J:BMC Biochem

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 1 0.35 13.11 3.11
2 INT223424 Binding of Rnpep and Lta4h 1 2 0.02 0.37 0.19
3 INT217478 Binding of Tnfrsf11a and Traf6 1 4 0.39 1.22 0.17
4 INT217470 Traf6 Positive_regulation of Ngf 1 1 0.36 0.52 0.1
5 INT217476 Nup62 Positive_regulation of Ngf 1 1 0.37 0.52 0.1
6 INT217477 Traf6 Positive_regulation of Binding of Nup62 1 1 0.32 0.47 0.09
7 INT170330 'Regulation of ' Regulation of Gene_expression of Ido1 1 1 0.01 0.38 0.08
8 INT217486 Binding of PDB1 and Sqstm1 1 1 0.03 1.19 0.08
9 INT217472 Binding of Nup62 and Mul1 1 1 0.12 0 0.05
10 INT217471 Binding of Nup62 and Traf6 1 1 0.26 0 0.05
11 INT217468 Positive_regulation of Binding of Nup62 and Mul1 1 1 0.16 0 0.05
12 INT217467 Binding of Nup62 and Tnfrsf11a 1 1 0.31 0 0.05
13 INT217474 Tnfrsf11a Regulation of Gene_expression of Tnfsf11 1 1 0.41 1.2 0.04
14 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 1 0.01 0.13 0.04
15 INT223425 Binding of Npepo and LOC360919 1 1 0.00 0 0.03
16 INT170337 Gene_expression of Ido1 Positive_regulation of MRXS5 1 1 0.01 0.12 0.03
17 INT170326 Ido1 Positive_regulation of Cpox 1 1 0.07 0.12 0.03
18 INT170338 Gene_expression of Ido1 Positive_regulation of IGHD2-15 1 1 0.02 0.12 0.03
19 INT170327 Ido1 Positive_regulation of Gene_expression of Cpox 1 1 0.07 0.12 0.03
20 INT223426 Binding of Rnpep and Npepo 1 1 0.00 0 0.03
21 INT170329 Binding of Col4a1 and Col1a1 1 1 0.03 0.14 0.03
22 INT170331 Binding of Col7a1 and Col1a1 1 1 0.00 0.14 0.03
23 INT170210 Binding of CETP and HSD11B1 1 2 0.17 2.58 0
24 INT217473 Nup62 Regulation of Tnfrsf11a 1 1 0.38 0.66 0
25 INT170236 Lpl Regulation of HSD11B1 1 1 0.04 0.98 0
26 INT223428 Binding of Cndp2 and Rnpep 1 4 0.02 0 0
27 INT170213 CETP Positive_regulation of Gene_expression of HSD11B1 1 1 0.21 1.49 0
28 INT217487 Binding of PDB1 and Tnfrsf11a 1 1 0.03 0.76 0
29 INT217480 Tnfsf11 Negative_regulation of Tnfrsf11a 1 1 0.39 0.75 0
30 INT170212 Gene_expression of PLTP Positive_regulation of HSD11B1 1 2 0.12 3.01 0
31 INT170214 PLTP Positive_regulation of HSD11B1 1 1 0.11 1.34 0
32 INT170215 CETP Positive_regulation of HSD11B1 1 1 0.26 1.35 0
33 INT170211 Binding of HSD11B1 and LPL 1 1 0.02 1.47 0
34 INT170237 Lpl Regulation of CETP 1 1 0.02 0.99 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT49441 Negative_regulation of Cpox 2 494 0.59 303.22 177.46
2 INT120811 Gene_expression of Gopc 4 1174 0.59 428.49 150.55
3 INT49439 Gene_expression of Cpox 23 508 0.73 326.97 130.17
4 INT170332 Gene_expression of IFN1@ 1 477 0.75 275.21 69.65
5 INT96937 Gene_expression of Mmp9 2 191 0.75 150.3 56.01
6 INT170646 Negative_regulation of Fig4 1 213 0.37 81.29 46.92
7 INT223416 Gene_expression of Trhde 1 2 0.48 64.16 34.21
8 INT67039 Positive_regulation of Cpox 7 144 0.65 98.4 33.77
9 INT93534 Gene_expression of Tnfsf11 1 185 0.77 119.26 33.66
10 INT6660 Positive_regulation of Jun 1 148 0.69 67.58 29.73
11 INT140193 Gene_expression of Mmp3 1 58 0.71 49.65 25.4
12 INT9886 Gene_expression of Ptgs1 1 92 0.77 40.66 25.31
