J:BMC Infect Dis

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT179502 Binding of Cd14 and Tlr4 29 5 0.39 13.77 5.73
2 INT333499 Binding of IGHE and PHB2 1 3 0.14 4.08 0.95
3 INT248271 IL6 Regulation of Gene_expression of Crp 3 1 0.27 1.7 0.73
4 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 2 0.13 4.58 0.48
5 INT179432 Binding of pcp and AICDA 1 3 0.03 3.51 0.43
6 INT297423 Gene_expression of Il4 Regulation of Ppara 1 1 0.07 1.19 0.38
7 INT297424 Gene_expression of Stat6 Regulation of Ppara 1 1 0.17 1.19 0.38
8 INT297425 Il4 Regulation of Ppara 1 1 0.07 1.17 0.38
9 INT297426 Stat6 Regulation of Ppara 1 1 0.17 1.19 0.38
10 INT297428 Lvs Positive_regulation of Gene_expression of Il13 1 1 0.06 1.2 0.3
11 INT297422 Lvs Positive_regulation of Gene_expression of Il4 1 1 0.04 1.2 0.3
12 INT297427 Flg Positive_regulation of Gene_expression of Il13 1 1 0.11 1.2 0.3
13 INT315369 Binding of IL6 and Crp 1 2 0.10 2.09 0.3
14 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 1 0.03 0.63 0.28
15 INT188746 Binding of CSF2 and HIVEP1 1 3 0.04 3.99 0.21
16 INT325529 Binding of Stat3 and Ep300 1 1 0.01 0.22 0.19
17 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 1 0.02 0.22 0.19
18 INT353298 IFNA1 Positive_regulation of CD8A 1 2 0.04 0.75 0.19
19 INT189795 Tlr4 Positive_regulation of Cd14 1 1 0.12 0.77 0.19
20 INT190381 IL1A Regulation of Transcription of DEFB4A 1 2 0.06 0.93 0.18
21 INT325532 Binding of Cx3cl1 and Cxcl10 1 1 0.28 0.67 0.16
22 INT246365 CALM1 Regulation of MAP2K6 1 1 0.00 0.34 0.15
23 INT232592 Binding of Csf2 and Gtf3a 1 1 0.02 0.47 0.14
24 INT189796 Binding of EHHADH and Cd14 1 2 0.13 0.9 0.14
25 INT324128 Binding of Cd4 and Cd40 2 1 0.29 0.3 0.13
26 INT237442 Ass1 Positive_regulation of S100b 1 1 0.00 0.18 0.13
27 INT246364 GOPC Regulation of SETBP1 1 1 0.02 0.98 0.13
28 INT174820 IL6 Positive_regulation of VEGFA 1 2 0.20 3.32 0.12
29 INT174821 VEGFA Positive_regulation of Gene_expression of IL6 1 2 0.20 3.13 0.12
30 INT190382 IL1A Regulation of Regulation of DEFB4A 1 1 0.06 0.57 0.1
31 INT351426 SEPT5 Regulation of HRAS 1 1 0.00 0.7 0.09
32 INT351425 HRAS Regulation of SEPT5 1 1 0.00 0.7 0.09
33 INT188748 AGRP Negative_regulation of CSF2 1 1 0.05 1.26 0.08
34 INT188745 AGRP Regulation of Gene_expression of CSF2 1 2 0.07 1.48 0.08
35 INT337572 TREM1 Regulation of CRP 1 1 0.05 0.99 0.07
36 INT246363 SETBP1 Regulation of GBP2 1 2 0.02 0.4 0.06
37 INT220724 Binding of IGFALS and SOD1 1 2 0.06 2.1 0.06
38 INT232590 Csf2 Positive_regulation of Serpina5 1 1 0.17 0.65 0.05
39 INT191590 Binding of AMBP and Arsb 1 1 0.00 1.82 0.04
40 INT228925 Binding of IFN1@ and IFNG 1 1 0.24 2.06 0.03
41 INT228229 Binding of Cd4 and Ntm 1 1 0.02 1.03 0.03
42 INT220725 Binding of IGFALS and IGHD1OR15-1A 1 1 0.01 1.05 0.03
43 INT232591 Binding of Csf2 and Wbc1 1 1 0.06 0.47 0.03
44 INT180164 Gast Positive_regulation of Nfasc 1 1 0.02 1.31 0
45 INT194244 Binding of SFSWAP and IgG 1 1 0.05 0.46 0
46 INT194226 Binding of IGHG3 and SFSWAP 1 2 0.03 0.93 0
47 INT237110 Binding of CAPN7 and Iac 1 3 0.08 0 0
48 INT348334 Gml Positive_regulation of Micrl 1 1 0.01 0.51 0
49 INT191577 Binding of Pde6b and Tst 1 1 0.02 0.48 0
