J:BMC Biol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT248172 Epo Regulation of Cysltr1 1 1 0.01 0.74 0.63
2 INT248170 Epo Regulation of Ltp 1 1 0.11 0.74 0.62
3 INT248173 Car2 Positive_regulation of GRIN1 1 1 0.08 0 0.22
4 INT248171 Epo Regulation of Sult1a1 1 1 0.08 0.11 0.21
5 INT261690 Binding of GSC and TCF23 1 4 0.10 0 0.12
6 INT261691 Binding of TFAM and TCF23 1 1 0.01 0 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT796 Gene_expression of Penk 16 1902 0.78 275.47 1057.59
2 INT7114 Positive_regulation of Ltp 2 1192 0.62 290.76 755.77
3 INT58061 Gene_expression of Trpv1 5 1117 0.78 451.54 637.59
4 INT728 Positive_regulation of Penk 1 1068 0.70 186.9 636.87
5 INT797 Regulation of Penk 1 812 0.62 111.13 542.24
6 INT64202 Positive_regulation of Trpv1 2 643 0.70 249.66 397.42
7 INT5540 Positive_regulation of Oprm1 1 344 0.70 76.77 319.71
8 INT1665 Positive_regulation of Pag1 1 270 0.68 186.63 229.87
9 INT6665 Gene_expression of FOS 5 520 0.77 165.31 217.66
10 INT2391 Negative_regulation of PTGS1 1 501 0.59 207.62 205.6
11 INT798 Positive_regulation of Gene_expression of Penk 9 394 0.70 78.53 203.07
12 INT4803 Transcription of Penk 5 435 0.72 59.09 182.4
13 INT89054 Positive_regulation of Gene_expression of Trpv1 1 156 0.70 90.78 102.03
14 INT1351 Gene_expression of Pag1 3 131 0.57 89.48 98.76
15 INT17459 Positive_regulation of Gene_expression of FOS 3 182 0.67 53.45 96.38
16 INT6490 Negative_regulation of ADCY1 2 145 0.58 26.25 70.96
17 INT5861 Gene_expression of Egr1 5 203 0.78 49.35 68.13
18 INT6926 Regulation of Pag1 3 72 0.39 55.79 65.09
19 INT5573 Negative_regulation of Gene_expression of Penk 3 113 0.59 21.83 64.66
20 INT20964 Gene_expression of OPRK1 1 96 0.78 23.54 58.18
21 INT5356 Positive_regulation of FOS 6 153 0.69 54.21 56.74
22 INT7287 Positive_regulation of Transcription of Penk 3 103 0.70 19.81 50.37
23 INT29105 Positive_regulation of OPRK1 1 68 0.70 7.06 44.69
24 INT17561 Localization of Car2 1 303 0.79 60.95 44.52
25 INT7828 Positive_regulation of Oprd1 1 55 0.69 14.11 42.86
26 INT5130 Regulation of GNRH1 1 139 0.62 31.95 42.08
27 INT58062 Negative_regulation of Gene_expression of Trpv1 1 66 0.59 22.34 38.02
28 INT5862 Positive_regulation of Egr1 3 82 0.70 30.4 33.96
29 INT33768 Positive_regulation of Cysltr1 1 87 0.46 54.66 33.52
30 INT6683 Gene_expression of Drd2 1 64 0.78 11.31 32.28
31 INT22939 Gene_expression of Csf2 3 164 0.78 85.1 32.22
32 INT4459 Positive_regulation of Arc 3 74 0.69 33.61 28.29
33 INT73314 Gene_expression of Arc 5 133 0.78 67.78 27.44
34 INT6054 Positive_regulation of Gene_expression of Egr1 3 67 0.70 18.45 25.93
35 INT13334 Gene_expression of Drd1a 1 43 0.62 7.73 24.43
36 INT19580 Binding of Pag1 1 24 0.30 15.13 20.88
37 INT7290 Negative_regulation of Transcription of Penk 2 33 0.59 7.28 16.5
38 INT197375 Gene_expression of Car1 3 84 0.65 16.46 16.45
39 INT47708 Gene_expression of Nr4a1 4 30 0.78 5.12 13.59
40 INT20881 Negative_regulation of OPRK1 2 20 0.43 3.73 13.37
41 INT3521 Regulation of Csf2 2 38 0.54 11.09 12.73
42 INT42459 Positive_regulation of Gene_expression of Pag1 1 19 0.25 13.49 12.22
