J:Anesthesiology

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 1 0.57 1.4 0.76
2 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 1 0.17 0 0.43
3 INT149191 TNF Positive_regulation of Gene_expression of ESAM 1 1 0.47 0.68 0.33
4 INT149193 TNF Positive_regulation of Gene_expression of NFKB2 1 1 0.11 0.07 0
5 INT169858 Grin1 Regulation of Gene_expression of Grin2b 1 1 0.42 0 0
6 INT149194 TNF Positive_regulation of NFKB2 1 1 0.16 0.05 0
7 INT169856 Grin1 Positive_regulation of Grin2b 1 1 0.46 0 0
8 INT149189 Negative_regulation of TNF Positive_regulation of NFKB2 1 1 0.13 0.05 0
9 INT149190 TNF Positive_regulation of Transcription of NFKB2 1 2 0.11 0.13 0
10 INT149996 Npy6r Negative_regulation of Csk 1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 32 3083 0.78 894.43 1639.02
2 INT2542 Localization of Calca 4 2008 0.81 518.3 1408.65
3 INT6483 Gene_expression of TNF 2 3152 0.78 2515.62 929.82
4 INT1912 Gene_expression of Calca 2 1152 0.78 453.25 739.84
5 INT4758 Positive_regulation of Localization of Calca 2 557 0.70 138.55 411.04
6 INT5895 Gene_expression of Oprm1 8 525 0.78 120.67 407.29
7 INT6056 Negative_regulation of Gene_expression of Fos 12 601 0.59 193.05 386.84
8 INT2540 Negative_regulation of Calca 2 538 0.59 172.11 384.38
9 INT6580 Negative_regulation of Ptgs1 7 929 0.59 381.53 376.26
10 INT5059 Positive_regulation of TNF 1 1050 0.70 896.51 322.81
11 INT5540 Positive_regulation of Oprm1 5 344 0.70 76.77 319.71
12 INT4941 Positive_regulation of Oprd1 3 345 0.70 74.26 304.41
13 INT9158 Gene_expression of Tnf 12 722 0.78 522.01 277.68
14 INT5591 Regulation of Gene_expression of Fos 7 425 0.62 129.06 265.78
15 INT87687 Positive_regulation of Trpv1 1 409 0.70 210.24 257.59
16 INT2909 Positive_regulation of Abat 8 334 0.70 62.1 256.43
17 INT95787 Positive_regulation of Mapk1 1 568 0.70 226.51 220.94
18 INT6665 Gene_expression of FOS 12 520 0.77 165.31 217.66
19 INT22548 Positive_regulation of Casp3 2 483 0.70 258.78 213.07
20 INT6482 Positive_regulation of Gene_expression of TNF 1 659 0.70 569.88 210
21 INT2391 Negative_regulation of PTGS1 3 501 0.59 207.62 205.6
22 INT94952 Positive_regulation of Mapk14 19 305 0.70 197.83 186.61
23 INT26472 Regulation of Oprm1 3 191 0.62 35.84 173.1
24 INT5930 Positive_regulation of Oprm1 5 221 0.70 31.19 172.93
25 INT49134 Gene_expression of Grin1 13 270 0.78 84.78 148.61
26 INT13353 Positive_regulation of Tnf 3 332 0.70 248.75 148.1
27 INT3300 Positive_regulation of Gene_expression of Calca 1 179 0.70 77.76 144.2
28 INT48895 Gene_expression of Il10 7 333 0.78 221.2 138.52
29 INT60126 Regulation of Trpv1 2 186 0.62 85.53 133.4
30 INT65600 Positive_regulation of Casp3 3 376 0.70 198.44 128.03
31 INT6822 Gene_expression of Pdyn 2 215 0.78 35.99 125.76