50 INT188747 AGRP Positive_regulation of Gene_expression of CSF2 1 1 0.06 1.28 0
51 INT188744 AGRP Regulation of CSF2 1 1 0.05 1.04 0
52 INT188749 Binding of HIVEP1 and ADC 1 1 0.02 0.92 0
53 INT194243 Binding of SFSWAP and Ighg1 1 1 0.01 0.46 0
54 INT237095 Binding of HMI and CAPN7 1 1 0.05 0.55 0
55 INT188750 Binding of CD4 and ADC 1 1 0.16 0.93 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 9 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 17 1575 0.78 1135.66 424.22
3 INT5059 Positive_regulation of TNF 2 1050 0.70 896.51 322.81
4 INT10832 Gene_expression of IL8 1 1050 0.78 698.72 270
5 INT9659 Gene_expression of Il6 2 991 0.78 715.11 265.57
6 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
7 INT16868 Gene_expression of Il6 16 807 0.78 499.48 256.57
8 INT6482 Positive_regulation of Gene_expression of TNF 3 659 0.70 569.88 210
9 INT11313 Positive_regulation of Il6 3 526 0.70 331.27 201.59
10 INT6488 Gene_expression of Tnf 4 484 0.78 339.61 191.58
11 INT10194 Positive_regulation of IL6 8 702 0.70 600.62 183.38
12 INT19472 Gene_expression of Il1 1 554 0.76 419.75 175.35
13 INT15516 Gene_expression of Crp 24 711 0.77 615.33 173.09
14 INT867 Gene_expression of IFNA1 6 930 0.78 594.85 168.03
15 INT55879 Gene_expression of CCL2 2 421 0.78 240.74 166.02
16 INT15515 Positive_regulation of Crp 7 700 0.70 604.24 150.15
17 INT9852 Positive_regulation of Gpt 1 563 0.70 364.64 146.82
18 INT5116 Gene_expression of IL2 2 670 0.78 291.13 146.69
19 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
20 INT48895 Gene_expression of Il10 1 333 0.78 221.2 138.52
21 INT115386 Gene_expression of Ppara 6 779 0.77 549.99 128.36
22 INT7533 Gene_expression of Tlr4 8 720 0.78 343.22 121.57
23 INT17612 Gene_expression of CRP 8 676 0.78 580.61 119.03
24 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
25 INT48593 Positive_regulation of NOS1 2 420 0.68 226.15 114.71
26 INT20374 Gene_expression of Il4 12 515 0.76 306.15 114.12
27 INT90 Localization of Gast 1 400 0.81 137.67 113
28 INT11051 Positive_regulation of Gene_expression of IL6 3 415 0.69 319.21 109.3
29 INT27096 Positive_regulation of Nfkb1 1 325 0.70 195.11 109.06
30 INT60526 Gene_expression of IL10 1 449 0.78 292.71 107.84
31 INT12082 Localization of IL6 2 365 0.81 241.78 105.78
32 INT18009 Positive_regulation of CRP 8 518 0.70 553.03 103.74
33 INT90091 Gene_expression of GOPC 1 967 0.67 366.22 103.6
34 INT11587 Gene_expression of CSF2 47 645 0.78 544.38 93.89
35 INT1160 Positive_regulation of Rbm39 1 122 0.57 28.19 90.28
36 INT71789 Positive_regulation of MAPK1 1 396 0.70 234.44 89.27
37 INT48408 Gene_expression of ICAM1 2 494 0.78 340.08 88.6
38 INT84546 Positive_regulation of Ppara 1 481 0.70 334.21 83.45
39 INT68682 Positive_regulation of VEGFA 1 640 0.70 454.14 81.65
40 INT60691 Gene_expression of Il12a 1 331 0.78 208.03 75.96
41 INT5056 Gene_expression of IFNG 1 216 0.78 137.52 74.57
42 INT48244 Gene_expression of Il4 1 172 0.76 132.38 73.42
43 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
44 INT56298 Gene_expression of IL4 1 306 0.78 182.18 72.92
45 INT12720 Positive_regulation of Il1 4 246 0.70 195.97 72.05
46 INT5969 Gene_expression of Il1a 1 221 0.75 96.31 71.38
