J:American Journal of Physiology - Endocrinology and Metabolism

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT89381 INS Positive_regulation of AKT1 6 1 0.43 3.06 0.33
2 INT164924 GIP Regulation of GYPC 1 2 0.07 0.33 0.23
3 INT164923 INS Positive_regulation of GIP 1 1 0.43 0.18 0.11
4 INT164925 GIP Positive_regulation of Localization of INS 2 1 0.59 0.86 0.09
5 INT246152 INS Regulation of S1PR2 1 1 0.02 0 0
6 INT246151 INS Negative_regulation of TXLNB 1 1 0.01 0 0
7 INT246148 INS Regulation of TXLNB 1 1 0.00 0 0
8 INT246147 AKT1 Positive_regulation of Phosphorylation of RNF123 1 1 0.01 0.09 0
9 INT246144 FBXO32 Regulation of C2 1 1 0.08 0 0
10 INT246145 INS Negative_regulation of S1PR2 1 1 0.03 0 0
11 INT246149 AKT1 Regulation of Gene_expression of RNF123 1 1 0.02 0.09 0
12 INT246150 MTRF1 Regulation of C2 1 1 0.00 0 0
13 INT246146 Regulation of INS Regulation of TXLNB 1 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT812 Localization of INS 3 1026 0.81 515.6 145.31
2 INT812 Localization of INS 2 1026 0.81 515.6 145.31
3 INT3038 Gene_expression of INS 9 1583 0.78 1174.16 107.01
4 INT1199 Positive_regulation of INS 13 579 0.70 399.64 50.43
5 INT1322 Positive_regulation of Localization of INS 1 293 0.70 120.86 45.98
6 INT1322 Positive_regulation of Localization of INS 1 293 0.70 120.86 45.98
7 INT3252 Negative_regulation of INS 2 428 0.59 271.65 39.52
8 INT89396 Phosphorylation of AKT1 8 225 0.82 111.66 19.61
9 INT97245 Gene_expression of AKT1 2 217 0.77 119.63 15.59
10 INT8210 Positive_regulation of Gene_expression of INS 1 188 0.68 146.57 12.83
11 INT4605 Negative_regulation of Gene_expression of INS 3 220 0.58 139.66 10.75
12 INT19428 Gene_expression of MTRF1 4 42 0.08 27.17 10.43
13 INT44608 Gene_expression of C2 5 45 0.75 15.84 5.05
14 INT109450 Positive_regulation of Phosphorylation of AKT1 4 62 0.64 25.18 4.21
15 INT89394 Phosphorylation of INS 1 37 0.82 35.84 3.9
16 INT194625 Gene_expression of GSK 2 18 0.75 9.02 3.23
17 INT108203 Negative_regulation of Gene_expression of AKT1 1 28 0.54 16.38 3.19
18 INT35407 Positive_regulation of C2 1 25 0.69 7.74 2.59
19 INT105993 Gene_expression of IDS 2 26 0.78 10.83 2.41
20 INT174979 Phosphorylation of GOPC 1 45 0.51 10.11 2.28
21 INT3315 Negative_regulation of Positive_regulation of INS 1 31 0.57 14.73 2.27
22 INT118791 Binding of AKT1 1 32 0.48 15.51 2.25
23 INT101866 Positive_regulation of Gene_expression of AKT1 2 49 0.52 17.47 2.14
24 INT164926 Regulation of GYPC 1 9 0.46 16.66 2.04
25 INT201683 Phosphorylation of GSK 2 15 0.80 6.6 2.01
26 INT41719 Gene_expression of MTOR 1 27 0.77 19.43 1.44
27 INT36226 Gene_expression of GIP 2 13 0.67 3.05 1.25
28 INT111277 Negative_regulation of Gene_expression of C2 1 7 0.42 2.44 1.2
29 INT135556 Localization of AKT1 3 38 0.69 12.78 1.17
30 INT183046 Transcription of INS 1 25 0.70 11.14 1.13
31 INT176147 Regulation of Phosphorylation of AKT1 1 14 0.41 6.41 1.13
32 INT130727 Regulation of C2 1 12 0.32 5.95 0.81
33 INT246180 Gene_expression of FBXO32 7 10 0.65 4.21 0.79
34 INT37289 Regulation of GIP 1 5 0.39 0.3 0.74
35 INT19427 Regulation of Gene_expression of MTRF1 1 4 0.04 1.55 0.7
36 INT246191 Transcription of GSK 1 2 0.67 0.69 0.66
37 INT217719 Positive_regulation of IDS 6 19 0.40 3.93 0.63
38 INT217723 Regulation of IDS 4 15 0.25 2.12 0.49