32 INT4824 Positive_regulation of Tacr1 1 169 0.70 66.1 123.46
33 INT14151 Gene_expression of Casp3 5 311 0.78 140.26 120.68
34 INT64201 Negative_regulation of Trpv1 1 203 0.59 79.18 119.75
35 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
36 INT7341 Positive_regulation of Grin1 6 169 0.70 65.86 118.38
37 INT65731 Gene_expression of Cnr1 4 234 0.78 63.82 109.34
38 INT97701 Phosphorylation of Mapk14 9 191 0.82 115.33 100.46
39 INT17459 Positive_regulation of Gene_expression of FOS 6 182 0.67 53.45 96.38
40 INT94953 Negative_regulation of Mapk14 8 156 0.59 104.77 91.51
41 INT38731 Localization of Trpv1 1 138 0.81 52.73 90.49
42 INT1639 Negative_regulation of OPRM1 2 107 0.59 13.86 90.37
43 INT71789 Positive_regulation of MAPK1 1 396 0.70 234.44 89.27
44 INT92434 Phosphorylation of Mapk1 1 287 0.82 91.65 83.46
45 INT48406 Gene_expression of Icam1 2 277 0.78 238.28 81.71
46 INT99070 Gene_expression of Mapk14 2 147 0.78 103.99 79.59
47 INT3214 Localization of Ins1 5 527 0.80 196.9 79.26
48 INT123584 Gene_expression of Trpa1 1 176 0.78 83 78.65
49 INT1335 Negative_regulation of Oprl1 4 123 0.59 18.02 77.13
50 INT24958 Gene_expression of Nkx1-1 4 106 0.74 51.29 76.88
51 INT25363 Negative_regulation of Trpv1 1 144 0.59 64.78 75.7
52 INT98621 Regulation of Trpv1 1 121 0.62 79.24 75.23
53 INT79506 Gene_expression of Grin2b 2 122 0.78 43.71 73.42
54 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
55 INT1080 Negative_regulation of Ache 3 343 0.59 108.51 72.4
56 INT117601 Positive_regulation of Trpa1 4 174 0.70 72.41 71.9
57 INT8357 Gene_expression of KNG1 1 153 0.75 77.26 68.66
58 INT4637 Binding of Adarb1 1 132 0.41 14.48 67.76
59 INT65733 Positive_regulation of Cnr1 5 125 0.70 40.27 67.33
60 INT47690 Regulation of Bdnf 1 118 0.62 53.02 64.5
61 INT2212 Binding of Abat 1 89 0.48 18.36 63.99
62 INT96622 Localization of Trpv1 3 110 0.81 59.82 63.25
63 INT9196 Gene_expression of PTGS1 9 215 0.77 96.99 60.5
64 INT8732 Positive_regulation of Gene_expression of Oprm1 4 76 0.70 22.59 58.83
65 INT7340 Regulation of Grin1 7 87 0.62 30.37 57.93
66 INT31116 Gene_expression of Casp3 1 192 0.78 78.21 57.43
67 INT4957 Negative_regulation of Grin1 3 87 0.59 24.51 53.21
68 INT50334 Negative_regulation of Cnr1 1 84 0.58 30.86 51.75
69 INT937 Positive_regulation of Oxt 1 195 0.70 37.82 49.3
70 INT51627 Gene_expression of Grin2a 2 82 0.76 25.09 47.6
71 INT57021 Positive_regulation of Gene_expression of Grin1 2 62 0.70 24.77 47.31
72 INT71786 Phosphorylation of MAPK1 2 256 0.82 110.09 46.17
73 INT47683 Negative_regulation of Bdnf 1 92 0.59 47.53 43.55
74 INT92437 Positive_regulation of Phosphorylation of Mapk1 1 113 0.70 32.19 40.29
75 INT88081 Negative_regulation of Gene_expression of Oprm1 1 45 0.59 16.56 37.5