47 INT170332 Gene_expression of IFN1@ 21 477 0.75 275.21 69.65
48 INT6489 Positive_regulation of Gene_expression of Tnf 2 140 0.70 92.31 67.85
49 INT19511 Localization of Il6 3 212 0.81 118.17 67.67
50 INT6486 Positive_regulation of Tnf 1 168 0.70 123.47 66.05
51 INT4960 Positive_regulation of CSF2 12 285 0.70 256.73 65.73
52 INT3375 Gene_expression of IGHE 5 535 0.77 387.47 65.46
53 INT11807 Gene_expression of Il2 2 266 0.78 112 64.97
54 INT15514 Negative_regulation of Crp 1 275 0.59 194.6 64.86
55 INT11937 Localization of Il6 1 228 0.81 139.83 64.39
56 INT822 Gene_expression of ESR1 2 529 0.78 302.16 63.64
57 INT9657 Positive_regulation of Gene_expression of Il6 1 237 0.70 180.45 63.6
58 INT1951 Positive_regulation of Tlr4 4 345 0.70 176.99 62.42
59 INT10706 Regulation of Il6 2 150 0.62 93.23 62.34
60 INT67981 Positive_regulation of CCL2 1 165 0.70 136.84 61.85
61 INT5058 Positive_regulation of IFNA1 5 356 0.70 245.75 60.52
62 INT14740 Gene_expression of TGFB1 1 272 0.78 168.48 60.18
63 INT546 Binding of ALB 1 311 0.48 85.98 60.14
64 INT55344 Gene_expression of Ros1 1 396 0.54 217.64 59.98
65 INT6477 Gene_expression of IL1RN 1 213 0.77 114.69 58.62
66 INT46637 Gene_expression of CXCL10 1 172 0.78 121.94 57.74
67 INT9408 Positive_regulation of Crp 3 296 0.69 242.27 57.35
68 INT48891 Positive_regulation of Il10 1 143 0.70 101.42 56.72
69 INT4509 Gene_expression of IGG 4 426 0.76 293.69 56.64
70 INT78899 Gene_expression of CCL5 2 155 0.77 84.02 55.09
71 INT251 Regulation of INS 3 398 0.62 232.47 55.04
72 INT117223 Gene_expression of TLR4 1 348 0.78 206.18 54.42
73 INT1027 Gene_expression of Lbp 18 132 0.77 106.7 54.16
74 INT12345 Gene_expression of Il2 1 142 0.78 59.17 51.21
75 INT19775 Localization of Il1 2 183 0.78 145.5 50.91
76 INT9210 Regulation of IL6 3 166 0.62 125.61 49.95
77 INT22454 Regulation of Crp 7 213 0.62 160.67 49.24
78 INT17881 Gene_expression of LEP 1 278 0.78 221.61 48.31
79 INT1028 Positive_regulation of Lbp 3 102 0.69 67.86 46.05
80 INT145266 Gene_expression of IL17A 2 154 0.75 109.83 45.33
81 INT16364 Gene_expression of HLA-DRA 2 234 0.78 118.81 45.01
82 INT16364 Gene_expression of HLA-DRA 3 234 0.78 118.81 45.01
83 INT6979 Positive_regulation of CA2 2 206 0.67 50.79 44.97
84 INT18522 Positive_regulation of Gene_expression of IFNA1 1 248 0.67 160.85 44.87
85 INT3361 Positive_regulation of Esr1 1 273 0.69 208.53 44.81
86 INT2774 Binding of Crp 8 241 0.48 195.89 44.39
87 INT4216 Gene_expression of CD40LG 6 328 0.78 256.02 44.23
88 INT100939 Gene_expression of Il13 4 176 0.73 125.1 43.38
89 INT613 Gene_expression of Alb 1 268 0.78 149.84 42.78
90 INT157666 Positive_regulation of GOPC 1 335 0.60 120.19 42.75
91 INT4004 Gene_expression of IGHG3 13 321 0.71 221.03 42.33
92 INT89 Positive_regulation of Gast 2 187 0.70 80.49 42.07
93 INT13556 Gene_expression of CD4 16 367 0.78 230.82 41.74
94 INT30 Gene_expression of Gast 2 158 0.78 99 41.45
95 INT97596 Localization of S100a8 2 94 0.78 90.69 40.41
96 INT52732 Negative_regulation of CRP 1 169 0.59 138.47 40.33
97 INT173693 Localization of Gopc 2 249 0.65 70.49 38.81
98 INT3758 Gene_expression of ALB 11 326 0.78 184.65 38.75