13 INT86295 Gene_expression of Mmp2 1 114 0.76 73.68 24.25
14 INT8640 Positive_regulation of HSD11B1 2 332 0.67 377.84 22.36
15 INT69993 Positive_regulation of Gene_expression of Cpox 3 93 0.55 69.4 22.05
16 INT170313 Gene_expression of Mmp1a 4 50 0.65 38.53 21.36
17 INT7561 Positive_regulation of gr 7 70 0.57 31.92 20.22
18 INT116282 Gene_expression of Mmp13 4 83 0.75 45.4 20.18
19 INT10565 Gene_expression of MRXS5 1 94 0.53 37.35 19.08
20 INT78990 Regulation of Cpox 10 72 0.57 35.22 18.16
21 INT170308 Gene_expression of Ido1 98 159 0.75 69.51 15.98
22 INT170335 Gene_expression of INCENP 1 176 0.54 91.62 15.31
23 INT53080 Positive_regulation of Ptgs1 1 42 0.42 23.58 14.37
24 INT1735 Gene_expression of HSD11B1 11 199 0.75 257.87 11.5
25 INT83611 Negative_regulation of Gene_expression of Cpox 1 55 0.29 31.09 11.5
26 INT93533 Positive_regulation of Tnfsf11 1 53 0.50 36.93 10.53
27 INT79720 Positive_regulation of Cat 4 57 0.70 31.81 10.11
28 INT170333 Binding of IFN1@ 1 68 0.47 49.01 9.72
29 INT61264 Regulation of Jun 1 36 0.61 18.42 8.71
30 INT171962 Gene_expression of Tnfrsf11a 8 40 0.72 31.1 7.84
31 INT170295 Positive_regulation of Ido1 10 40 0.67 28.89 7.61
32 INT119729 Binding of Tnfsf11 1 31 0.35 24.02 7.45
33 INT8101 Binding of INCENP 1 42 0.31 16.2 6.68
34 INT98310 Regulation of gr 1 21 0.39 15.04 6.68
35 INT60713 Binding of Col7a1 1 47 0.43 22.52 6.29
36 INT136555 Negative_regulation of Tnfsf11 1 31 0.55 22.23 6.23
37 INT17086 Binding of HSD11B1 2 84 0.47 122.28 6.16
38 INT170315 Positive_regulation of Gene_expression of Ido1 26 50 0.67 25.39 6.06
39 INT170296 Regulation of Gene_expression of Gopc 1 33 0.38 12.49 6
40 INT63822 Gene_expression of Mmp23 2 23 0.43 14.15 5.96
41 INT113700 Positive_regulation of Chuk 1 30 0.41 21.17 5.69
42 INT85653 Regulation of Gene_expression of Cpox 5 24 0.24 20.55 5.22
43 INT170311 Negative_regulation of Ido1 5 16 0.48 14.47 4.81
44 INT99905 Negative_regulation of Negative_regulation of Cpox 1 11 0.35 7.01 4.37
45 INT6661 Positive_regulation of Positive_regulation of Jun 1 31 0.50 7.12 3.89
46 INT3183 Negative_regulation of MRXS5 1 15 0.41 6.56 3.45
47 INT63820 Gene_expression of Mmp7 1 14 0.77 10.37 3.44
48 INT116281 Negative_regulation of Gene_expression of Mmp13 1 15 0.41 9.96 3.41
49 INT18617 Gene_expression of Npepo 1 13 0.58 4.78 3.39
50 INT34977 Gene_expression of Hmga2 6 11 0.76 12.39 3.07
51 INT171959 Binding of Tnfrsf11a 3 15 0.34 11.03 3.02
52 INT170324 Negative_regulation of Gene_expression of Mmp1a 2 8 0.13 6.28 2.94
53 INT170305 Regulation of Gene_expression of Mmp9 2 11 0.33 5.7 2.8
54 INT49759 Negative_regulation of CETP 2 43 0.58 52 2.68
55 INT12051 Negative_regulation of Rnpep 5 7 0.36 0.42 2.59
56 INT194748 Positive_regulation of Nfatc1 1 16 0.64 5.07 2.44
57 INT108245 Gene_expression of Lpo 4 9 0.67 2.55 2.42
58 INT144490 Regulation of Gene_expression of Tnfsf11 1 14 0.58 14.09 2.39
59 INT170323 Regulation of Gene_expression of Ido1 11 11 0.60 8.74 2.33
60 INT92835 Gene_expression of Col4a1 8 22 0.49 13.5 2.27
61 INT55090 Positive_regulation of Wnt7a 3 13 0.37 2.25 2.2