76 INT82054 Positive_regulation of Grin2b 1 56 0.70 17.45 37.14
77 INT63349 Gene_expression of PECAM1 1 199 0.75 166.03 36.76
78 INT3216 Positive_regulation of Localization of Ins1 1 170 0.69 56.78 35.63
79 INT48896 Positive_regulation of Gene_expression of Il10 5 73 0.70 43.14 35.5
80 INT10796 Gene_expression of CYP2B6 4 131 0.77 30.14 35.27
81 INT66005 Regulation of Cnr1 1 47 0.61 19.21 34.52
82 INT8905 Gene_expression of EDN1 5 215 0.78 157.1 34.19
83 INT57024 Regulation of Gene_expression of Grin1 3 32 0.62 9.77 32.6
84 INT62830 Gene_expression of VCAM1 2 149 0.78 125.23 32.4
85 INT86780 Positive_regulation of Hmox1 9 145 0.70 117.09 31.18
86 INT12502 Regulation of Adarb1 3 50 0.53 7.58 30.01
87 INT130837 Gene_expression of Aqp4 1 205 0.78 151.23 29.63
88 INT65598 Negative_regulation of Positive_regulation of Casp3 1 45 0.59 18.36 28.59
89 INT22211 Positive_regulation of CYP3A4 1 110 0.70 22 28.27
90 INT111359 Localization of Cnr1 1 55 0.81 11.25 27.41
91 INT7717 Positive_regulation of Adra2a 3 62 0.70 17.68 27.32
92 INT80470 Negative_regulation of Gene_expression of Grin1 2 33 0.59 10.22 27.15
93 INT72677 Regulation of Gene_expression of Oprm1 1 45 0.62 13.95 26.75
94 INT5650 Gene_expression of Mpo 1 117 0.77 80.27 26.42
95 INT276 Regulation of Ache 1 83 0.62 16.75 25.99
96 INT2040 Positive_regulation of CYP2B6 4 95 0.69 34.3 25.6
97 INT112036 Phosphorylation of Trpv1 3 51 0.82 18.59 25.6
98 INT12124 Gene_expression of MAPK1 1 141 0.75 82.4 25.58
99 INT30276 Positive_regulation of Gene_expression of Pdyn 1 39 0.67 11.28 24.89
100 INT3028 Negative_regulation of Oxt 2 76 0.58 18.52 24.4
101 INT96557 Binding of Bdnf 1 46 0.47 21.74 24.26
102 INT100124 Gene_expression of Accn3 2 38 0.78 30.02 23.63
103 INT4465 Gene_expression of CEL 2 116 0.77 98.35 23.58
104 INT99069 Positive_regulation of Gene_expression of Mapk14 1 42 0.53 29.84 23.16
105 INT18323 Negative_regulation of Localization of Ins1 3 122 0.58 45.74 23.04
106 INT1221 Regulation of SGCG 2 65 0.60 24.21 22.94
107 INT49196 Gene_expression of SELE 1 105 0.78 107.29 22.92
108 INT8248 Binding of Adra2a 2 43 0.48 6.72 22.17
109 INT60779 Negative_regulation of CYP3A 6 63 0.59 8.38 21.27
110 INT7039 Regulation of Nkx1-1 2 22 0.44 10.51 20.89
111 INT102281 Positive_regulation of Gene_expression of Grin2b 1 27 0.70 10.38 20.84
112 INT3359 Regulation of YY1 1 32 0.60 8.19 19.2
113 INT91462 Positive_regulation of Phosphorylation of MAPK1 2 99 0.67 40.28 18.99
114 INT5137 Binding of pCA 1 45 0.47 16.91 18.47
115 INT76406 Gene_expression of Hmox1 1 140 0.78 85.86 17.15
116 INT93037 Regulation of Grin2b 1 26 0.57 11.9 16.92
117 INT87932 Positive_regulation of Gene_expression of Cnr1 2 28 0.69 8.86 16.38
118 INT78697 Negative_regulation of Gene_expression of Casp3 1 33 0.57 11.22 16.16
