J:Archives of Drug Information

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT294710 CRP Positive_regulation of Gene_expression of IL6 1 5 0.63 1.9 1.12
2 INT287494 CRP Positive_regulation of Gene_expression of CCL2 2 4 0.30 2.33 0.83
3 INT294708 CRP Positive_regulation of Gene_expression of VCAM1 2 1 0.31 1.92 0.56
4 INT294709 IRF6 Positive_regulation of Gene_expression of CCL2 1 2 0.08 0.14 0.28
5 INT228984 CRP Positive_regulation of IL6 2 1 0.63 0.99 0.17
6 INT294711 CRP Regulation of CCL2 1 1 0.12 0 0.09
7 INT294712 CRP Regulation of IL6 1 1 0.41 0 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9238 Gene_expression of IL6 25 1575 0.78 1135.66 424.22
2 INT10832 Gene_expression of IL8 3 1050 0.78 698.72 270
3 INT10194 Positive_regulation of IL6 2 702 0.70 600.62 183.38
4 INT55879 Gene_expression of CCL2 24 421 0.78 240.74 166.02
5 INT17612 Gene_expression of CRP 8 676 0.78 580.61 119.03
6 INT12339 Localization of IL8 2 437 0.81 251.87 117.39
7 INT11051 Positive_regulation of Gene_expression of IL6 8 415 0.69 319.21 109.3
8 INT12082 Localization of IL6 1 365 0.81 241.78 105.78
9 INT18009 Positive_regulation of CRP 2 518 0.70 553.03 103.74
10 INT48408 Gene_expression of ICAM1 1 494 0.78 340.08 88.6
11 INT15514 Negative_regulation of Crp 1 275 0.59 194.6 64.86
12 INT67981 Positive_regulation of CCL2 1 165 0.70 136.84 61.85
13 INT48901 Negative_regulation of IL6 1 186 0.57 136.33 57.87
14 INT9234 Negative_regulation of Gene_expression of IL6 7 171 0.59 101.61 53.15
15 INT50405 Negative_regulation of CYP3A4 1 238 0.59 53.65 51.51
16 INT9210 Regulation of IL6 1 166 0.62 125.61 49.95
17 INT22454 Regulation of Crp 4 213 0.62 160.67 49.24
18 INT81498 Positive_regulation of Gene_expression of CCL2 5 107 0.70 53.89 45.22
19 INT52732 Negative_regulation of CRP 4 169 0.59 138.47 40.33
20 INT63349 Gene_expression of PECAM1 1 199 0.75 166.03 36.76
21 INT9239 Regulation of Gene_expression of IL6 2 106 0.61 75.24 36.53
22 INT65698 Localization of CCL2 4 118 0.81 77.54 32.69
23 INT62830 Gene_expression of VCAM1 2 149 0.78 125.23 32.4
24 INT77652 Negative_regulation of Gene_expression of IL8 1 99 0.59 67.57 30.21
25 INT50230 Positive_regulation of Localization of IL6 1 105 0.70 69.21 29.52
26 INT22045 Gene_expression of IRF6 1 158 0.75 58.07 27.81
27 INT12129 Gene_expression of CYP3A4 1 107 0.78 23.11 27.6
28 INT100861 Binding of CRP 1 179 0.48 175.2 26.45
29 INT130176 Positive_regulation of Gene_expression of CRP 1 125 0.66 137.06 25.9
30 INT23257 Regulation of CRP 1 127 0.62 100.05 21.87
31 INT55880 Negative_regulation of Gene_expression of CCL2 3 49 0.59 22.37 18.09
32 INT55878 Regulation of Gene_expression of CCL2 3 34 0.62 15.71 17.97
33 INT50579 Binding of CYP3A4 1 84 0.48 17.52 17.45
34 INT167964 Gene_expression of Aes 1 30 0.58 25.41 10.16
35 INT83450 Positive_regulation of Localization of CCL2 1 28 0.70 22.14 9.83
36 INT14301 Binding of CSF2 2 82 0.48 67.95 8.98
37 INT153300 Negative_regulation of Gene_expression of CRP 3 48 0.58 39.97 7.58
38 INT52180 Binding of Aes 1 38 0.42 23.16 6.7
39 INT76096 Positive_regulation of Gene_expression of IRF6 1 37 0.49 14.24 6.39
40 INT96851 Negative_regulation of Localization of CCL2 1 14 0.53 5.98 4.57
41 INT104221 Regulation of Gene_expression of CRP 1 30 0.45 20.01 4.07
42 INT68695 Gene_expression of HTT 1 63 0.77 44.54 3.69
43 INT57728 Regulation of LDLR 1 25 0.41 13.18 3.46
44 INT46088 Localization of F3 1 15 0.37 13.7 2.23
45 INT78889 Binding of UGT1A1 1 10 0.47 3.41 1.47
46 INT155042 Gene_expression of SHFM1 1 25 0.65 4.57 0.94
47 INT17574 Binding of CISH 1 23 0.31 4.3 0.93
48 INT68692 Regulation of HTT 1 8 0.60 4.06 0.89
49 INT121336 Positive_regulation of HTT 1 10 0.45 10.88 0.59
50 INT270790 Negative_regulation of Binding of CRP 1 5 0.42 2.9 0.55
51 INT185370 Gene_expression of ANC 10 28 0.65 13.28 0.4
52 INT61611 Positive_regulation of ANC 1 17 0.41 4.43 0.31
53 INT286241 Negative_regulation of Gene_expression of Aes 1 1 0.04 0.64 0.31
54 INT185372 Negative_regulation of ANC 2 6 0.26 1.52 0.03
55 INT264247 Positive_regulation of Gene_expression of ANC 3 5 0.38 1.71 0
56 INT276084 Positive_regulation of Negative_regulation of ANC 1 1 0.13 0.2 0
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