J:BMC Microbiol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT181455 Binding of Ccr5 and Ccl5 11 1 0.39 12.13 3.66
2 INT113550 Binding of FN1 and VTN 6 1 0.30 5.24 1.91
3 INT181450 Binding of Ccr5 and Ccl3 4 1 0.18 2.19 1.03
4 INT178663 Binding of CXCR3 and TH1L 2 1 0.04 2.24 1.01
5 INT163390 Il6 Positive_regulation of Gene_expression of Crp 2 1 0.03 3.42 0.95
6 INT244232 Binding of Ccr5 and Ccl4 3 1 0.17 1.48 0.55
7 INT114754 Il6 Positive_regulation of Gene_expression of Crp 2 1 0.08 1.67 0.47
8 INT178664 Binding of CCR5 and TH1L 1 1 0.04 1.04 0.44
9 INT178662 IFN1@ Positive_regulation of CXCL9 1 1 0.20 0.5 0.36
10 INT246439 Hand1 Positive_regulation of Gene_expression of Cd79a 1 1 0.04 0.78 0.27
11 INT246442 Hand2 Positive_regulation of Gene_expression of Cd79a 1 1 0.03 0.78 0.27
12 INT246435 Xcl1 Positive_regulation of Gene_expression of Cd79a 1 1 0.07 0.83 0.27
13 INT246438 Ccl5 Positive_regulation of Gene_expression of Cd79a 1 1 0.13 0.83 0.26
14 INT251492 Binding of HSPD1 and SOD1 1 2 0.02 1.45 0.18
15 INT246437 Ccl5 Positive_regulation of Regulation of Hand1 1 1 0.19 0.76 0.17
16 INT246440 Ccl5 Positive_regulation of Positive_regulation of Xcl1 1 1 0.27 1.28 0.16
17 INT328793 Binding of Mmp7 and Timp2 1 1 0.00 0.72 0.15
18 INT328794 Binding of Timp2 and Mmp3 1 1 0.00 0.72 0.15
19 INT221989 Cpn1 Positive_regulation of Localization of Ccl2 1 1 0.07 1.6 0.12
20 INT196699 Binding of Cog1 and Rbm39 1 1 0.00 1.85 0.09
21 INT246441 Ccl5 Positive_regulation of Gene_expression of Aif1 1 1 0.03 0.71 0.06
22 INT246436 Ccl5 Regulation of Aif1 1 1 0.01 0.67 0.06
23 INT355906 MAPK1 Positive_regulation of Localization of IL8 1 1 0.02 0.67 0.05
24 INT307704 Binding of Gsr and Rb(8.17)6Sic 1 1 0.01 1.49 0.03
25 INT221991 Cpn1 Regulation of Gene_expression of Crp 1 1 0.05 1.14 0.03
26 INT234357 GRHPR Regulation of MRT5 1 1 0.00 0.05 0
27 INT232715 Binding of LAMB2 and SAFB 1 1 0.00 0.29 0
28 INT232717 Binding of COL4A4 and SAFB 1 1 0.00 0.3 0
29 INT232716 Binding of FN1 and SAFB 1 1 0.00 0.3 0
30 INT171572 Binding of ALPP and IGHG3 1 1 0.01 0.41 0
31 INT232714 Binding of UBE2K and MMRN1 1 1 0.00 0.1 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT10832 Gene_expression of IL8 12 1050 0.78 698.72 270
2 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
3 INT15516 Gene_expression of Crp 5 711 0.77 615.33 173.09
4 INT867 Gene_expression of IFNA1 2 930 0.78 594.85 168.03
5 INT120811 Gene_expression of Gopc 3 1174 0.59 428.49 150.55
6 INT60694 Gene_expression of Il10 2 567 0.78 369.48 143.69
7 INT12339 Localization of IL8 35 437 0.81 251.87 117.39
8 INT48593 Positive_regulation of NOS1 3 420 0.68 226.15 114.71
9 INT20374 Gene_expression of Il4 1 515 0.76 306.15 114.12
10 INT27096 Positive_regulation of Nfkb1 1 325 0.70 195.11 109.06
11 INT90091 Gene_expression of GOPC 6 967 0.67 366.22 103.6
12 INT10838 Positive_regulation of IL8 6 381 0.70 295.51 101.62
13 INT11381 Positive_regulation of IL1B 1 330 0.70 209.31 100.9
