J:BMC Genet

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT212815 WAS Positive_regulation of CNR1 1 1 0.01 0.62 1.16
2 INT212824 WAS Positive_regulation of Cnr1 1 1 0.21 0.62 1.16
3 INT311612 Binding of Drd2 and Sert1 1 1 0.12 0.65 0.86
4 INT178334 Binding of Pon1 and Chdh 1 17 0.11 11.45 0.66
5 INT170558 Binding of Myoc and Narf 1 2 0.04 3.03 0.63
6 INT197050 Binding of HLA-DOA and HLA-E 2 2 0.08 1.73 0.58
7 INT48848 Binding of HLA-B and HLA-E 3 1 0.34 1.95 0.45
8 INT311616 Binding of MET and Comt 1 1 0.01 0.2 0.37
9 INT170560 Binding of Renbp and Narf 1 1 0.01 1.69 0.27
10 INT311613 Binding of Slc6a4 and Pten 1 1 0.24 0.32 0.21
11 INT178336 Binding of SUGT1 and Chdh 1 2 0.00 0.98 0.17
12 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 1 0.02 1.07 0.16
13 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 1 0.02 1.07 0.16
14 INT254434 Binding of Lrp5 and Best1 3 2 0.29 2.53 0
15 INT170885 Binding of PRSS1 and RHBDD2 1 1 0.01 0.4 0
16 INT207031 Binding of HLA-C and HLA-E 1 2 0.35 0.1 0
17 INT171598 Binding of APOB and Lipg 1 1 0.01 0.63 0
18 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 1 0.53 0.98 0
19 INT342387 Binding of CALCR and Car1 1 1 0.11 0.83 0
20 INT235596 HNF4A Regulation of Gene_expression of TPI1 1 1 0.00 0.25 0
21 INT342378 Binding of Vdr and Best1 1 1 0.05 0.4 0
22 INT171599 Binding of APOC3 and Sst1 1 2 0.01 0.68 0
23 INT342383 Binding of Srp14 and Best1 1 1 0.00 0.56 0
24 INT170562 Car2 Regulation of Narf 1 1 0.05 1.17 0
25 INT171600 INCENP Negative_regulation of Lipg 1 1 0.00 0.38 0
26 INT170559 Narf Regulation of Gene_expression of Car2 1 1 0.05 1.01 0
27 INT185468 Fabp6 Regulation of Abcg5 1 1 0.00 0.44 0
28 INT342381 Binding of Lrp5 and Vdr 1 1 0.55 0.97 0
29 INT171601 INCENP Negative_regulation of Lpl 1 1 0.01 0.38 0
30 INT342382 Binding of Car1 and Lrp5 1 1 0.40 0.9 0
31 INT342388 Binding of CALCR and Vdr 1 1 0.12 0.83 0
32 INT213751 Binding of FUT2 and ISCA1 1 1 0.00 0.16 0
33 INT171602 APOC3 Negative_regulation of Lipg 1 1 0.04 0.38 0
34 INT342379 Binding of Car1 and Sugt1 1 1 0.01 0.83 0
35 INT342386 Binding of CALCR and Best1 1 2 0.01 0.96 0
36 INT171603 APOC3 Negative_regulation of Lpl 1 1 0.48 0.38 0
37 INT170561 Renbp Regulation of Narf 1 3 0.01 3.86 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT9659 Gene_expression of Il6 1 991 0.78 715.11 265.57
2 INT62124 Gene_expression of NOS1 1 444 0.78 218.08 114.85
3 INT170025 Gene_expression of Fig4 1 588 0.67 183.27 113.32
4 INT65731 Gene_expression of Cnr1 1 234 0.78 63.82 109.34
5 INT90091 Gene_expression of GOPC 2 967 0.67 366.22 103.6
6 INT56130 Gene_expression of MC1R 1 259 0.78 62.7 97.55
7 INT56291 Gene_expression of Ros1 1 503 0.63 274.12 81.5
8 INT3214 Localization of Ins1 2 527 0.80 196.9 79.26