119 INT1706 Negative_regulation of PCa 2 33 0.47 10.7 15.27
120 INT9191 Localization of EDN1 4 94 0.81 57.01 14.78
121 INT8904 Positive_regulation of Gene_expression of EDN1 3 66 0.70 65.4 14.42
122 INT7030 Regulation of Gene_expression of Pdyn 1 23 0.61 5.77 14.18
123 INT18773 Localization of ALB 1 117 0.80 69.18 13.8
124 INT111529 Phosphorylation of Mapk3 2 41 0.80 21.14 13.72
125 INT74465 Negative_regulation of Nkx1-1 2 22 0.46 8.51 13.63
126 INT104954 Negative_regulation of Positive_regulation of Mapk14 3 29 0.58 17.71 13.31
127 INT103997 Phosphorylation of Grin2a 2 17 0.64 10.75 12.67
128 INT145515 Positive_regulation of Localization of Trpv1 3 23 0.50 10.12 12.08
129 INT51625 Regulation of Gene_expression of Grin2a 1 12 0.60 3.28 11.6
130 INT73959 Positive_regulation of NOSTRIN 2 49 0.61 31.1 11.27
131 INT68290 Gene_expression of Accn1 2 32 0.73 7.36 11.23
132 INT69035 Positive_regulation of Casp1 1 43 0.69 25.18 10.67
133 INT87451 Positive_regulation of Mapk3 1 34 0.67 12.82 10.38
134 INT67915 Negative_regulation of Gtpbp4 1 18 0.33 6.31 10.17
135 INT475 Negative_regulation of Adra1a 1 28 0.58 7.87 9.83
136 INT80110 Regulation of Positive_regulation of TNF 1 34 0.44 25.79 9.78
137 INT80006 Regulation of Gene_expression of Grin2b 1 8 0.57 3.75 9.62
138 INT72148 Positive_regulation of Prkce 2 17 0.68 5.06 9.44
139 INT94196 Negative_regulation of Phosphorylation of MAPK1 3 60 0.59 31.64 9.16
140 INT146241 Positive_regulation of Gene_expression of Trpa1 1 23 0.69 8.07 8.74
141 INT2225 Binding of Gfap 1 31 0.47 11.78 8.53
142 INT15308 Localization of Chat 2 29 0.81 2.35 8.47
143 INT48404 Regulation of Gene_expression of Icam1 2 21 0.62 15.1 7.81
144 INT159750 Negative_regulation of Gene_expression of Mapk14 1 15 0.40 10.88 7.81
145 INT69033 Negative_regulation of Casp1 3 21 0.58 13.15 7.52
146 INT9802 Positive_regulation of Mtr 1 9 0.60 3.69 7.43
147 INT81293 Positive_regulation of Gene_expression of Hmox1 1 53 0.70 41.54 7.25
148 INT110104 Localization of Prkce 4 17 0.79 3.75 6.92
149 INT12838 Gene_expression of SIGMAR1 2 30 0.78 3.52 6.81
150 INT100926 Positive_regulation of Gene_expression of Grin2a 1 11 0.63 3.24 6.41
151 INT90077 Gene_expression of Casp1 2 29 0.76 20.79 6.26
152 INT101497 Phosphorylation of Prkce 4 9 0.81 2.55 5.59
153 INT14598 Gene_expression of Tpsab1 1 40 0.73 14.55 5.4
154 INT18772 Positive_regulation of Gene_expression of CYP2B6 1 14 0.49 2.93 5.4
155 INT12250 Negative_regulation of Mtr 1 19 0.50 6.9 5.35
156 INT113516 Negative_regulation of Fas 1 16 0.51 8.37 5.32
157 INT62822 Positive_regulation of Gene_expression of SELE 1 22 0.66 28.04 4.97
158 INT134610 Positive_regulation of Phosphorylation of Trpv1 1 9 0.69 4.51 4.74