14 INT71789 Positive_regulation of MAPK1 40 396 0.70 234.44 89.27
15 INT60691 Gene_expression of Il12a 2 331 0.78 208.03 75.96
16 INT56298 Gene_expression of IL4 1 306 0.78 182.18 72.92
17 INT10837 Positive_regulation of Gene_expression of IL8 10 294 0.70 190.08 70.34
18 INT170332 Gene_expression of IFN1@ 1 477 0.75 275.21 69.65
19 INT6849 Localization of IL1B 1 229 0.81 112.56 69.63
20 INT19511 Localization of Il6 2 212 0.81 118.17 67.67
21 INT1425 Gene_expression of Rbm39 6 143 0.58 51.32 65.44
22 INT11937 Localization of Il6 3 228 0.81 139.83 64.39
23 INT5058 Positive_regulation of IFNA1 3 356 0.70 245.75 60.52
24 INT4509 Gene_expression of IGG 1 426 0.76 293.69 56.64
25 INT5770 Binding of Rbm39 3 88 0.41 13.23 55.5
26 INT20375 Gene_expression of Hand1 3 213 0.60 148.51 54.53
27 INT52264 Gene_expression of IK 2 180 0.77 90.87 51.87
28 INT20382 Gene_expression of Hand2 1 211 0.66 142.26 51.05
29 INT6473 Positive_regulation of Gene_expression of IL1B 1 204 0.70 117.23 50.86
30 INT71786 Phosphorylation of MAPK1 11 256 0.82 110.09 46.17
31 INT2774 Binding of Crp 2 241 0.48 195.89 44.39
32 INT52531 Gene_expression of Nfkb1 2 153 0.75 82.84 42.9
33 INT157666 Positive_regulation of GOPC 2 335 0.60 120.19 42.75
34 INT11939 Negative_regulation of Il6 1 138 0.59 87.46 41.24
35 INT48222 Positive_regulation of Localization of IL8 19 123 0.59 78.04 37.2
36 INT80690 Positive_regulation of MAPK8 19 223 0.68 125.63 36.75
37 INT72651 Gene_expression of TH1L 2 114 0.75 80.15 35.15
38 INT1163 Negative_regulation of Rbm39 2 64 0.29 16.8 34.74
39 INT16960 Gene_expression of Crp 1 166 0.76 116.21 34.07
40 INT49214 Gene_expression of Cd4 1 269 0.78 154.22 34.05
41 INT13186 Positive_regulation of Il4 1 113 0.68 71.22 31.4
42 INT129207 Gene_expression of Cxcl1 1 114 0.75 68.54 30.82
43 INT34729 Positive_regulation of IFN1@ 2 233 0.67 128.04 30.38
44 INT90792 Localization of Il10 4 144 0.80 87.88 30.03
45 INT82882 Localization of Ccl2 1 61 0.80 41.96 28
46 INT11361 Gene_expression of SERPINE1 3 183 0.78 136.45 27.97
47 INT83708 Negative_regulation of MAPK1 3 156 0.57 84.93 27.85
48 INT177581 Regulation of Fig4 1 113 0.41 39.26 27.75
49 INT17331 Positive_regulation of JUN 1 132 0.69 60.4 27.03
50 INT12124 Gene_expression of MAPK1 8 141 0.75 82.4 25.58
51 INT130186 Gene_expression of Ccl5 14 101 0.74 79.96 25.01
52 INT93717 Gene_expression of Mmp3 4 85 0.78 33.95 24.89
53 INT141612 Gene_expression of Ccr1 1 92 0.77 72.09 24.14
54 INT10835 Regulation of IL8 1 79 0.49 53.04 24.14
55 INT55583 Localization of IFNA1 2 135 0.78 85.07 24.13
56 INT94335 Positive_regulation of CXCL10 2 71 0.58 50.69 23
57 INT71875 Localization of Nfkb1 2 92 0.78 48.13 22.94
58 INT84732 Positive_regulation of Hand2 2 81 0.69 62.07 22
59 INT14700 Regulation of IFNA1 1 111 0.45 66.16 21.52
60 INT43226 Gene_expression of Hivep3 1 75 0.71 30.53 21.14
61 INT171820 Localization of Fig4 1 144 0.65 27.38 20.88