9 INT920 Localization of PLOD1 1 223 0.81 42.25 78.7
10 INT749 Gene_expression of HLA-B 1 341 0.75 224.12 77.37
11 INT171145 Positive_regulation of Fig4 2 274 0.59 93.55 69.81
12 INT65733 Positive_regulation of Cnr1 1 125 0.70 40.27 67.33
13 INT11937 Localization of Il6 1 228 0.81 139.83 64.39
14 INT21737 Binding of MC1R 2 129 0.48 45.45 56.54
15 INT62630 Positive_regulation of CNR1 1 86 0.70 40.34 51.51
16 INT30170 Gene_expression of Car2 1 330 0.66 77.26 46.76
17 INT17561 Localization of Car2 1 303 0.79 60.95 44.52
18 INT3933 Positive_regulation of PLOD1 1 128 0.70 30.76 42.03
19 INT30817 Gene_expression of Th 8 142 0.76 33.56 38.12
20 INT11325 Gene_expression of HLA-E 5 209 0.76 98.05 33.72
21 INT3913 Positive_regulation of ABAT 1 47 0.69 22.73 33.4
22 INT169180 Binding of SNRNP70 1 204 0.47 119.1 29.3
23 INT62169 Positive_regulation of MC1R 1 72 0.69 14.56 27.52
24 INT133876 Positive_regulation of Gene_expression of Ros1 1 141 0.32 75.55 27.45
25 INT145426 Positive_regulation of Ros1 2 185 0.56 106.76 27.21
26 INT36428 Binding of Chdh 13 42 0.47 48.04 26.54
27 INT2614 Gene_expression of CGA 1 187 0.78 105.89 24.77
28 INT12484 Binding of Drd2 2 45 0.48 15.17 24.72
29 INT48766 Regulation of NOS1 1 73 0.61 37.01 24.59
30 INT6441 Positive_regulation of CRH 1 98 0.69 57.22 24.12
31 INT18323 Negative_regulation of Localization of Ins1 1 122 0.58 45.74 23.04
32 INT23564 Negative_regulation of Car2 3 103 0.50 27.28 21.86
33 INT101537 Gene_expression of Vta1 2 19 0.50 1.88 20.76
34 INT79349 Gene_expression of Sert1 1 58 0.77 12.7 20.65
35 INT58477 Gene_expression of Chdh 2 33 0.74 39.48 19.78
36 INT12243 Positive_regulation of PRSS1 1 91 0.70 52.87 19.48
37 INT84712 Regulation of MC1R 1 36 0.62 9.34 16.91
38 INT197375 Gene_expression of Car1 1 84 0.65 16.46 16.45
39 INT22909 Positive_regulation of Chdh 4 26 0.68 28.69 16.13
40 INT36554 Gene_expression of PRSS1 1 70 0.78 50.25 15.33
41 INT29086 Negative_regulation of Sert1 1 37 0.58 7.49 14.98
42 INT3002 Binding of SUGT1 5 62 0.24 55.9 14.91
43 INT11699 Binding of HLA-E 8 85 0.47 52.51 13.41
44 INT54763 Binding of Il6 3 82 0.48 63.27 12.89
45 INT174844 Binding of Fig4 1 81 0.41 18.03 12.87
46 INT122812 Gene_expression of SNRNP70 3 130 0.75 67 12.5
47 INT9832 Gene_expression of Shbg 1 96 0.75 56.71 12.19
48 INT23402 Binding of HLA-DOA 1 74 0.48 52.01 10.89
49 INT89184 Gene_expression of Mc4r 1 55 0.77 23.85 10.65
50 INT73223 Gene_expression of UPF1 1 78 0.41 31.44 9.94
51 INT47744 Binding of Slc6a4 1 21 0.48 5.52 9.45
52 INT1224 Gene_expression of Fabp6 1 34 0.64 23.69 9.08
53 INT69264 Gene_expression of KIT 1 207 0.78 179.41 8.95
54 INT66646 Regulation of Chdh 3 13 0.44 16.24 8.84
55 INT89677 Gene_expression of PRKG1 1 38 0.78 13.98 8.56
56 INT18185 Gene_expression of Tyr 1 32 0.76 12.52 8.17
