J:Am. J. Physiol. Gastrointest. Liver Physiol.

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT168420	Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun	1	1	0.30	0.88	0.74
2	INT168948	Binding of CCK and CCKAR	1	1	0.23	0	0.3
3	INT168947	Binding of CCK and CCL28	1	1	0.39	0	0.3
4	INT24529	Gal Regulation of Localization of Ins1	1	1	0.23	0.1	0.25
5	INT169567	IL33 Regulation of Pscs	1	1	0.03	0.46	0.19
6	INT169562	PDGFD Positive_regulation of Gene_expression of IL33	1	1	0.03	0.35	0.13
7	INT163418	Sub1 Positive_regulation of Pscs	1	1	0.07	0.23	0.12
8	INT160730	Galr2 Regulation of Localization of Ins1	1	1	0.06	0	0.08
9	INT161533	Tlr4 Regulation of Gene_expression of Tlr4	1	1	0.01	0.75	0.03
10	INT161532	Tlr4 Positive_regulation of Protein_catabolism of Nfkbia	1	1	0.00	0.76	0.03
11	INT161531	Nfkbia Regulation of Gene_expression of Tlr4	1	1	0.01	0.75	0.03
12	INT161534	Tlr4 Positive_regulation of Phosphorylation of Nfkbia	1	1	0.00	0.77	0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT18357	Gene_expression of TRPV1	2	825	0.78	307.11	382.81
2	INT6580	Negative_regulation of Ptgs1	4	929	0.59	381.53	376.26
3	INT5379	Gene_expression of Fos	5	656	0.78	255.5	292.54
4	INT9158	Gene_expression of Tnf	3	722	0.78	522.01	277.68
5	INT9381	Positive_regulation of TRPV1	9	523	0.70	187.4	276.05
6	INT738	Regulation of POMC	1	459	0.62	111.19	243.74
7	INT26472	Regulation of Oprm1	4	191	0.62	35.84	173.1
8	INT5380	Positive_regulation of Gene_expression of Fos	4	243	0.70	105.65	131.05
9	INT65054	Positive_regulation of Nfkb1	5	285	0.70	149.33	126.73
10	INT3214	Localization of Ins1	2	527	0.80	196.9	79.26
11	INT123584	Gene_expression of Trpa1	2	176	0.78	83	78.65
12	INT2431	Positive_regulation of Mpo	7	275	0.70	211.99	78.47
13	INT12476	Negative_regulation of TRPV1	1	124	0.59	47.95	77.98
14	INT98621	Regulation of Trpv1	1	121	0.62	79.24	75.23
15	INT117601	Positive_regulation of Trpa1	1	174	0.70	72.41	71.9
16	INT49995	Positive_regulation of Gene_expression of Tnf	2	187	0.70	125.07	70.54
17	INT96622	Localization of Trpv1	2	110	0.81	59.82	63.25
18	INT1951	Positive_regulation of Tlr4	1	345	0.70	176.99	62.42
19	INT8528	Negative_regulation of Gene_expression of Fos	1	100	0.59	41.15	55.6
20	INT52800	Negative_regulation of Gene_expression of Tnf	2	142	0.59	92.27	55.47
21	INT3213	Gene_expression of Ins1	5	511	0.76	357.59	53.32
22	INT9383	Localization of TRPV1	1	98	0.81	33.23	46.24
23	INT98498	Binding of Trpv1	1	75	0.48	33.67	44.4
24	INT5307	Regulation of Tnf	2	87	0.62	78.71	43.4
25	INT65536	Negative_regulation of Positive_regulation of Nfkb1	2	77	0.59	38.86	33.33
26	INT109820	Gene_expression of Trpv4	5	121	0.78	39.69	33.11
27	INT13897	Localization of Sst	2	65	0.81	14.91	32.24
28	INT96913	Positive_regulation of Mapk8	2	179	0.69	130.44	32.2
