J:Am. J. Physiol. Gastrointest. Liver Physiol.

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 1 0.30 0.88 0.74
2 INT168948 Binding of CCK and CCKAR 1 1 0.23 0 0.3
3 INT168947 Binding of CCK and CCL28 1 1 0.39 0 0.3
4 INT24529 Gal Regulation of Localization of Ins1 1 1 0.23 0.1 0.25
5 INT169567 IL33 Regulation of Pscs 1 1 0.03 0.46 0.19
6 INT169562 PDGFD Positive_regulation of Gene_expression of IL33 1 1 0.03 0.35 0.13
7 INT163418 Sub1 Positive_regulation of Pscs 1 1 0.07 0.23 0.12
8 INT160730 Galr2 Regulation of Localization of Ins1 1 1 0.06 0 0.08
9 INT161533 Tlr4 Regulation of Gene_expression of Tlr4 1 1 0.01 0.75 0.03
10 INT161532 Tlr4 Positive_regulation of Protein_catabolism of Nfkbia 1 1 0.00 0.76 0.03
11 INT161531 Nfkbia Regulation of Gene_expression of Tlr4 1 1 0.01 0.75 0.03
12 INT161534 Tlr4 Positive_regulation of Phosphorylation of Nfkbia 1 1 0.00 0.77 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT18357 Gene_expression of TRPV1 2 825 0.78 307.11 382.81
2 INT6580 Negative_regulation of Ptgs1 4 929 0.59 381.53 376.26
3 INT5379 Gene_expression of Fos 5 656 0.78 255.5 292.54
4 INT9158 Gene_expression of Tnf 3 722 0.78 522.01 277.68
5 INT9381 Positive_regulation of TRPV1 9 523 0.70 187.4 276.05
6 INT738 Regulation of POMC 1 459 0.62 111.19 243.74
7 INT26472 Regulation of Oprm1 4 191 0.62 35.84 173.1
8 INT5380 Positive_regulation of Gene_expression of Fos 4 243 0.70 105.65 131.05
9 INT65054 Positive_regulation of Nfkb1 5 285 0.70 149.33 126.73
10 INT3214 Localization of Ins1 2 527 0.80 196.9 79.26
11 INT123584 Gene_expression of Trpa1 2 176 0.78 83 78.65
12 INT2431 Positive_regulation of Mpo 7 275 0.70 211.99 78.47
13 INT12476 Negative_regulation of TRPV1 1 124 0.59 47.95 77.98
14 INT98621 Regulation of Trpv1 1 121 0.62 79.24 75.23
15 INT117601 Positive_regulation of Trpa1 1 174 0.70 72.41 71.9
16 INT49995 Positive_regulation of Gene_expression of Tnf 2 187 0.70 125.07 70.54
17 INT96622 Localization of Trpv1 2 110 0.81 59.82 63.25
18 INT1951 Positive_regulation of Tlr4 1 345 0.70 176.99 62.42
19 INT8528 Negative_regulation of Gene_expression of Fos 1 100 0.59 41.15 55.6
20 INT52800 Negative_regulation of Gene_expression of Tnf 2 142 0.59 92.27 55.47
21 INT3213 Gene_expression of Ins1 5 511 0.76 357.59 53.32
22 INT9383 Localization of TRPV1 1 98 0.81 33.23 46.24
23 INT98498 Binding of Trpv1 1 75 0.48 33.67 44.4
24 INT5307 Regulation of Tnf 2 87 0.62 78.71 43.4
25 INT65536 Negative_regulation of Positive_regulation of Nfkb1 2 77 0.59 38.86 33.33
26 INT109820 Gene_expression of Trpv4 5 121 0.78 39.69 33.11
27 INT13897 Localization of Sst 2 65 0.81 14.91 32.24
28 INT96913 Positive_regulation of Mapk8 2 179 0.69 130.44 32.2
29 INT91775 Gene_expression of Slc6a4 1 102 0.78 26.45 28.23