57 INT87699 Positive_regulation of WAS 1 16 0.45 5.84 8.03
58 INT32579 Binding of C4B 1 14 0.36 14.99 7.79
59 INT32580 Gene_expression of C4B 1 24 0.75 17.95 7.75
60 INT55185 Binding of Sert1 4 26 0.48 4.43 7.57
61 INT88587 Positive_regulation of Chrna6 1 10 0.46 3 7.35
62 INT6596 Positive_regulation of HLA-DRB1 1 33 0.61 27.01 7.26
63 INT157430 Gene_expression of Ephb6 1 18 0.70 8.13 7.14
64 INT31582 Gene_expression of Hdl1 2 103 0.66 118.95 6.42
65 INT79348 Positive_regulation of Sert1 3 11 0.64 4.32 6.17
66 INT112530 Localization of Ptgs2 1 13 0.70 7.77 5.86
67 INT52695 Regulation of Ptgs2 1 20 0.42 8.72 5.71
68 INT23401 Gene_expression of HLA-DOA 1 91 0.30 38.21 5.52
69 INT167600 Gene_expression of Chrm5 8 15 0.72 2.4 5.48
70 INT84909 Positive_regulation of SUGT1 2 22 0.08 22.01 5.43
71 INT125066 Negative_regulation of HDAC4 1 56 0.49 41.55 5.42
72 INT79346 Regulation of Sert1 1 10 0.58 2.36 5.18
73 INT44608 Gene_expression of C2 1 45 0.75 15.84 5.05
74 INT84911 Gene_expression of SUGT1 1 43 0.11 19.85 4.54
75 INT22145 Binding of Sugt1 2 16 0.13 8.31 4.37
76 INT173926 Positive_regulation of Atp6v1e1 1 21 0.27 11.39 4.24
77 INT156137 Gene_expression of Col1a2 1 28 0.73 13.3 3.99
78 INT59674 Gene_expression of Chrna6 1 8 0.47 2.12 3.94
79 INT174195 Negative_regulation of HLA-E 4 31 0.42 11.98 3.88
80 INT89678 Positive_regulation of Gene_expression of PRKG1 1 15 0.70 5.99 3.84
81 INT170553 Negative_regulation of Narf 11 12 0.05 16.19 3.78
82 INT45818 Gene_expression of C4A 1 35 0.75 26.4 3.52
83 INT59447 Negative_regulation of Tyr 3 12 0.56 4.57 3.32
84 INT102901 Regulation of Gene_expression of Th 2 12 0.60 2.42 3.22
85 INT12241 Negative_regulation of Positive_regulation of PRSS1 1 6 0.43 5.39 3.22
86 INT164087 Gene_expression of TPI1 2 42 0.78 5.39 3.21
87 INT109095 Binding of Drd4 1 7 0.40 3.6 3.18
88 INT212822 Negative_regulation of Chrm5 4 5 0.42 0.86 2.96
89 INT5913 Binding of OPA1 1 12 0.41 9.33 2.92
90 INT170557 Gene_expression of Lepr 2 16 0.67 17.26 2.78
91 INT160633 Gene_expression of Vdr 2 21 0.77 10.01 2.73
92 INT176531 Gene_expression of SHC1 1 3 0.67 9.5 2.62
93 INT1540 Positive_regulation of SAFB 1 9 0.43 1.97 2.56
94 INT18969 Gene_expression of HLA-DQA1 1 29 0.65 12.19 2.54
95 INT136681 Gene_expression of Shc1 4 13 0.77 9.67 2.52
96 INT184914 Negative_regulation of Gene_expression of Th 1 15 0.43 9.17 2.46
97 INT211970 Negative_regulation of Best1 2 49 0.14 37.33 2.32
98 INT212819 Regulation of Chrm5 3 2 0.44 1.64 2.22
99 INT34644 Binding of HLA-C 2 19 0.47 9.41 2.2
100 INT126513 Gene_expression of Col1a1 1 23 0.75 10.92 2.18
101 INT170548 Regulation of Narf 24 1 0.06 34.17 2.18
102 INT103298 Binding of CALCR 5 5 0.47 6.03 2.15
103 INT125108 Binding of Chrna7 1 4 0.47 0.8 2.03
