J:BMC Clin Pharmacol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT183269 Binding of CEBPB and CPOX 1 1 0.07 1.61 0.89
2 INT198382 Binding of AR and SRD5A1 2 1 0.06 0.84 0.17
3 INT188249 PLAT Positive_regulation of PLG 2 1 0.10 0.86 0.14
4 INT339020 SERPINA1 Negative_regulation of ELANE 1 1 0.07 0.59 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 1 3152 0.78 2515.62 929.82
2 INT49750 Negative_regulation of CPOX 1 735 0.58 360.06 274.19
3 INT1562 Localization of Crh 1 499 0.81 126.74 236.68
4 INT2391 Negative_regulation of PTGS1 2 501 0.59 207.62 205.6
5 INT50670 Gene_expression of CPOX 2 763 0.76 442.13 195.02
6 INT1114 Localization of Ins1 9 748 0.80 192.95 165.48
7 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
8 INT252 Localization of GH1 4 529 0.80 227.4 122.05
9 INT397 Localization of SST 1 232 0.81 58.05 101.19
10 INT1472 Positive_regulation of Ins1 1 349 0.69 146.2 86.36
11 INT914 Positive_regulation of GH1 1 292 0.69 100.7 84.91
12 INT3657 Gene_expression of Ins1 4 514 0.78 321.69 75.76
13 INT1988 Positive_regulation of Localization of Ins1 2 254 0.69 59.25 68.37
14 INT546 Binding of ALB 6 311 0.48 85.98 60.14
15 INT50672 Positive_regulation of CPOX 2 205 0.44 125.93 60.06
16 INT55344 Gene_expression of Ros1 1 396 0.54 217.64 59.98
17 INT1200 Negative_regulation of Ins1 1 274 0.58 155.17 56.14
18 INT2276 Regulation of Ins1 1 234 0.61 103.78 54.05
19 INT921 Regulation of GH1 1 172 0.60 52.88 51.04
20 INT531 Gene_expression of GH1 3 376 0.75 193.45 46.24
21 INT2275 Negative_regulation of Localization of Ins1 2 183 0.59 51.02 44.94
22 INT1474 Regulation of Localization of Ins1 1 132 0.61 25.96 43.07
23 INT4004 Gene_expression of IGHG3 1 321 0.71 221.03 42.33
24 INT5973 Regulation of IL1B 2 109 0.62 66.6 39.88
25 INT16323 Gene_expression of pr 4 62 0.66 36.14 38.26
26 INT56870 Gene_expression of CYP2D6 1 87 0.78 8.83 37.53
27 INT985 Negative_regulation of GH1 1 213 0.57 89.53 32.39
28 INT10797 Binding of CYP2D6 1 86 0.48 15.09 31.16
29 INT177581 Regulation of Fig4 1 113 0.41 39.26 27.75
30 INT2609 Localization of ELANE 1 111 0.81 50.22 26.63
31 INT64175 Negative_regulation of Gene_expression of CPOX 1 66 0.38 39.64 23.07
32 INT16303 Negative_regulation of Localization of GH1 3 89 0.59 37.31 22.15
33 INT5905 Negative_regulation of ELANE 1 113 0.59 47.43 22.09
34 INT16396 Negative_regulation of CEBPZ 2 76 0.48 30.03 21.6
35 INT72060 Positive_regulation of Gene_expression of Ros1 1 127 0.41 76.76 20.91
36 INT106097 Localization of pr 4 20 0.62 12.01 19.46
37 INT81194 Binding of CPOX 1 40 0.29 23.7 18.95
38 INT9197 Binding of PTGS1 1 44 0.48 18.48 16.26
39 INT3400 Positive_regulation of pr 1 57 0.68 36.9 16.24
40 INT102680 Protein_catabolism of COL7A1 2 49 0.69 34.68 15.78
41 INT615 Regulation of Alb 1 66 0.62 33.43 15.33
42 INT86383 Negative_regulation of EGFR 1 258 0.59 173.94 13.32
43 INT41313 Gene_expression of Gpx1 1 68 0.78 34.24 11.77
44 INT158070 Localization of Aes 1 23 0.65 19.93 10.9
45 INT167964 Gene_expression of Aes 3 30 0.58 25.41 10.16