30 INT118734 Gene_expression of Tlr4 2 70 0.78 55.7 28.19
31 INT74726 Negative_regulation of Slc6a4 1 61 0.59 21.01 27.84
32 INT6934 Binding of OPRD1 1 51 0.48 7.72 25.73
33 INT9377 Positive_regulation of Positive_regulation of TRPV1 2 43 0.70 15.81 24.47
34 INT117600 Positive_regulation of Trpm8 1 65 0.70 31.96 24.46
35 INT18400 Localization of Glp1r 14 97 0.80 11.96 24.32
36 INT45437 Localization of Acot1 1 84 0.79 17.37 22.18
37 INT7573 Positive_regulation of Nr3c2 3 38 0.67 20 21.84
38 INT7535 Negative_regulation of Tlr4 1 111 0.56 56.84 21.37
39 INT1156 Binding of CCK 1 27 0.48 8.71 20.58
40 INT8332 Positive_regulation of OPRD1 1 30 0.61 3.88 17.65
41 INT119233 Positive_regulation of Trpv4 1 65 0.70 20.21 17.3
42 INT109316 Negative_regulation of Mapk8 1 72 0.59 50.59 17.24
43 INT134596 Regulation of Trpa1 1 32 0.62 18.78 17.02
44 INT69769 Positive_regulation of Pscs 14 61 0.56 39.32 15.93
45 INT32706 Gene_expression of Cyp3a23/3a1 1 51 0.65 19.48 15.06
46 INT151120 Negative_regulation of Tlr4 1 18 0.59 21.09 14.46
47 INT51158 Positive_regulation of Tacr1 2 33 0.70 15.22 13.91
48 INT103828 Negative_regulation of Gene_expression of TRPV1 1 23 0.59 13.63 13.81
49 INT97237 Transcription of TRPV1 1 33 0.72 10.56 12.4
50 INT145515 Positive_regulation of Localization of Trpv1 1 23 0.50 10.12 12.08
51 INT5649 Negative_regulation of Positive_regulation of Mpo 1 31 0.59 26.62 11.92
52 INT148639 Gene_expression of Uchl1 1 30 0.59 16.76 11.54
53 INT96915 Phosphorylation of Mapk8 2 73 0.81 40.69 11.44
54 INT111992 Gene_expression of Pscs 10 40 0.76 27.47 10.74
55 INT81538 Phosphorylation of Nfkbia 1 27 0.62 8.86 10.49
56 INT134597 Binding of Trpa1 1 21 0.48 9.41 9.74
57 INT146346 Negative_regulation of Gene_expression of Trpa1 1 15 0.59 11.76 8.83
58 INT80872 Protein_catabolism of Nfkbia 1 28 0.92 10.56 8.62
59 INT18583 Positive_regulation of Gene_expression of Ins1 1 67 0.50 49.72 8.26
60 INT96912 Positive_regulation of Phosphorylation of Mapk8 2 29 0.69 18.33 8.14
61 INT18393 Negative_regulation of Ryr1 2 15 0.43 3.63 7.57
62 INT81532 Negative_regulation of Protein_catabolism of Nfkbia 1 21 0.54 8.92 7.38
63 INT18340 Gene_expression of CRX 1 16 0.22 13.85 7.13
64 INT47944 Positive_regulation of Localization of Glp1r 3 23 0.70 0.16 6.79
65 INT47942 Positive_regulation of Glp1r 1 38 0.70 15.94 6.47
66 INT24527 Negative_regulation of Gal 1 12 0.59 7.16 6.29
67 INT7564 Positive_regulation of Nr3c1 1 16 0.68 4.98 6.25
68 INT22017 Negative_regulation of Nts 1 11 0.43 1.89 5.64
69 INT24526 Localization of Gal 2 13 0.75 3.54 5.5
70 INT23725 Gene_expression of CCKAR 1 14 0.55 0.14 5.3
71 INT81535 Negative_regulation of Phosphorylation of Nfkbia 1 15 0.44 5.74 5.18
72 INT61452 Gene_expression of IL1RAP 1 15 0.58 7.21 5.09