104 INT170556 Gene_expression of Narf 12 1 0.06 17.85 1.96
105 INT116848 Negative_regulation of Chdh 2 10 0.42 19.68 1.95
106 INT122534 Binding of Shc1 1 6 0.48 3.59 1.94
107 INT309185 Gene_expression of Rbms1 1 16 0.24 0.87 1.93
108 INT148702 Positive_regulation of UPF1 2 29 0.31 12.9 1.91
109 INT207035 Gene_expression of CFB 1 4 0.63 18.4 1.72
110 INT178841 Localization of SNRNP70 2 27 0.78 10.35 1.71
111 INT108252 Positive_regulation of Renbp 1 16 0.24 11.66 1.68
112 INT146943 Gene_expression of Src 1 13 0.49 6.65 1.65
113 INT170547 Positive_regulation of Narf 28 29 0.06 64.48 1.61
114 INT102428 Binding of C2 1 17 0.32 5.12 1.58
115 INT23191 Gene_expression of HDLCQ1 1 13 0.60 14.39 1.58
116 INT136680 Negative_regulation of Gene_expression of Shc1 1 4 0.43 3.36 1.57
117 INT9466 Binding of APOB 1 27 0.41 19.36 1.56
118 INT139317 Negative_regulation of Col1a2 1 8 0.41 7.17 1.54
119 INT650 Gene_expression of Afp 1 13 0.78 7.44 1.47
120 INT142719 Binding of Col1a1 3 7 0.34 5.83 1.47
121 INT131767 Positive_regulation of CHRNA7 1 4 0.31 0.87 1.47
122 INT130260 Gene_expression of Nfkb2 1 7 0.60 3.85 1.43
123 INT65153 Binding of HLA-DPB1 1 5 0.34 3.29 1.4
124 INT212821 Positive_regulation of Sugt1 2 5 0.02 1.25 1.34
125 INT24000 Regulation of Sp1 2 2 0.22 1.25 1.27
126 INT128176 Regulation of RHOA 1 13 0.44 4.35 1.26
127 INT170550 Binding of Narf 8 9 0.04 14.89 1.18
128 INT50146 Gene_expression of Dcn 9 18 0.51 0.9 1.17
129 INT212818 Binding of Chrm5 3 5 0.35 1.34 1.15
130 INT105865 Regulation of Gene_expression of PRKG1 1 4 0.12 1.82 1.15
131 INT58042 Binding of HLA-DQA1 1 8 0.24 5.03 1.14
132 INT189287 Binding of Atp6v1e1 3 7 0.19 6.9 1.14
133 INT108246 Regulation of Renbp 3 5 0.21 4.66 1.12
134 INT143208 Negative_regulation of TPI1 9 30 0.59 7.54 1.08
135 INT125147 Binding of Mc4r 1 10 0.41 3.55 1.08
136 INT172616 Regulation of HNF4A 1 9 0.06 4.25 1.02
137 INT129425 Negative_regulation of Ldlr 1 22 0.42 17.15 0.97
138 INT197365 Localization of Car1 1 7 0.73 1.11 0.94
139 INT39415 Gene_expression of HBN1 1 33 0.43 19.31 0.93
140 INT212820 Transcription of Chrm5 2 1 0.68 0.36 0.91
141 INT134654 Localization of CALCR 2 5 0.39 3.21 0.85
142 INT212817 Regulation of Regulation of Chrm5 1 1 0.44 0.13 0.81
143 INT192156 Negative_regulation of Col1a1 1 6 0.39 3.92 0.8
144 INT27135 Gene_expression of SAFB 1 9 0.68 0.96 0.79
145 INT72380 Positive_regulation of Shc1 5 10 0.69 6.87 0.77
146 INT39820 Gene_expression of CALCR 1 16 0.37 4.96 0.74
147 INT170546 Gene_expression of Renbp 4 15 0.32 14.33 0.72
148 INT187506 Binding of Cebpg 2 7 0.47 2.27 0.72
149 INT311611 Regulation of Klhl25 1 1 0.11 0.63 0.72
150 INT262107 Binding of Vdr 7 9 0.48 6.56 0.71
151 INT164088 Positive_regulation of TPI1 2 8 0.50 1.26 0.7
152 INT262060 Positive_regulation of Vdr 1 8 0.58 2.84 0.67