99 INT9094 Gene_expression of COL7A1 1 277 0.77 143.42 38.73
100 INT11439 Positive_regulation of Csf2 1 105 0.69 62.63 37.77
101 INT104551 Gene_expression of Il18 2 156 0.76 115.51 36.95
102 INT9082 Positive_regulation of ESR1 6 238 0.69 148.51 36.69
103 INT9239 Regulation of Gene_expression of IL6 1 106 0.61 75.24 36.53
104 INT133028 Gene_expression of TLR2 2 209 0.73 131.92 36.17
105 INT59466 Gene_expression of ISYNA1 20 204 0.77 112.57 35.48
106 INT79060 Gene_expression of NOS2 1 116 0.78 69.25 34.84
107 INT17381 Gene_expression of Tbxa2r 1 146 0.78 65.01 34.15
108 INT16960 Gene_expression of Crp 3 166 0.76 116.21 34.07
109 INT49214 Gene_expression of Cd4 2 269 0.78 154.22 34.05
110 INT49214 Gene_expression of Cd4 1 269 0.78 154.22 34.05
111 INT77310 Gene_expression of Aif1 1 89 0.78 50.49 33.68
112 INT9694 Positive_regulation of Csf2 1 102 0.68 70.09 33.07
113 INT6302 Binding of IFNA1 1 196 0.48 133.85 32.73
114 INT62830 Gene_expression of VCAM1 1 149 0.78 125.23 32.4
115 INT73498 Gene_expression of IL13 1 117 0.44 83.85 32.26
116 INT22939 Gene_expression of Csf2 1 164 0.78 85.1 32.22
117 INT13186 Positive_regulation of Il4 1 113 0.68 71.22 31.4
118 INT56809 Binding of Tlr4 9 184 0.48 106.02 31.18
119 INT56290 Negative_regulation of Gene_expression of Il6 1 79 0.59 47.98 31.07
120 INT54302 Positive_regulation of Gene_expression of Il4 7 126 0.68 86.18 30.75
121 INT34729 Positive_regulation of IFN1@ 2 233 0.67 128.04 30.38
122 INT11554 Negative_regulation of CSF2 10 129 0.59 108.55 29.44
123 INT91 Positive_regulation of Localization of Gast 1 96 0.70 23.22 29.36
124 INT86437 Binding of IL6 12 154 0.48 121.22 29.3
125 INT15610 Localization of GOPC 1 223 0.65 68.26 28.7
126 INT122039 Positive_regulation of Gene_expression of Ppara 1 144 0.68 113.55 28.55
127 INT66200 Gene_expression of Gfap 12 215 0.78 88.04 28.25
128 INT11361 Gene_expression of SERPINE1 1 183 0.78 136.45 27.97
129 INT83708 Negative_regulation of MAPK1 1 156 0.57 84.93 27.85
130 INT14690 Localization of CSF2 4 124 0.80 85.17 27.26
131 INT69157 Gene_expression of IL5 1 127 0.77 102.58 26.81
132 INT3760 Positive_regulation of ALB 1 142 0.70 87.46 26.7
133 INT100861 Binding of CRP 1 179 0.48 175.2 26.45
134 INT19856 Gene_expression of CD8A 6 240 0.75 147.86 26.39
135 INT20462 Binding of ESR1 1 210 0.44 102.7 26.34
136 INT53015 Gene_expression of TP53INP2 1 50 0.78 9.05 26.23
137 INT76095 Positive_regulation of ISYNA1 16 117 0.55 79.73 25.86
138 INT130186 Gene_expression of Ccl5 1 101 0.74 79.96 25.01
139 INT1030 Localization of Lbp 1 52 0.74 38.92 24.91
140 INT58192 Positive_regulation of MRI1 4 86 0.61 53.81 24.68
141 INT9355 Binding of pcp 2 81 0.46 10.41 24.22
142 INT55583 Localization of IFNA1 1 135 0.78 85.07 24.13
143 INT147792 Gene_expression of COPD 1 230 0.70 287.13 24.1
144 INT17275 Gene_expression of HIVEP1 23 267 0.75 232.07 24.06
145 INT4781 Gene_expression of TH 1 68 0.73 26.92 24.01
146 INT25607 Binding of Il1 1 82 0.47 64.4 23.9
147 INT58288 Positive_regulation of Gene_expression of Crp 1 83 0.61 82.23 23.7
148 INT8775 Binding of IGHE 1 167 0.48 102.61 23.54
149 INT11746 Positive_regulation of Il1a 1 65 0.63 42.94 23.54