46 INT10049 Negative_regulation of SERPINA1 2 56 0.59 44.52 9.93
47 INT4391 Gene_expression of SERPINA1 6 47 0.78 41.43 9.7
48 INT102987 Regulation of MMP3 1 23 0.60 9.35 9.54
49 INT52924 Negative_regulation of GSR 3 49 0.58 28.08 9.28
50 INT130731 Protein_catabolism of COL2A1 2 47 0.96 21.86 9.28
51 INT93490 Gene_expression of GPM6A 1 14 0.69 3.14 9.08
52 INT860 Regulation of ALB 1 48 0.60 25.11 8.95
53 INT55597 Negative_regulation of Gpx1 4 59 0.55 28.3 8.83
54 INT185691 Positive_regulation of WDTC1 5 24 0.48 12.57 6.49
55 INT210326 Binding of DDOST 2 6 0.48 4.27 6.26
56 INT91159 Negative_regulation of Ros1 1 35 0.44 26.12 5.97
57 INT188844 Gene_expression of AES 1 44 0.58 33.94 5.85
58 INT10980 Gene_expression of GYPA 1 40 0.78 15.32 5.51
59 INT92330 Gene_expression of WDTC1 5 22 0.47 13.12 5.15
60 INT201130 Localization of AES 2 31 0.63 25.45 5.12
61 INT156794 Gene_expression of CISH 1 41 0.58 23.09 5.03
62 INT11298 Gene_expression of Ido1 9 6 0.58 6.71 4.85
63 INT143557 Positive_regulation of Ido1 1 6 0.40 5.34 4.8
64 INT24412 Localization of WDTC1 1 18 0.68 12.45 4.5
65 INT9842 Binding of F2 1 36 0.47 22.79 4.42
66 INT189629 Negative_regulation of TIMP3 2 14 0.48 7.63 3.91
67 INT124655 Negative_regulation of PECAM1 1 13 0.23 10.32 3.78
68 INT25464 Binding of SAA1 1 11 0.42 6.89 3.72
69 INT53584 Regulation of Gpx1 1 19 0.62 14.38 3.48
70 INT101068 Negative_regulation of CDCP1 1 27 0.03 17.67 3.45
71 INT91070 Regulation of GSR 1 27 0.59 16.64 3.42
72 INT130729 Negative_regulation of Protein_catabolism of COL2A1 1 15 0.42 7.59 3.35
73 INT200443 Positive_regulation of AES 1 27 0.60 22.46 3.22
74 INT117348 Regulation of EGFR 1 75 0.61 47.73 3.09
75 INT16616 Negative_regulation of SRD5A1 5 44 0.57 34.81 2.96
76 INT54938 Regulation of Rb1 1 6 0.44 4.41 2.69
77 INT120515 Gene_expression of Otc 1 13 0.66 4.33 2.6
78 INT10048 Positive_regulation of SERPINA1 2 11 0.68 8.59 2.43
79 INT210324 Localization of DDOST 2 3 0.65 1.78 2.4
80 INT188255 Gene_expression of DKK1 3 19 0.60 12.69 2.39
81 INT31134 Regulation of Binding of ALB 1 13 0.62 2.51 2.37
82 INT113438 Positive_regulation of GPM6A 1 3 0.11 3.26 2.29
83 INT150248 Positive_regulation of Gene_expression of Ido1 2 2 0.43 2.68 1.77
84 INT86250 Regulation of WDTC1 4 11 0.31 4.2 1.64
85 INT24415 Negative_regulation of WDTC1 1 8 0.57 2.66 1.47
86 INT179379 Positive_regulation of Positive_regulation of GPM6A 1 1 0.07 0.58 1.37
87 INT71304 Binding of CEBPB 1 3 0.36 2.69 1.32
88 INT120722 Gene_expression of TYMP 24 35 0.75 19.26 1.31
89 INT198387 Regulation of SRD5A1 1 2 0.60 1.29 1.26
90 INT1867 Positive_regulation of GABBR1 1 6 0.69 0.55 1.18
91 INT77123 Binding of WDTC1 2 6 0.26 3.36 1.16
92 INT185687 Protein_catabolism of WDTC1 1 4 0.46 2.62 1.1
93 INT120514 Negative_regulation of Gene_expression of Otc 1 4 0.41 1.19 1.08
94 INT131116 Localization of IGKV1-5 2 10 0.36 2.13 1.06
95 INT179380 Regulation of ABCB7 1 1 0.26 0.27 1.04
96 INT15186 Negative_regulation of HRH2 1 8 0.51 2.26 0.99