62 INT52106 Negative_regulation of Localization of IL8 4 57 0.52 22.81 20.8
63 INT170444 Binding of Gopc 2 172 0.39 45.05 20.71
64 INT20379 Localization of Il4 1 85 0.73 51.22 20.55
65 INT86751 Negative_regulation of Il10 1 62 0.59 40.1 20.51
66 INT105021 Binding of GOPC 2 187 0.40 60.39 20.38
67 INT12265 Positive_regulation of IgG 2 168 0.63 104.89 19.76
68 INT157463 Gene_expression of CX3CL1 1 55 0.62 69.05 19.75
69 INT101188 Gene_expression of Rela 1 81 0.56 23.43 19.15
70 INT91462 Positive_regulation of Phosphorylation of MAPK1 4 99 0.67 40.28 18.99
71 INT10833 Regulation of Gene_expression of IL8 1 68 0.62 38.74 18.46
72 INT167679 Gene_expression of Ccr5 14 74 0.75 59.03 18.16
73 INT116950 Negative_regulation of MAPK8 1 103 0.57 44.48 17.53
74 INT94467 Positive_regulation of Hand1 3 71 0.58 59 16.96
75 INT109929 Phosphorylation of MAPK8 7 102 0.81 39.98 16.54
76 INT10834 Binding of IL8 1 65 0.48 41.66 16.53
77 INT22900 Positive_regulation of Cd4 2 126 0.67 82.77 16.43
78 INT104045 Regulation of Hand1 1 65 0.35 51.32 16.26
79 INT52107 Transcription of IL8 8 63 0.72 41.66 16.06
80 INT171666 Regulation of GOPC 1 117 0.39 40.41 15.47
81 INT170855 Negative_regulation of GOPC 1 188 0.38 70.92 15.41
82 INT1888 Protein_catabolism of F13A1 2 97 0.99 63.48 14.82
83 INT93482 Localization of Rela 3 56 0.78 24.52 14.82
84 INT5904 Localization of MPO 1 62 0.81 36.37 14.64
85 INT60197 Gene_expression of JUN 1 90 0.78 42.32 14.61
86 INT69952 Positive_regulation of IK 1 45 0.32 16.08 14.59
87 INT88544 Gene_expression of MMRN1 5 102 0.75 68.8 14.55
88 INT108480 Gene_expression of CCL21 1 53 0.77 37.87 14.42
89 INT72127 Protein_catabolism of MMRN1 7 68 0.52 56 14.13
90 INT80688 Positive_regulation of Positive_regulation of MAPK1 7 72 0.69 39.35 14.11
91 INT173505 Localization of Hand2 1 63 0.57 45.32 13.66
92 INT80685 Gene_expression of MAPK8 6 90 0.72 51.91 13.36
93 INT20378 Localization of Hand1 1 53 0.71 41.96 13.31
94 INT144646 Positive_regulation of Rela 1 53 0.67 27.78 13.2
95 INT20381 Localization of Il2 1 71 0.77 34.23 13.03
96 INT55255 Positive_regulation of Localization of Il6 2 48 0.69 24.88 12.76
97 INT2129 Positive_regulation of F2 1 83 0.70 58.95 12.63
98 INT89294 Gene_expression of Ccr3 1 53 0.68 43.9 12.62
99 INT94464 Negative_regulation of Hand1 1 44 0.41 31.5 12.39
100 INT170601 Positive_regulation of Gene_expression of GOPC 1 122 0.43 42.79 11.68
101 INT102272 Regulation of TH1L 2 41 0.44 30.89 11.63
102 INT69029 Gene_expression of PTPRC 1 127 0.75 74.26 11.57
103 INT176607 Gene_expression of Cx3cl1 1 27 0.75 19.51 11.32
104 INT75525 Negative_regulation of Positive_regulation of MAPK1 2 40 0.59 25.15 11.15
105 INT168409 Positive_regulation of Ccl5 7 47 0.64 45.84 10.83
106 INT4498 Gene_expression of F2 1 83 0.65 57.4 10.8
107 INT1087 Negative_regulation of Msr1 1 32 0.57 8.35 10.72
108 INT16449 Binding of IGHG3 1 67 0.48 39.55 10.59
109 INT86361 Positive_regulation of Positive_regulation of NOS1 1 39 0.53 18.93 10.42