43 INT82950 Positive_regulation of Gdnf 2 36 0.51 11.72 10.5
44 INT14881 Gene_expression of Car3 1 49 0.73 14.89 9.94
45 INT123040 Phosphorylation of Grk4 2 12 0.60 0.31 9.14
46 INT47701 Positive_regulation of Nr4a1 5 26 0.70 4.45 8.64
47 INT119940 Positive_regulation of Gene_expression of Arc 3 36 0.70 18.87 7.85
48 INT6055 Transcription of Egr1 2 47 0.69 3.61 7.68
49 INT52152 Gene_expression of Insig1 9 18 0.63 2.55 7.34
50 INT133237 Gene_expression of Homer1 5 19 0.78 6.39 7.05
51 INT68279 Positive_regulation of Gene_expression of Csf2 1 30 0.67 16.31 6.88
52 INT5847 Transcription of FOS 1 31 0.69 11.11 6.41
53 INT84779 Positive_regulation of Hcrt 1 9 0.70 1.27 6.21
54 INT3520 Binding of Csf2 1 27 0.43 9.68 6.08
55 INT90752 Positive_regulation of Gene_expression of Nr4a1 1 13 0.70 2.83 5.53
56 INT85683 Regulation of Gpbar1 4 16 0.60 3.3 5.5
57 INT160853 Gene_expression of Syp 1 87 0.72 20.06 5.31
58 INT131625 Binding of Gpbar1 1 7 0.17 2.9 5.23
59 INT86488 Gene_expression of Kcnc1 1 34 0.66 3.58 4.72
60 INT51944 Positive_regulation of Transcription of Egr1 1 12 0.49 1.96 4.72
61 INT18639 Positive_regulation of OAP 1 16 0.69 10.49 4.57
62 INT54911 Localization of FOS 1 20 0.78 3.27 4.56
63 INT97391 Binding of Lep 1 18 0.48 8.97 4.47
64 INT77148 Gene_expression of Kcna1 5 20 0.73 4.08 4.46
65 INT133234 Positive_regulation of Gene_expression of Homer1 4 10 0.70 4.22 4.43
66 INT181244 Gene_expression of ZBTB32 19 20 0.59 0.56 4.33
67 INT133235 Positive_regulation of Homer1 1 8 0.70 3.22 3.9
68 INT106095 Localization of Arc 1 17 0.80 7.61 3.74
69 INT33661 Regulation of Tbpl1 1 7 0.44 5.36 3.26
70 INT261712 Regulation of GABRB3 1 6 0.09 3.03 3.14
71 INT181246 Positive_regulation of ZBTB32 12 13 0.61 1.37 2.85
72 INT245671 Positive_regulation of Gene_expression of Car1 2 15 0.28 4.31 2.67
73 INT181219 Positive_regulation of Phosphorylation of Grk4 1 4 0.30 0.05 2.42
74 INT144366 Negative_regulation of Positive_regulation of Gdnf 1 4 0.41 1.43 2.41
75 INT85684 Phosphorylation of Gpbar1 1 7 0.79 0.7 2.39
76 INT48980 Positive_regulation of Transcription of FOS 1 10 0.67 3.07 2.34
77 INT47700 Transcription of Nr4a1 2 9 0.69 1.37 2.25
78 INT70522 Binding of Kcna1 5 2 0.36 0.73 2.22
79 INT146491 Binding of Adrbk1 2 3 0.48 1.58 2.09
80 INT218608 Negative_regulation of Swap70 3 4 0.17 5.69 1.95
81 INT133240 Transcription of Homer1 1 5 0.71 1.57 1.89
82 INT181238 Binding of ZBTB32 6 7 0.42 2.22 1.77
83 INT207861 Positive_regulation of Gene_expression of Insig1 4 7 0.05 1.25 1.69
84 INT144993 Gene_expression of Epor 2 4 0.75 5.7 1.61
85 INT148237 Positive_regulation of Tbpl1 1 4 0.49 2.05 1.59
86 INT72329 Transcription of Arc 1 20 0.67 12.52 1.51
87 INT178029 Gene_expression of Epo 4 25 0.76 14.98 1.46
88 INT181240 Regulation of ZBTB32 6 1 0.29 0 1.37
89 INT181243 Localization of ZBTB32 7 1 0.49 0 1.32
90 INT11203 Gene_expression of BCR 2 30 0.75 33.49 1.22
91 INT178023 Regulation of Epo 7 11 0.45 3.87 1.22
92 INT145943 Negative_regulation of Gpbar1 1 6 0.40 1.96 1.21
93 INT86486 Negative_regulation of Gene_expression of Kcna1 2 4 0.55 1.74 1.21
94 INT218609 Localization of Kcna1 4 1 0.78 0 1.15
95 INT59768 Regulation of TFAM 1 7 0.45 4.64 1.08