62 INT217447 Positive_regulation of Positive_regulation of Nfatc1 1 4 0.46 3.34 2.2
63 INT45176 Negative_regulation of LPL 1 34 0.59 22.22 2.01
64 INT58432 Positive_regulation of Gsr 1 12 0.70 9.4 1.94
65 INT29844 Regulation of Lpo 1 3 0.42 0.77 1.94
66 INT164270 Gene_expression of Lta4h 3 4 0.59 3.13 1.84
67 INT111534 Regulation of Nfatc1 1 11 0.29 2.11 1.77
68 INT41986 Positive_regulation of Gene_expression of HSD11B1 6 26 0.49 32.84 1.52
69 INT24458 Negative_regulation of PDB1 1 8 0.41 4.5 1.5
70 INT143716 Phosphorylation of Chuk 1 16 0.41 5.25 1.35
71 INT95668 Positive_regulation of Tnfrsf11a 3 12 0.47 10.14 1.34
72 INT217438 Binding of Chuk 1 24 0.25 7.29 1.29
73 INT11871 Gene_expression of Rnpep 21 4 0.23 1.88 1.29
74 INT170294 Regulation of Gene_expression of Mmp13 1 5 0.44 4.25 1.26
75 INT82248 Positive_regulation of Regulation of Cpox 1 4 0.44 2.57 1.19
76 INT36461 Regulation of Col4a1 1 10 0.26 5.43 1.17
77 INT147909 Gene_expression of Lpl 4 21 0.58 9.35 1.14
78 INT16669 Gene_expression of CNDP2 1 8 0.26 1.7 1.12
79 INT170319 Regulation of Gene_expression of Mmp1a 2 5 0.11 2.72 1.11
80 INT170317 Protein_catabolism of Cpox 2 4 0.15 0.43 1.1
81 INT170321 Binding of Mmp13 1 3 0.36 2.54 1.09
82 INT153769 Negative_regulation of Tnfrsf11a 1 4 0.39 2.13 1.05
83 INT52113 Gene_expression of CETP 5 25 0.69 25.71 0.99
84 INT170939 Positive_regulation of Lpo 13 14 0.65 4.59 0.98
85 INT39012 Positive_regulation of Rnpep 1 3 0.44 0.09 0.98
86 INT29846 Negative_regulation of Lpo 4 3 0.55 1.94 0.78
87 INT108253 Positive_regulation of Gene_expression of Lpo 4 2 0.47 1.19 0.75
88 INT127432 Gene_expression of Nup62 9 20 0.71 11.01 0.71
89 INT28958 Negative_regulation of Wnt7a 1 3 0.45 0.49 0.65
90 INT217442 Regulation of Sqstm1 2 3 0.59 3.86 0.65
91 INT89100 Gene_expression of CNOT1 1 7 0.65 1.76 0.59
92 INT143713 Positive_regulation of Phosphorylation of Chuk 2 4 0.25 1.38 0.58
93 INT95670 Regulation of PDB1 2 4 0.60 5.59 0.55
94 INT158678 Positive_regulation of Lta4h 1 2 0.33 0.55 0.55
95 INT170306 Gene_expression of Mmp11 1 1 0.06 0.95 0.54
96 INT124774 Binding of Vcp 2 4 0.44 3.4 0.52
97 INT84880 Regulation of Rnpep 1 3 0.34 0.15 0.52
98 INT93017 Binding of PDB1 1 8 0.36 6.36 0.51
99 INT170299 Negative_regulation of Gene_expression of Ido1 13 12 0.57 2.59 0.5
100 INT24459 Positive_regulation of PDB1 2 7 0.46 7 0.5
101 INT170314 Positive_regulation of Gene_expression of Col4a1 4 7 0.18 3.52 0.49
102 INT170208 Negative_regulation of Lpl 1 15 0.49 6.07 0.45
103 INT170334 Gene_expression of IGHD2-15 2 3 0.14 0.75 0.44
104 INT217452 Binding of Nup62 5 1 0.38 2.7 0.44
105 INT155775 Gene_expression of PDB1 8 12 0.65 10.18 0.41
106 INT170318 Regulation of Ido1 3 6 0.38 2.63 0.38
107 INT71907 Gene_expression of Clone C2 1 2 0.16 0.12 0.38
108 INT217464 Binding of Traf6 2 5 0.29 1.28 0.35
109 INT170316 Transcription of Mmp3 2 3 0.63 0.67 0.34
110 INT118264 Binding of Hmbs 1 6 0.37 4.87 0.33
111 INT170312 Regulation of Transcription of Mmp3 2 1 0.46 0.34 0.27
112 INT158458 Regulation of Gene_expression of Mmp23 2 4 0.02 1.73 0.25