73 INT116150 Positive_regulation of Ddit3 1 26 0.67 22.58 5.01
74 INT156296 Regulation of Trpv4 1 20 0.45 7.84 4.86
75 INT106524 Phosphorylation of Jun 2 23 0.80 15.35 4.78
76 INT122675 Negative_regulation of Gene_expression of Slc6a4 1 14 0.59 6.4 4.69
77 INT118565 Gene_expression of Ddit3 1 35 0.75 23.62 4.32
78 INT45433 Positive_regulation of Localization of Acot1 1 18 0.45 1.9 4.32
79 INT9378 Regulation of Positive_regulation of TRPV1 1 9 0.45 2.36 4.26
80 INT37615 Gene_expression of ESCO1 1 6 0.72 1.1 4.15
81 INT31419 Positive_regulation of Localization of Sst 2 10 0.70 0.77 3.94
82 INT133641 Binding of CCL28 1 5 0.47 3.23 3.71
83 INT31420 Regulation of Localization of Sst 1 7 0.54 0.91 3.69
84 INT13896 Negative_regulation of Localization of Sst 1 8 0.59 0.77 3.5
85 INT15299 Gene_expression of IL1RL1 1 37 0.69 10.09 3.43
86 INT68812 Regulation of Regulation of Oprm1 1 5 0.40 0.16 3.28
87 INT164920 Gene_expression of IL33 9 22 0.76 13.63 3.16
88 INT38013 Gene_expression of Casr 1 30 0.73 6.03 3.09
89 INT168745 Negative_regulation of Regulation of Trpa1 2 1 0.43 3.26 2.87
90 INT168744 Negative_regulation of Regulation of Trpv4 2 1 0.42 3.26 2.87
91 INT111516 Transcription of Mpo 1 7 0.68 7.97 2.82
92 INT167311 Gene_expression of Aqp5 4 8 0.61 1.77 2.75
93 INT160633 Gene_expression of Vdr 1 21 0.77 10.01 2.73
94 INT109822 Negative_regulation of Gene_expression of Trpv4 1 8 0.55 1.98 2.53
95 INT110284 Negative_regulation of Positive_regulation of Nr3c2 1 4 0.53 2.08 2.48
96 INT40505 Positive_regulation of CCKAR 3 3 0.40 0 2.42
97 INT122367 Positive_regulation of Positive_regulation of Tacr1 1 5 0.46 1.47 2.4
98 INT72109 Negative_regulation of Localization of Glp1r 1 8 0.59 0.8 2.3
99 INT167307 Transcription of Aqp5 4 5 0.56 0.9 2.26
100 INT168959 Gene_expression of CAV3 4 5 0.65 0.7 2.2
101 INT142740 Gene_expression of Trpv6 5 15 0.78 6.1 2.06
102 INT84806 Positive_regulation of Aqp5 3 4 0.54 0.2 1.96
103 INT22269 Gene_expression of IGKV1-5 1 32 0.50 1.71 1.95
104 INT141166 Positive_regulation of Gene_expression of Ddit3 1 15 0.56 10.32 1.92
105 INT30373 Localization of CCKAR 1 5 0.68 0.17 1.79
106 INT167309 Positive_regulation of Gene_expression of Aqp5 3 1 0.36 0.2 1.75
107 INT143664 Gene_expression of ST2 1 9 0.77 5.03 1.73
108 INT167310 Negative_regulation of Transcription of Aqp5 3 1 0.34 0.21 1.7
109 INT167308 Negative_regulation of Gene_expression of Aqp5 3 1 0.34 0.21 1.7
110 INT168964 Negative_regulation of Gene_expression of CAV3 3 1 0.47 0 1.68
111 INT22329 Gene_expression of Ptprc 3 36 0.66 15.84 1.59
112 INT18935 Positive_regulation of GER 1 9 0.69 4.91 1.5
113 INT168954 Binding of CCKAR 3 1 0.28 0 1.36
114 INT84805 Negative_regulation of Aqp5 2 4 0.43 0.35 1.24
115 INT167312 Positive_regulation of Transcription of Aqp5 2 1 0.54 0.12 1.19