96 INT36580 Positive_regulation of LCN1 1 9 0.45 5.63 1.02
97 INT73450 Gene_expression of Pilra 1 7 0.05 2.87 0.97
98 INT178026 Positive_regulation of Epo 2 12 0.70 8.14 0.95
99 INT113144 Positive_regulation of Transcription of Nr4a1 1 3 0.59 1.05 0.89
100 INT181239 Positive_regulation of Gene_expression of ZBTB32 4 1 0.45 0 0.85
101 INT37113 Positive_regulation of Sult1a1 1 3 0.44 0.81 0.75
102 INT183399 Gene_expression of Cyp2b10 1 17 0.39 18.39 0.71
103 INT6050 Localization of Egr1 1 4 0.68 0.53 0.7
104 INT47699 Negative_regulation of Positive_regulation of Nr4a1 1 2 0.43 0 0.67
105 INT113145 Localization of Nr4a1 1 2 0.74 0.17 0.63
106 INT176407 Positive_regulation of MIER1 1 2 0.45 1.49 0.62
107 INT181242 Negative_regulation of ZBTB32 2 1 0.24 0 0.62
108 INT248166 Protein_catabolism of Epo 1 1 0.89 0.71 0.59
109 INT218605 Negative_regulation of Kcna2 1 2 0.41 1.68 0.55
110 INT218612 Negative_regulation of Kcna3 2 1 0.01 0.68 0.54
111 INT231296 Gene_expression of Syn1 2 8 0.23 0.65 0.49
112 INT197369 Regulation of Gene_expression of Car1 1 4 0.24 0.25 0.47
113 INT81322 Negative_regulation of GPR83 1 2 0.42 0.83 0.46
114 INT218611 Gene_expression of Kcna3 1 1 0.02 0.34 0.26
115 INT181221 Binding of Grk4 1 1 0.09 0 0.24
116 INT248168 Positive_regulation of Transcription of Epor 1 1 0.36 0 0.19
117 INT248169 Positive_regulation of Transcription of Epo 1 1 0.50 0 0.19
118 INT248165 Transcription of Epo 1 1 0.69 0 0.19
119 INT248167 Transcription of Epor 1 1 0.49 0 0.19
120 INT200796 Negative_regulation of Epo 1 7 0.43 3.22 0.18
121 INT192748 Localization of BCR 1 4 0.68 2.4 0.18
122 INT207862 Localization of Homer1 1 2 0.26 0.1 0.17
123 INT181241 Regulation of Positive_regulation of ZBTB32 2 1 0.29 0 0.14
124 INT181237 Negative_regulation of Negative_regulation of OPRK1 1 1 0.07 0 0.14
125 INT181222 Phosphorylation of Adrbk1 1 1 0.16 0 0.14
126 INT207860 Negative_regulation of Gene_expression of Homer1 1 1 0.15 0 0.12
127 INT348287 Binding of Dgkb 1 1 0.35 0.27 0.12
128 INT261711 Binding of GSC 4 1 0.32 0 0.11
129 INT218607 Regulation of Kcna2 1 1 0.38 0.29 0.08
130 INT218610 Transcription of Kcna1 1 1 0.51 1.05 0.07
131 INT218606 Regulation of Transcription of Kcna1 1 1 0.26 1.05 0.07
132 INT181245 Phosphorylation of ZBTB32 1 1 0.46 0 0.05
133 INT207864 Positive_regulation of Positive_regulation of MIER1 1 1 0.45 0 0.04
134 INT207863 Positive_regulation of Transcription of MIER1 1 1 0.49 0 0.04
135 INT207865 Transcription of MIER1 1 1 0.67 0 0.04
136 INT181247 Negative_regulation of Regulation of ZBTB32 1 1 0.24 0 0.03
137 INT261706 Regulation of Binding of GSC 1 1 0.34 0 0.03
138 INT261705 Binding of TCF23 7 1 0.15 1.09 0.03
139 INT261708 Regulation of Binding of TCF23 1 1 0.14 0 0.03
140 INT193210 Gene_expression of TCF23 1 2 0.46 0.44 0
141 INT261713 Regulation of GSC 1 2 0.34 0.91 0
142 INT247975 Gene_expression of Alm 2 2 0.07 1.31 0
143 INT261709 Protein_catabolism of ADRM1 2 1 0.13 0.5 0
144 INT261710 Phosphorylation of ADRM1 1 1 0.08 0.44 0
145 INT181220 Negative_regulation of Binding of Adrbk1 1 1 0.11 0 0
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