 INT4719 Positive_regulation of Nka1 1 27 0.67 4.16 15.42
148 INT7523 Regulation of ADRA1D 1 42 0.45 11.63 14.52
149 INT95 Positive_regulation of Adrb1 1 34 0.62 11.95 14.41
150 INT48259 Positive_regulation of Adcyap1 2 33 0.67 10.94 14.39
151 INT11696 Gene_expression of HLA-A 1 50 0.78 41.25 14.1
152 INT5806 Regulation of Edn1 1 63 0.62 23.46 13.88
153 INT15044 Localization of Nts 2 30 0.75 4.58 13.72
154 INT3112 Regulation of Odc1 2 39 0.62 4.73 13.69
155 INT655 Positive_regulation of Localization of REN 1 86 0.70 32.41 13.56
156 INT3962 Regulation of AGT 2 50 0.62 20.96 13.01
157 INT15246 Regulation of FOS 1 32 0.60 15.34 12.94
158 INT3521 Regulation of Csf2 1 38 0.54 11.09 12.73
159 INT17811 Positive_regulation of Localization of Vip 2 35 0.67 0.85 12.67
160 INT4199 Binding of Agt 1 76 0.48 21.06 12.66
161 INT12232 Regulation of Gene_expression of PDYN 1 21 0.60 9.91 12.18
162 INT481 Regulation of Localization of Ren 1 37 0.62 5.95 11.61
163 INT5045 Regulation of VIP 1 26 0.62 7.15 11.61
164 INT398 Localization of AGT 1 45 0.78 16.97 11.54
165 INT8065 Binding of AGT 1 54 0.48 20.54 10.85
166 INT14124 Negative_regulation of Adra1a 1 34 0.59 7.48 10.85
167 INT11479 Positive_regulation of KCNMA1 1 30 0.68 10.07 10.82
168 INT348 Regulation of Adra1a 1 25 0.45 3.33 10.27
169 INT5788 Gene_expression of IL2RA 1 60 0.75 40.67 9.98
170 INT1372 Regulation of Localization of REN 2 50 0.62 5.76 9.81
171 INT4721 Negative_regulation of Nka1 1 17 0.59 2.08 9.57
172 INT73021 Gene_expression of EGR1 1 43 0.77 24.65 9.18
173 INT20664 Binding of ACE 1 60 0.48 35.27 9.16
174 INT5939 Regulation of Gene_expression of Oxt 1 27 0.51 2.84 9.1
175 INT30247 Regulation of Adrb1 1 18 0.44 4.45 8.93
176 INT1223 Negative_regulation of Snai1 4 15 0.38 2.05 8.46
177 INT5340 Negative_regulation of Positive_regulation of Npy 1 12 0.55 3.83 8.23
178 INT6384 Regulation of Eef1a1 1 21 0.61 2.95 7.97
179 INT15165 Positive_regulation of Localization of Nka1 1 7 0.66 1.19 7.78
180 INT20914 Positive_regulation of Snai1 1 13 0.41 3.41 7.69
181 INT25220 Positive_regulation of Binding of Calca 1 7 0.69 3.78 7.34
182 INT6576 Localization of Adra2a 1 11 0.71 1.49 7.18
183 INT63169 Positive_regulation of Gene_expression of Selp 1 35 0.69 21.95 7.16
184 INT60196 Binding of FOS 1 33 0.47 13.11 6.95
185 INT11747 Positive_regulation of IL2RA 1 22 0.67 16.55 6.95
186 INT4438 Negative_regulation of Localization of Adh1 2 18 0.59 6.23 6.95
187 INT8532 Regulation of Transcription of PDYN 1 10 0.44 4.97 6.95
188 INT7499 Negative_regulation of Positive_regulation of Sst 1 9 0.59 0.42 6.9
189 INT18460 Positive_regulation of Transcription of PDYN 1 11 0.67 2.14 6.61
190 INT73022 Positive_regulation of Gene_expression of EGR1 1 21 0.69 10.61 6.5
191 INT15339 Regulation of Phax 1 8 0.45 4.34 6.49
192 INT7842 Gene_expression of Adra1a 1 14 0.67 1.99 6.39
193 INT81443 Positive_regulation of Vcam1 2 29 0.63 28.4 6.35
194 INT63170 Positive_regulation of Selp 2 27 0.68 24.1 6.3
195 INT8368 Binding of Nka1 1 12 0.34 1.66 6.3
196 INT17207 Positive_regulation of Localization of Slc4a4 1 18 0.58 0.09 6.02
197 INT7765 Positive_regulation of Positive_regulation of Man2a2 1 9 0.45 1.62 5.81
198 INT3794 Regulation of CDNF 2 16 0.16 2.99 5.59
199 INT51318 Binding of Pia8 1 2 0.26 1.38 5.39
200 INT4598 Negative_regulation of Adh1 1 15 0.54 4.69 5.33
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