153 INT276199 Binding of Pten 1 2 0.30 0.4 0.67
154 INT165813 Gene_expression of CES1 1 31 0.76 6.08 0.66
155 INT191347 Regulation of Shc1 4 6 0.27 3.6 0.6
156 INT212816 Positive_regulation of Chrm5 1 1 0.46 0.19 0.6
157 INT142184 Regulation of TXK 1 10 0.11 8.25 0.59
158 INT64953 Negative_regulation of HLA-DRB1 1 9 0.58 5.15 0.56
159 INT191350 Gene_expression of POLDIP3 1 5 0.15 2.22 0.51
160 INT136679 Negative_regulation of Shc1 1 3 0.59 2.5 0.51
161 INT142835 Regulation of Localization of Ptgs2 1 2 0.25 0.26 0.5
162 INT72379 Localization of Shc1 2 4 0.74 0.89 0.49
163 INT170554 Binding of Renbp 1 17 0.17 12.36 0.45
164 INT50135 Positive_regulation of Dcn 1 5 0.45 0.7 0.44
165 INT206913 Localization of Atp6v1e1 1 8 0.32 3.55 0.43
166 INT170549 Localization of Narf 2 1 0.07 2.67 0.38
167 INT170555 Gene_expression of Myoc 2 1 0.66 2.17 0.37
168 INT196258 Binding of FUT2 2 5 0.32 1.83 0.34
169 INT130739 Binding of Col1a2 2 2 0.35 2.38 0.34
170 INT211971 Binding of Best1 1 16 0.22 7.73 0.33
171 INT262063 Localization of Vdr 3 3 0.75 1.76 0.33
172 INT178326 Gene_expression of Pon1 3 1 0.67 2.93 0.28
173 INT311615 Binding of CHRNB1 1 1 0.01 0.24 0.28
174 INT178329 Negative_regulation of Gene_expression of Pon1 1 1 0.43 0.93 0.28
175 INT219843 Gene_expression of SULT2B1 4 9 0.62 0.92 0.27
176 INT297804 Regulation of Lrp5 1 6 0.60 2.31 0.27
177 INT41804 Localization of Afp 2 3 0.81 0.28 0.27
178 INT66978 Binding of Pon1 6 2 0.48 6.13 0.27
179 INT254427 Binding of Lrp5 3 10 0.48 5.43 0.26
180 INT190400 Gene_expression of FUT2 9 12 0.09 2.48 0.22
181 INT178328 Positive_regulation of Pon1 1 2 0.50 2.2 0.22
182 INT50137 Regulation of Gene_expression of Dcn 1 2 0.26 0.09 0.21
183 INT171597 Gene_expression of APOC3 6 9 0.77 3.18 0.2
184 INT170886 Gene_expression of AIRE 1 2 0.49 4.63 0.19
185 INT254429 Negative_regulation of Lrp5 1 4 0.57 1.95 0.18
186 INT213752 Positive_regulation of FUT2 3 4 0.03 0.47 0.17
187 INT207020 Binding of CDH13 1 1 0.35 0.51 0.16
188 INT171595 Negative_regulation of APOC3 2 3 0.43 1.99 0.15
189 INT171589 Transcription of APOC3 1 2 0.71 1.25 0.15
190 INT185467 Gene_expression of Abcg5 1 2 0.64 0.86 0.15
191 INT174342 Binding of C4A 1 6 0.34 4.6 0.14
192 INT185466 Regulation of Gene_expression of Abcg5 1 1 0.43 0 0.13
193 INT185463 Positive_regulation of Abcg5 1 1 0.48 0 0.13
194 INT70262 Gene_expression of Pth 2 8 0.66 5.64 0.12
195 INT188139 Positive_regulation of FST 1 9 0.67 0.06 0.11
196 INT155701 Gene_expression of FST 1 5 0.75 0.34 0.11
197 INT191353 Localization of SHC1 1 2 0.73 0.75 0.1
198 INT195479 Binding of Dcn 2 3 0.19 0.05 0.08
199 INT178330 Regulation of Pon1 3 1 0.62 2.39 0.08
200 INT11598 Positive_regulation of HDLCQ1 1 6 0.45 3.6 0.07
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