29	INT91775	Gene_expression of Slc6a4	1	102	0.78	26.45	28.23
30	INT118734	Gene_expression of Tlr4	2	70	0.78	55.7	28.19
31	INT74726	Negative_regulation of Slc6a4	1	61	0.59	21.01	27.84
32	INT6934	Binding of OPRD1	1	51	0.48	7.72	25.73
33	INT9377	Positive_regulation of Positive_regulation of TRPV1	2	43	0.70	15.81	24.47
34	INT117600	Positive_regulation of Trpm8	1	65	0.70	31.96	24.46
35	INT18400	Localization of Glp1r	14	97	0.80	11.96	24.32
36	INT45437	Localization of Acot1	1	84	0.79	17.37	22.18
37	INT7573	Positive_regulation of Nr3c2	3	38	0.67	20	21.84
38	INT7535	Negative_regulation of Tlr4	1	111	0.56	56.84	21.37
39	INT1156	Binding of CCK	1	27	0.48	8.71	20.58
40	INT8332	Positive_regulation of OPRD1	1	30	0.61	3.88	17.65
41	INT119233	Positive_regulation of Trpv4	1	65	0.70	20.21	17.3
42	INT109316	Negative_regulation of Mapk8	1	72	0.59	50.59	17.24
43	INT134596	Regulation of Trpa1	1	32	0.62	18.78	17.02
44	INT69769	Positive_regulation of Pscs	14	61	0.56	39.32	15.93
45	INT32706	Gene_expression of Cyp3a23/3a1	1	51	0.65	19.48	15.06
46	INT151120	Negative_regulation of Tlr4	1	18	0.59	21.09	14.46
47	INT51158	Positive_regulation of Tacr1	2	33	0.70	15.22	13.91
48	INT103828	Negative_regulation of Gene_expression of TRPV1	1	23	0.59	13.63	13.81
49	INT97237	Transcription of TRPV1	1	33	0.72	10.56	12.4
50	INT145515	Positive_regulation of Localization of Trpv1	1	23	0.50	10.12	12.08
51	INT5649	Negative_regulation of Positive_regulation of Mpo	1	31	0.59	26.62	11.92
52	INT148639	Gene_expression of Uchl1	1	30	0.59	16.76	11.54
53	INT96915	Phosphorylation of Mapk8	2	73	0.81	40.69	11.44
54	INT111992	Gene_expression of Pscs	10	40	0.76	27.47	10.74
55	INT81538	Phosphorylation of Nfkbia	1	27	0.62	8.86	10.49
56	INT134597	Binding of Trpa1	1	21	0.48	9.41	9.74
57	INT146346	Negative_regulation of Gene_expression of Trpa1	1	15	0.59	11.76	8.83
58	INT80872	Protein_catabolism of Nfkbia	1	28	0.92	10.56	8.62
59	INT18583	Positive_regulation of Gene_expression of Ins1	1	67	0.50	49.72	8.26
60	INT96912	Positive_regulation of Phosphorylation of Mapk8	2	29	0.69	18.33	8.14
61	INT18393	Negative_regulation of Ryr1	2	15	0.43	3.63	7.57
62	INT81532	Negative_regulation of Protein_catabolism of Nfkbia	1	21	0.54	8.92	7.38
63	INT18340	Gene_expression of CRX	1	16	0.22	13.85	7.13
64	INT47944	Positive_regulation of Localization of Glp1r	3	23	0.70	0.16	6.79
65	INT47942	Positive_regulation of Glp1r	1	38	0.70	15.94	6.47
66	INT24527	Negative_regulation of Gal	1	12	0.59	7.16	6.29
67	INT7564	Positive_regulation of Nr3c1	1	16	0.68	4.98	6.25
68	INT22017	Negative_regulation of Nts	1	11	0.43	1.89	5.64
69	INT24526	Localization of Gal	2	13	0.75	3.54	5.5
70	INT23725	Gene_expression of CCKAR	1	14	0.55	0.14	5.3
71	INT81535	Negative_regulation of Phosphorylation of Nfkbia	1	15	0.44	5.74	5.18