113 INT152145 Regulation of Gene_expression of Mmp7 1 2 0.61 1.07 0.25
114 INT217446 Negative_regulation of Binding of Nup62 3 1 0.33 1.54 0.25
115 INT170229 Gene_expression of PLTP 6 9 0.77 21.32 0.24
116 INT116724 Positive_regulation of Gene_expression of CETP 1 3 0.41 7.92 0.23
117 INT159112 Transcription of MT1F 1 2 0.60 0.71 0.23
118 INT170304 Gene_expression of Mmp10 1 1 0.31 0.47 0.23
119 INT70647 Regulation of CETP 1 7 0.61 4.53 0.21
120 INT155776 Positive_regulation of Gene_expression of PDB1 2 2 0.17 1.56 0.18
121 INT217463 Positive_regulation of Nup62 1 5 0.39 1.79 0.17
122 INT170937 Positive_regulation of Positive_regulation of Lpo 2 3 0.44 0.62 0.16
123 INT217448 Regulation of Tnfrsf11a 3 1 0.42 2.31 0.14
124 INT217454 Positive_regulation of Gene_expression of Nup62 1 2 0.39 1.56 0.11
125 INT170320 Binding of Ido1 1 1 0.36 0.19 0.11
126 INT170307 Regulation of Gene_expression of Col4a1 1 2 0.16 1.45 0.1
127 INT170297 Positive_regulation of Regulation of Ido1 1 1 0.39 0.29 0.1
128 INT170234 Positive_regulation of Gene_expression of PLTP 3 4 0.69 10.56 0.08
129 INT127433 Negative_regulation of Gene_expression of Nup62 2 2 0.53 2.36 0.08
130 INT170298 Regulation of Gene_expression of Hmga2 3 1 0.01 0.48 0.08
131 INT170309 Regulation of Class II promoter 2 1 0.01 0.68 0.08
132 INT217461 Negative_regulation of Positive_regulation of Nup62 1 1 0.33 0.41 0.07
133 INT170300 Positive_regulation of Gene_expression of Hmga2 1 2 0.68 4.51 0.06
134 INT170302 Regulation of Hmga2 1 2 0.44 0.94 0.06
135 INT217443 Regulation of Nup62 4 1 0.48 1.47 0.05
136 INT217453 Regulation of Positive_regulation of Tnfrsf11a 1 1 0.42 0.38 0.05
137 INT217465 Regulation of Positive_regulation of PDB1 1 1 0.04 0.69 0.05
138 INT223420 Binding of Rnpep 4 1 0.03 0 0.04
139 INT170336 Negative_regulation of Gene_expression of IGHD2-15 1 1 0.02 0.15 0.04
140 INT217458 Protein_catabolism of Ubc 1 1 0.10 0.19 0.03
141 INT170322 Gene_expression of Adam19 1 1 0.13 0.06 0.03
142 INT170228 Negative_regulation of PLTP 1 3 0.43 4.67 0
143 INT170209 Positive_regulation of Gene_expression of Lpl 1 2 0.29 1.59 0
144 INT217457 Negative_regulation of Nup62 1 2 0.33 0.94 0
145 INT223419 Gene_expression of Rbm3 1 1 0.01 0 0
146 INT217445 Positive_regulation of Binding of Sqstm1 1 1 0.48 0.39 0
147 INT223422 Localization of Lta4h 1 1 0.50 0 0
148 INT170301 Negative_regulation of Negative_regulation of Ido1 1 1 0.36 0.32 0
149 INT170310 Transcription of Ido1 2 1 0.61 0.52 0
150 INT223418 Negative_regulation of Lta4h 1 1 0.28 0 0
151 INT223417 Binding of Rbm3 1 1 0.01 0 0
152 INT217466 Negative_regulation of Gene_expression of PDB1 2 1 0.04 1.56 0
153 INT217459 Regulation of Gene_expression of Nup62 1 1 0.35 0.35 0
154 INT217444 Binding of Sqstm1 1 1 0.46 0.38 0
155 INT170938 Regulation of Positive_regulation of Lpo 1 1 0.42 0.31 0
156 INT297603 Binding of Chit1 1 1 0.35 0 0
157 INT223414 Negative_regulation of Negative_regulation of Rnpep 1 1 0.02 0 0
158 INT223415 Negative_regulation of Negative_regulation of Lta4h 1 1 0.28 0 0
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