150 INT94335 Positive_regulation of CXCL10 1 71 0.58 50.69 23
151 INT69322 Negative_regulation of MAPK14 1 70 0.54 42.92 22.71
152 INT11659 Gene_expression of COL2A1 2 164 0.78 78.49 22.58
153 INT8640 Positive_regulation of HSD11B1 1 332 0.67 377.84 22.36
154 INT48312 Gene_expression of NTRK1 1 72 0.78 38.21 22.24
155 INT5905 Negative_regulation of ELANE 1 113 0.59 47.43 22.09
156 INT84732 Positive_regulation of Hand2 2 81 0.69 62.07 22
157 INT23257 Regulation of CRP 2 127 0.62 100.05 21.87
158 INT8580 Gene_expression of ELANE 1 132 0.75 62.98 21.79
159 INT78057 Localization of Tlr4 3 140 0.77 67.75 21.72
160 INT96156 Gene_expression of Cd40 10 144 0.77 56.95 21.7
161 INT7535 Negative_regulation of Tlr4 1 111 0.56 56.84 21.37
162 INT5328 Positive_regulation of CD4 3 191 0.69 133.43 21.31
163 INT614 Gene_expression of Cxcl2 1 29 0.76 25.53 20.8
164 INT28216 Gene_expression of HRAS 2 173 0.75 93.97 20.78
165 INT109650 Gene_expression of Aqp4 1 87 0.78 51.52 20.72
166 INT5096 Positive_regulation of Gtf3a 2 79 0.60 42.26 20.62
167 INT63340 Positive_regulation of Gene_expression of ICAM1 1 109 0.70 90.82 20.61
168 INT78901 Localization of CCL5 1 67 0.78 40.79 20.59
169 INT51474 Binding of Il6 1 55 0.48 44.99 20.52
170 INT62042 Positive_regulation of Gene_expression of IL4 1 67 0.56 42.05 20.39
171 INT12265 Positive_regulation of IgG 1 168 0.63 104.89 19.76
172 INT18311 Positive_regulation of CD8A 1 145 0.69 113.48 19.44
173 INT712 Positive_regulation of LDHA 9 160 0.70 175.25 19.11
174 INT70614 Gene_expression of FAS 2 118 0.75 112.33 19.01
175 INT14737 Gene_expression of FN1 1 117 0.78 78.74 18.99
176 INT192409 Positive_regulation of Gene_expression of IFN1@ 3 102 0.67 64.66 18.8
177 INT18010 Positive_regulation of CD40LG 4 122 0.70 100.8 18.46
178 INT4420 Positive_regulation of GOT1 1 103 0.64 88.4 18.38
179 INT3952 Negative_regulation of ALB 3 116 0.59 72.18 18.35
180 INT52179 Regulation of Lbp 1 39 0.61 25.4 18.32
181 INT11938 Positive_regulation of Localization of Il6 1 61 0.70 35.72 18.25
182 INT23635 Positive_regulation of MMP12 1 31 0.59 28.19 17.95
183 INT20631 Positive_regulation of CHKB 6 166 0.69 109.86 17.92
184 INT80755 Gene_expression of CD40 1 88 0.75 53.68 17.86
185 INT38056 Localization of Crp 4 71 0.78 53.14 17.03
186 INT12922 Gene_expression of Atp9a 2 115 0.75 50.95 17.01
187 INT10187 Gene_expression of Il2ra 3 91 0.78 52.67 16.66
188 INT22900 Positive_regulation of Cd4 2 126 0.67 82.77 16.43
189 INT20622 Gene_expression of LDHA 1 107 0.76 77.97 16.3
190 INT10721 Gene_expression of BDNF-AS 3 119 0.76 72.8 16.29
191 INT899 Gene_expression of F13A1 2 122 0.70 78.02 16.26
192 INT108588 Gene_expression of CASP3 4 126 0.78 84.49 16.2
193 INT12617 Regulation of ADCY1 2 41 0.61 7.38 15.94
194 INT9220 Gene_expression of Ighg1 2 125 0.77 85.74 15.92
195 INT11685 Regulation of CSF2 9 99 0.59 58.82 15.9
196 INT68913 Gene_expression of Cd14 3 55 0.76 38.99 15.67
197 INT170754 Localization of IFN1@ 1 121 0.78 66.78 15.6
198 INT43906 Regulation of Tlr4 4 71 0.53 35.18 15.49
199 INT171666 Regulation of GOPC 1 117 0.39 40.41 15.47
200 INT170855 Negative_regulation of GOPC 1 188 0.38 70.92 15.41
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