110 INT27937 Gene_expression of Klkb1 1 35 0.55 1.86 10.08
111 INT107307 Transcription of IFNA1 1 30 0.52 18.16 9.61
112 INT94196 Negative_regulation of Phosphorylation of MAPK1 3 60 0.59 31.64 9.16
113 INT25381 Localization of Csf2 3 62 0.76 47.48 9.03
114 INT69264 Gene_expression of KIT 2 207 0.78 179.41 8.95
115 INT61264 Regulation of Jun 1 36 0.61 18.42 8.71
116 INT251636 Gene_expression of Csf2rb2 26 1 0.33 9.64 8.34
117 INT111533 Positive_regulation of Gene_expression of Nfkb1 1 27 0.52 17.32 7.89
118 INT80686 Positive_regulation of Positive_regulation of MAPK8 4 42 0.68 26.95 7.63
119 INT1120 Gene_expression of C3 3 33 0.67 22.86 7.56
120 INT17501 Negative_regulation of F2 1 70 0.58 32.23 7.51
121 INT14732 Positive_regulation of FN1 3 46 0.69 31.17 7.33
122 INT50212 Gene_expression of Ifx 4 33 0.75 32.17 7.26
123 INT44920 Negative_regulation of IK 1 18 0.41 9.9 7.16
124 INT153268 Positive_regulation of Ccr5 5 25 0.66 19 7.02
125 INT170381 Transcription of Gopc 1 59 0.60 15.96 6.82
126 INT181348 Localization of Ccl5 4 24 0.65 19.55 6.8
127 INT160562 Localization of Cd4 2 49 0.71 27.58 6.78
128 INT50255 Regulation of Cd4 1 39 0.49 29.73 6.77
129 INT11591 Gene_expression of IgG2a 1 53 0.65 23.14 6.73
130 INT25385 Positive_regulation of Localization of Il2 1 17 0.45 9.53 6.45
131 INT9695 Negative_regulation of Csf2 1 41 0.57 31.65 6.28
132 INT4561 Gene_expression of PLG 1 32 0.75 17.59 6.21
133 INT8106 Gene_expression of GGT1 1 31 0.75 18.65 6.1
134 INT39416 Gene_expression of Cd79a 6 81 0.64 45.17 6.08
135 INT75832 Positive_regulation of Positive_regulation of IL8 3 30 0.70 20.77 6.05
136 INT74422 Regulation of Localization of IL8 4 21 0.62 10.19 5.99
137 INT130111 Regulation of Positive_regulation of MAPK1 3 14 0.36 11.01 5.9
138 INT181406 Binding of Ccr5 1 16 0.45 17 5.78
139 INT132573 Negative_regulation of Gene_expression of TH1L 1 16 0.42 11.52 5.76
140 INT71779 Positive_regulation of Gene_expression of MAPK1 5 27 0.47 21.41 5.39
141 INT138157 Regulation of Mmp3 2 12 0.54 6.12 5.36
142 INT106189 Regulation of Il12a 1 18 0.44 12.4 5.3
143 INT109928 Negative_regulation of Positive_regulation of MAPK8 1 19 0.42 10.42 5.23
144 INT137179 Positive_regulation of CXCL9 2 11 0.65 7.73 5.11
145 INT181363 Regulation of Ccl5 2 16 0.46 13.65 5.09
146 INT75831 Positive_regulation of Transcription of IL8 4 21 0.63 13.56 4.98
147 INT181362 Negative_regulation of Ccl5 11 21 0.40 15.63 4.96
148 INT176614 Positive_regulation of Gene_expression of Ccl5 3 20 0.59 16.2 4.81
149 INT1539 Positive_regulation of MSMB 1 22 0.69 9.42 4.62
150 INT46350 Gene_expression of Msr1 10 32 0.65 29.39 4.55
151 INT181042 Binding of Ccl5 2 18 0.41 9.34 4.51
152 INT11635 Positive_regulation of Gene_expression of SERPINE1 1 35 0.68 24.57 4.26
153 INT109935 Positive_regulation of Phosphorylation of MAPK8 4 35 0.68 13.13 4.18
154 INT110181 Negative_regulation of Phosphorylation of MAPK8 1 20 0.57 9.43 4.06