116 INT24182 Gene_expression of USHBP1 1 4 0.06 1.33 1.12
117 INT135386 Localization of 4930519F16Rik 3 4 0.01 1.16 1.06
118 INT168957 Positive_regulation of CAV3 2 1 0.40 0 1.06
119 INT111517 Positive_regulation of Transcription of Mpo 1 4 0.50 4.5 1.05
120 INT168960 Binding of CAV3 2 1 0.30 0 1.05
121 INT34597 Gene_expression of Des 1 10 0.75 2.54 0.93
122 INT163939 Gene_expression of Dexi 1 1 0.06 0.92 0.81
123 INT60333 Gene_expression of CCL28 1 5 0.65 0.93 0.78
124 INT161529 Regulation of Gene_expression of Tlr4 2 3 0.45 2.7 0.69
125 INT92917 Regulation of Atp6v0a2 1 2 0.52 0.91 0.69
126 INT168965 Negative_regulation of Binding of CCKAR 1 1 0.22 0 0.63
127 INT168963 Negative_regulation of Binding of CAV3 1 1 0.30 0 0.62
128 INT168962 Positive_regulation of Localization of CAV3 1 1 0.40 0 0.62
129 INT168966 Positive_regulation of Localization of CCKAR 1 1 0.29 0 0.62
130 INT168953 Localization of CAV3 1 1 0.60 0 0.62
131 INT168475 Positive_regulation of Gene_expression of Trpv6 4 5 0.69 3.22 0.61
132 INT168955 Phosphorylation of CAV3 1 1 0.56 0 0.58
133 INT167306 Positive_regulation of Positive_regulation of Aqp5 1 1 0.36 0.07 0.58
134 INT167313 Regulation of Positive_regulation of Aqp5 1 1 0.21 0.05 0.57
135 INT167315 Negative_regulation of Transcription of TRPV1 1 1 0.36 0.08 0.55
136 INT126998 Positive_regulation of Localization of Gal 2 2 0.40 0.62 0.48
137 INT168961 Positive_regulation of Gene_expression of CLTCL1 1 1 0.14 0 0.4
138 INT168952 Positive_regulation of Gene_expression of CAV3 1 1 0.49 0 0.4
139 INT168956 Gene_expression of CLTCL1 1 1 0.19 0 0.4
140 INT161528 Localization of Tnfaip8 1 2 0.64 1.27 0.38
141 INT163417 Transcription of Pscs 2 3 0.69 0.74 0.35
142 INT168958 Regulation of Gene_expression of CCL28 1 1 0.44 0 0.31
143 INT80760 Gene_expression of TRPV5 1 4 0.75 0.73 0.25
144 INT9251 Positive_regulation of Atp6v0a2 1 3 0.45 2.83 0.21
145 INT160643 Negative_regulation of Gene_expression of Trpv6 2 2 0.58 1.45 0.15
146 INT169566 Positive_regulation of Gene_expression of IL33 1 1 0.41 0.38 0.14
147 INT169622 Regulation of Glp2r 1 1 0.27 0.08 0.14
148 INT163416 Positive_regulation of Sub1 1 2 0.25 0.52 0.12
149 INT161527 Negative_regulation of Localization of Tnfaip8 1 1 0.01 1.02 0.12
150 INT169564 Negative_regulation of Gene_expression of IL33 1 1 0.38 0.3 0.11
151 INT161526 Positive_regulation of Localization of Tnfaip8 1 1 0.01 0.95 0.09
152 INT160632 Negative_regulation of Trpv6 1 2 0.58 0.48 0.07
153 INT168476 Localization of Trpv6 1 1 0.79 0.69 0.07
154 INT168477 Regulation of Negative_regulation of Trpv6 1 1 0.45 0.48 0.07
155 INT168474 Positive_regulation of Negative_regulation of Trpv6 1 1 0.46 0.48 0.07
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