159 INT149197 Negative_regulation of NFKB2 1 14 0.25 10.55 4.46
160 INT62821 Negative_regulation of Gene_expression of VCAM1 2 21 0.54 12.24 4.41
161 INT111535 Negative_regulation of Phosphorylation of Mapk3 1 9 0.57 6.39 4.31
162 INT168479 Binding of BAG3 4 13 0.36 10.68 4.21
163 INT159119 Negative_regulation of Car1 1 17 0.37 6.6 4.01
164 INT103999 Positive_regulation of Phosphorylation of Grin2a 1 5 0.38 3.12 3.94
165 INT111514 Positive_regulation of Gene_expression of Mpo 1 20 0.49 15.13 3.88
166 INT57397 Binding of Aif1 1 15 0.28 4.06 3.49
167 INT30181 Gene_expression of Adra2b 3 10 0.62 1.89 3.48
168 INT9578 Regulation of Binding of Adarb1 1 4 0.09 0.21 3.37
169 INT80779 Positive_regulation of Hbb-ar 1 10 0.41 2.48 3.29
170 INT68812 Regulation of Regulation of Oprm1 1 5 0.40 0.16 3.28
171 INT165821 Positive_regulation of Aqp4 1 27 0.70 24.37 3.22
172 INT114263 Negative_regulation of Negative_regulation of Trpv1 1 6 0.43 2.71 2.92
173 INT45503 Binding of EPO 1 42 0.48 24.85 2.88
174 INT143551 Binding of KCNA1 3 13 0.46 8.81 2.81
175 INT96901 Regulation of Negative_regulation of Mapk14 1 3 0.45 4.07 2.79
176 INT49653 Gene_expression of NFKB2 1 12 0.61 9.51 2.73
177 INT100014 Negative_regulation of Gene_expression of EDN1 1 17 0.42 7.85 2.71
178 INT115070 Binding of Accn3 1 4 0.47 3.8 2.7
179 INT76713 Regulation of Gene_expression of PECAM1 1 16 0.40 14.52 2.51
180 INT74064 Gene_expression of SPG21 1 9 0.75 4.14 2.45
181 INT127104 Regulation of P2rx6 1 4 0.23 2.71 2.22
182 INT127777 Positive_regulation of Mthfr 1 4 0.38 3.8 2.09
183 INT49253 Regulation of Gene_expression of EDN1 2 11 0.61 3.92 2.07
184 INT142049 Regulation of Mthfr 1 6 0.41 4.73 2
185 INT49259 Regulation of Localization of EDN1 1 8 0.61 6.29 1.92
186 INT40479 Negative_regulation of SIGMAR1 1 6 0.52 1.26 1.88
187 INT151520 Negative_regulation of Slc6a9 3 5 0.58 1.86 1.86
188 INT159242 Gene_expression of Slep1 2 1 0.28 0 1.8
189 INT149994 Gene_expression of Mapk3 4 16 0.65 3.45 1.62
190 INT71260 Regulation of Tpsab1 4 3 0.27 0.9 1.53
191 INT2153 Negative_regulation of Positive_regulation of Oxt 1 9 0.42 1.14 1.52
192 INT131763 Gene_expression of Gucy1b2 1 4 0.21 2.45 1.51
193 INT62820 Gene_expression of ESAM 1 8 0.76 3.2 1.41
194 INT110099 Positive_regulation of Localization of Prkce 4 4 0.68 1.3 1.25
195 INT91914 Binding of Accn1 1 3 0.36 0.44 1.24
196 INT129374 Negative_regulation of Regulation of Oprm1 1 3 0.43 0.58 1.18
197 INT62911 Regulation of Regulation of SGCG 1 3 0.44 0.53 1.16
198 INT106690 Positive_regulation of Gene_expression of SIGMAR1 1 5 0.61 0.12 1.03
199 INT138509 Negative_regulation of Gucy1b2 1 2 0.12 0.09 0.97
200 INT76472 Gene_expression of Dntt 2 14 0.65 8.51 0.95
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