155 INT101301 Gene_expression of Aif1 5 17 0.42 16.43 4.06
156 INT88545 Localization of MMRN1 1 21 0.78 16.67 4.01
157 INT106065 Negative_regulation of MAP2K1 1 27 0.57 12.69 3.97
158 INT132103 Positive_regulation of Gene_expression of MAPK8 4 26 0.46 16.54 3.94
159 INT68255 Regulation of Positive_regulation of IL8 1 12 0.41 5.71 3.91
160 INT86769 Positive_regulation of Gene_expression of Rbm39 1 11 0.25 5.6 3.8
161 INT123883 Positive_regulation of Gene_expression of Mmp3 1 16 0.60 4.42 3.74
162 INT18515 Gene_expression of Lipg 1 18 0.66 9.3 3.72
163 INT181378 Negative_regulation of Gene_expression of Ccl5 1 12 0.46 9.64 3.59
164 INT10106 Positive_regulation of Msr1 2 16 0.50 5.86 3.52
165 INT28528 Gene_expression of MSMB 5 25 0.65 7.66 3.49
166 INT143998 Binding of IK 1 11 0.34 2.44 3.42
167 INT5286 Gene_expression of ANTXR2 1 46 0.75 21.06 3.41
168 INT14994 Positive_regulation of Localization of MPO 1 12 0.70 6.85 3.37
169 INT170606 Regulation of Gene_expression of GOPC 1 31 0.37 6.08 3.31
170 INT33661 Regulation of Tbpl1 2 7 0.44 5.36 3.26
171 INT61500 Binding of FN1 7 39 0.48 27.33 3.13
172 INT180971 Protein_catabolism of GOPC 1 21 0.77 6.15 2.98
173 INT91432 Binding of MMRN1 2 23 0.36 9.79 2.95
174 INT68235 Positive_regulation of IgG2a 4 39 0.49 30.96 2.75
175 INT24902 Gene_expression of SP1 2 17 0.71 8.11 2.58
176 INT191017 Localization of Cd79a 3 28 0.56 13.94 2.55
177 INT174417 Gene_expression of Ccr4 1 5 0.42 3.77 2.49
178 INT190081 Gene_expression of Abca1 1 21 0.65 18.18 2.45
179 INT251633 Positive_regulation of Csf2rb2 6 1 0.26 2.64 2.44
180 INT65732 Binding of Msr1 3 9 0.47 7.28 2.42
181 INT114327 Positive_regulation of RAF1 2 26 0.51 20.87 2.32
182 INT4560 Protein_catabolism of PLG 4 18 0.96 11.64 2.32
183 INT97152 Protein_catabolism of COL1A1 2 11 0.74 8.03 2.3
184 INT181356 Positive_regulation of Gene_expression of Ccr5 3 11 0.66 8.3 2.24
185 INT24740 Positive_regulation of Cd79a 4 36 0.48 14.71 2.17
186 INT122890 Regulation of Gene_expression of Rbm39 1 5 0.13 1.96 2.17
187 INT77651 Negative_regulation of Transcription of IL8 1 8 0.43 4.48 2.16
188 INT175655 Regulation of MMRN1 1 16 0.12 9.96 2.12
189 INT93718 Protein_catabolism of Mmp3 1 9 0.73 4.32 2.11
190 INT51280 Gene_expression of Igkv11-125 1 5 0.11 2.54 2.11
191 INT25286 Localization of IL1RL1 1 7 0.56 3.17 2.07
192 INT39837 Positive_regulation of Cpn1 3 6 0.69 6.2 2.06
193 INT49250 Regulation of Atp6v0d2 2 5 0.08 1.54 2.04
194 INT109906 Localization of MAPK1 1 12 0.54 1.68 2.01
195 INT83709 Negative_regulation of Gene_expression of MAPK1 1 12 0.41 6.57 2.01
196 INT92056 Transcription of Il12b 1 8 0.69 4.75 1.95
197 INT61148 Regulation of Cd79a 1 13 0.51 6.95 1.9
198 INT251639 Positive_regulation of Gene_expression of Csf2rb2 4 1 0.21 1.73 1.66
199 INT61913 Binding of IgG2a 1 10 0.47 5.04 1.64
200 INT251238 Gene_expression of Lvs 11 35 0.32 29.41 1.59
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