39 INT246182 Positive_regulation of Gene_expression of FBXO32 1 2 0.49 1.55 0.4
40 INT136180 Binding of MTOR 1 9 0.35 5.01 0.38
41 INT230244 Positive_regulation of Phosphorylation of GSK 1 4 0.49 1.43 0.36
42 INT105992 Positive_regulation of Gene_expression of IDS 1 4 0.69 0.84 0.35
43 INT41720 Positive_regulation of Gene_expression of MTOR 1 2 0.49 1.54 0.28
44 INT246186 Phosphorylation of EIF4EBP1 2 5 0.46 0.42 0.27
45 INT246201 Negative_regulation of Gene_expression of FBXO32 5 5 0.41 1.27 0.25
46 INT246173 Phosphorylation of EEF2 2 4 0.48 0.44 0.24
47 INT156204 Phosphorylation of MTOR 2 15 0.82 3.99 0.21
48 INT200666 Transcription of AKT1 1 8 0.66 4.23 0.2
49 INT239132 Negative_regulation of S1PR2 3 3 0.53 0.41 0.15
50 INT135557 Positive_regulation of Localization of AKT1 1 3 0.46 0.49 0.15
51 INT246199 Negative_regulation of Phosphorylation of GOPC 1 10 0.18 2.18 0.11
52 INT201685 Positive_regulation of Gene_expression of GSK 1 6 0.49 3.09 0.11
53 INT55891 Transcription of RPS6KB2 1 2 0.68 0.17 0.09
54 INT246196 Regulation of Gene_expression of FBXO32 1 2 0.44 0.35 0.07
55 INT246187 Positive_regulation of Negative_regulation of S1PR2 1 1 0.03 0.14 0.07
56 INT229241 Phosphorylation of RPS6KB2 2 6 0.11 1.61 0.06
57 INT246197 Regulation of Phosphorylation of FBXO32 1 1 0.27 0.14 0.06
58 INT246184 Phosphorylation of FBXO32 1 1 0.49 0.14 0.06
59 INT217732 Localization of MTOR 3 11 0.56 3.19 0.03
60 INT217730 Positive_regulation of Localization of MTOR 1 4 0.33 0.86 0
61 INT201688 Binding of GSK 1 4 0.36 1.43 0
62 INT172386 Regulation of Gene_expression of C2 1 3 0.15 0.42 0
63 INT246193 Positive_regulation of Phosphorylation of RPS6KB2 1 3 0.08 1.04 0
64 INT217731 Positive_regulation of Phosphorylation of MTOR 1 3 0.40 0.54 0
65 INT246178 Gene_expression of EIF4EBP1 1 3 0.61 1.82 0
66 INT186597 Negative_regulation of EEF2 1 3 0.25 1.36 0
67 INT246194 Regulation of Phosphorylation of MTOR 1 2 0.34 0.31 0
68 INT246198 Binding of EIF4EBP1 1 2 0.36 0.27 0
69 INT246204 Transcription of MTOR 1 1 0.25 0 0
70 INT246203 Positive_regulation of Binding of EIF4EBP1 1 1 0.03 0 0
71 INT246175 Regulation of Gene_expression of TXLNB 1 1 0.00 0 0
72 INT246183 Gene_expression of TXLNB 3 1 0.01 0 0
73 INT246177 Gene_expression of RPS6KB2 1 1 0.01 0 0
74 INT246185 Regulation of TXLNB 2 1 0.00 0.06 0
75 INT246188 Positive_regulation of Localization of EIF4EBP1 1 1 0.03 0 0
76 INT246172 Regulation of Phosphorylation of GSK 1 1 0.44 0 0
77 INT246169 Regulation of S1PR2 4 1 0.04 0.05 0
78 INT246192 Regulation of Protein_catabolism of TXLNB 1 1 0.00 0.06 0
79 INT246195 Negative_regulation of TXLNB 1 1 0.01 0 0
80 INT246179 Positive_regulation of Phosphorylation of EIF4EBP1 1 1 0.03 0.08 0
81 INT246181 Regulation of Regulation of IDS 1 1 0.01 0.09 0
82 INT246171 Regulation of Phosphorylation of EIF4EBP1 1 1 0.04 0 0
83 INT246202 Protein_catabolism of TXLNB 1 1 0.01 0.06 0
84 INT246176 Phosphorylation of TXLNB 3 1 0.01 0.08 0
85 INT246190 Localization of FBXO32 1 1 0.39 0 0
86 INT246200 Localization of EIF4EBP1 4 1 0.04 0 0
87 INT246189 Phosphorylation of RNF123 1 1 0.04 0.09 0
88 INT246170 Negative_regulation of Phosphorylation of EEF2 2 1 0.34 0 0
89 INT246174 Gene_expression of RNF123 1 1 0.05 0.09 0
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