72	INT61452	Gene_expression of IL1RAP	1	15	0.58	7.21	5.09
73	INT116150	Positive_regulation of Ddit3	1	26	0.67	22.58	5.01
74	INT156296	Regulation of Trpv4	1	20	0.45	7.84	4.86
75	INT106524	Phosphorylation of Jun	2	23	0.80	15.35	4.78
76	INT122675	Negative_regulation of Gene_expression of Slc6a4	1	14	0.59	6.4	4.69
77	INT118565	Gene_expression of Ddit3	1	35	0.75	23.62	4.32
78	INT45433	Positive_regulation of Localization of Acot1	1	18	0.45	1.9	4.32
79	INT9378	Regulation of Positive_regulation of TRPV1	1	9	0.45	2.36	4.26
80	INT37615	Gene_expression of ESCO1	1	6	0.72	1.1	4.15
81	INT31419	Positive_regulation of Localization of Sst	2	10	0.70	0.77	3.94
82	INT133641	Binding of CCL28	1	5	0.47	3.23	3.71
83	INT31420	Regulation of Localization of Sst	1	7	0.54	0.91	3.69
84	INT13896	Negative_regulation of Localization of Sst	1	8	0.59	0.77	3.5
85	INT15299	Gene_expression of IL1RL1	1	37	0.69	10.09	3.43
86	INT68812	Regulation of Regulation of Oprm1	1	5	0.40	0.16	3.28
87	INT164920	Gene_expression of IL33	9	22	0.76	13.63	3.16
88	INT38013	Gene_expression of Casr	1	30	0.73	6.03	3.09
89	INT168745	Negative_regulation of Regulation of Trpa1	2	1	0.43	3.26	2.87
90	INT168744	Negative_regulation of Regulation of Trpv4	2	1	0.42	3.26	2.87
91	INT111516	Transcription of Mpo	1	7	0.68	7.97	2.82
92	INT167311	Gene_expression of Aqp5	4	8	0.61	1.77	2.75
93	INT160633	Gene_expression of Vdr	1	21	0.77	10.01	2.73
94	INT109822	Negative_regulation of Gene_expression of Trpv4	1	8	0.55	1.98	2.53
95	INT110284	Negative_regulation of Positive_regulation of Nr3c2	1	4	0.53	2.08	2.48
96	INT40505	Positive_regulation of CCKAR	3	3	0.40	0	2.42
97	INT122367	Positive_regulation of Positive_regulation of Tacr1	1	5	0.46	1.47	2.4
98	INT72109	Negative_regulation of Localization of Glp1r	1	8	0.59	0.8	2.3
99	INT167307	Transcription of Aqp5	4	5	0.56	0.9	2.26
100	INT168959	Gene_expression of CAV3	4	5	0.65	0.7	2.2
101	INT142740	Gene_expression of Trpv6	5	15	0.78	6.1	2.06
102	INT84806	Positive_regulation of Aqp5	3	4	0.54	0.2	1.96
103	INT22269	Gene_expression of IGKV1-5	1	32	0.50	1.71	1.95
104	INT141166	Positive_regulation of Gene_expression of Ddit3	1	15	0.56	10.32	1.92
105	INT30373	Localization of CCKAR	1	5	0.68	0.17	1.79
106	INT167309	Positive_regulation of Gene_expression of Aqp5	3	1	0.36	0.2	1.75
107	INT143664	Gene_expression of ST2	1	9	0.77	5.03	1.73
108	INT167310	Negative_regulation of Transcription of Aqp5	3	1	0.34	0.21	1.7
109	INT167308	Negative_regulation of Gene_expression of Aqp5	3	1	0.34	0.21	1.7
110	INT168964	Negative_regulation of Gene_expression of CAV3	3	1	0.47	0	1.68
111	INT22329	Gene_expression of Ptprc	3	36	0.66	15.84	1.59
112	INT18935	Positive_regulation of GER	1	9	0.69	4.91	1.5
113	INT168954	Binding of CCKAR	3	1	0.28	0	1.36
114	INT84805	Negative_regulation of Aqp5	2	4	0.43	0.35	1.24