97 INT210325 Positive_regulation of Localization of DDOST 1 1 0.31 0.39 0.97
98 INT221967 Protein_catabolism of C2 2 2 0.08 1.06 0.83
99 INT135836 Negative_regulation of Sod1 1 5 0.25 1.62 0.82
100 INT253278 Regulation of Coro6 1 1 0.02 0.75 0.81
101 INT188251 Localization of DKK1 1 6 0.50 3.26 0.77
102 INT79169 Binding of PLG 1 10 0.47 5.88 0.72
103 INT114246 Positive_regulation of Negative_regulation of EGFR 1 13 0.49 8.67 0.7
104 INT46392 Regulation of SERPINA1 1 4 0.44 2.23 0.68
105 INT184445 Binding of Adamts1 1 7 0.38 1.24 0.61
106 INT327116 Positive_regulation of Localization of AES 1 4 0.22 2.69 0.55
107 INT311099 Positive_regulation of Negative_regulation of TIMP3 1 2 0.22 0.78 0.45
108 INT203568 Regulation of SKP2 2 3 0.26 1.61 0.38
109 INT165472 Localization of CTSC 1 2 0.68 0.38 0.38
110 INT311098 Binding of ADAMTS5 1 1 0.04 0.45 0.36
111 INT311100 Binding of ADAMTS1 1 1 0.47 0.45 0.35
112 INT138556 Positive_regulation of TYMP 23 23 0.58 12.9 0.28
113 INT116703 Negative_regulation of Negative_regulation of Gpx1 1 3 0.18 0.81 0.28
114 INT37570 Localization of Otc 1 2 0.61 0.97 0.25
115 INT211375 Regulation of Gene_expression of TYMP 3 2 0.43 2.44 0.22
116 INT57278 Localization of SERPINA1 1 4 0.81 2.59 0.21
117 INT228916 Transcription of spc 1 2 0.30 1.62 0.18
118 INT177568 Localization of Gpx1 2 5 0.49 1.82 0.16
119 INT180626 Gene_expression of spc 3 6 0.34 6.83 0.15
120 INT174575 Gene_expression of LAD1 2 1 0.04 0 0.13
121 INT177582 Regulation of Sod1 1 2 0.24 0.39 0.1
122 INT127144 Regulation of CD82 3 5 0.35 0.6 0.09
123 INT198389 Negative_regulation of SRD5A2 2 1 0.01 0.76 0.09
124 INT188250 Positive_regulation of RPS6KA1 1 1 0.45 0.42 0.09
125 INT188252 Positive_regulation of DKK1 2 4 0.41 2.94 0.08
126 INT211376 Positive_regulation of Gene_expression of TYMP 2 3 0.67 1.3 0.07
127 INT211378 Negative_regulation of TYMP 1 2 0.56 1.45 0.07
128 INT145370 Transcription of DKK1 1 3 0.53 1.07 0.05
129 INT183275 Positive_regulation of Regulation of EGFR 1 1 0.36 0.21 0.05
130 INT178534 Positive_regulation of SRD5A1 1 2 0.44 1.23 0
131 INT174577 Positive_regulation of CD82 1 2 0.03 0.24 0
132 INT142587 Regulation of TYMP 5 2 0.51 2 0
133 INT174574 Regulation of TAL1 1 2 0.01 1.62 0
134 INT174576 Binding of LAD1 2 1 0.03 0 0
135 INT188254 Gene_expression of RPS6KA1 3 1 0.70 1.35 0
136 INT211377 Negative_regulation of Gene_expression of TYMP 4 1 0.56 0.7 0
137 INT211374 Regulation of Positive_regulation of TYMP 1 1 0.23 0.65 0
138 INT203567 Transcription of WDTC1 1 1 0.06 0.07 0
139 INT183274 Negative_regulation of STK39 1 1 0.04 0.41 0
140 INT176004 Transcription of PCMTD2 1 1 0.26 0 0
141 INT188253 Localization of RPS6KA1 1 1 0.67 0.87 0
142 INT211379 Positive_regulation of Positive_regulation of TYMP 1 1 0.39 0.13 0
143 INT203566 Negative_regulation of Gene_expression of WDTC1 2 1 0.04 0.33 0
144 INT198388 Negative_regulation of SCG5 1 1 0.57 0.49 0
145 INT339026 Phosphorylation of SERPINA1 1 1 0.56 0.47 0
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