115	INT167312	Positive_regulation of Transcription of Aqp5	2	1	0.54	0.12	1.19
116	INT24182	Gene_expression of USHBP1	1	4	0.06	1.33	1.12
117	INT135386	Localization of 4930519F16Rik	3	4	0.01	1.16	1.06
118	INT168957	Positive_regulation of CAV3	2	1	0.40	0	1.06
119	INT111517	Positive_regulation of Transcription of Mpo	1	4	0.50	4.5	1.05
120	INT168960	Binding of CAV3	2	1	0.30	0	1.05
121	INT34597	Gene_expression of Des	1	10	0.75	2.54	0.93
122	INT163939	Gene_expression of Dexi	1	1	0.06	0.92	0.81
123	INT60333	Gene_expression of CCL28	1	5	0.65	0.93	0.78
124	INT161529	Regulation of Gene_expression of Tlr4	2	3	0.45	2.7	0.69
125	INT92917	Regulation of Atp6v0a2	1	2	0.52	0.91	0.69
126	INT168965	Negative_regulation of Binding of CCKAR	1	1	0.22	0	0.63
127	INT168963	Negative_regulation of Binding of CAV3	1	1	0.30	0	0.62
128	INT168962	Positive_regulation of Localization of CAV3	1	1	0.40	0	0.62
129	INT168966	Positive_regulation of Localization of CCKAR	1	1	0.29	0	0.62
130	INT168953	Localization of CAV3	1	1	0.60	0	0.62
131	INT168475	Positive_regulation of Gene_expression of Trpv6	4	5	0.69	3.22	0.61
132	INT168955	Phosphorylation of CAV3	1	1	0.56	0	0.58
133	INT167306	Positive_regulation of Positive_regulation of Aqp5	1	1	0.36	0.07	0.58
134	INT167313	Regulation of Positive_regulation of Aqp5	1	1	0.21	0.05	0.57
135	INT167315	Negative_regulation of Transcription of TRPV1	1	1	0.36	0.08	0.55
136	INT126998	Positive_regulation of Localization of Gal	2	2	0.40	0.62	0.48
137	INT168961	Positive_regulation of Gene_expression of CLTCL1	1	1	0.14	0	0.4
138	INT168952	Positive_regulation of Gene_expression of CAV3	1	1	0.49	0	0.4
139	INT168956	Gene_expression of CLTCL1	1	1	0.19	0	0.4
140	INT161528	Localization of Tnfaip8	1	2	0.64	1.27	0.38
141	INT163417	Transcription of Pscs	2	3	0.69	0.74	0.35
142	INT168958	Regulation of Gene_expression of CCL28	1	1	0.44	0	0.31
143	INT80760	Gene_expression of TRPV5	1	4	0.75	0.73	0.25
144	INT9251	Positive_regulation of Atp6v0a2	1	3	0.45	2.83	0.21
145	INT160643	Negative_regulation of Gene_expression of Trpv6	2	2	0.58	1.45	0.15
146	INT169566	Positive_regulation of Gene_expression of IL33	1	1	0.41	0.38	0.14
147	INT169622	Regulation of Glp2r	1	1	0.27	0.08	0.14
148	INT163416	Positive_regulation of Sub1	1	2	0.25	0.52	0.12
149	INT161527	Negative_regulation of Localization of Tnfaip8	1	1	0.01	1.02	0.12
150	INT169564	Negative_regulation of Gene_expression of IL33	1	1	0.38	0.3	0.11
151	INT161526	Positive_regulation of Localization of Tnfaip8	1	1	0.01	0.95	0.09
152	INT160632	Negative_regulation of Trpv6	1	2	0.58	0.48	0.07
153	INT168476	Localization of Trpv6	1	1	0.79	0.69	0.07
154	INT168477	Regulation of Negative_regulation of Trpv6	1	1	0.45	0.48	0.07
155	INT168474	Positive_regulation of Negative_regulation of Trpv6	1	1	0.46	0.48	0.07