J:BMC Mol Biol

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 1 0.02 1.86 1.8
2 INT55162 Binding of NFKB1 and RELA 10 1 0.30 2.82 1.18
3 INT199285 Tg(Foxn1)E1Hon Regulation of Gene_expression of Mapt 1 1 0.01 0.52 0.36
4 INT199286 Tg(Foxn1)E1Hon Regulation of Gene_expression of Oprm1 1 1 0.13 0.32 0.28
5 INT221955 Binding of ELAVL1 and CDK5R1 1 4 0.01 0.93 0.19
6 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 1 0.21 0.62 0.19
7 INT170585 PPARA Negative_regulation of DYM 1 1 0.03 0.07 0.14
8 INT199284 Binding of Polr2a and Vmn1r66 1 1 0.00 0.19 0.11
9 INT236266 Binding of Pgk1 and Ppia 1 1 0.13 0.71 0.11
10 INT221958 CDK5R1 Positive_regulation of Positive_regulation of CDK5 1 1 0.36 0.38 0.1
11 INT221959 Binding of CDK5 and CDK5R1 1 1 0.28 0.53 0.1
12 INT221954 Binding of CDK5 and CDK5R2 1 1 0.02 0.36 0.09
13 INT190044 Binding of Msh2 and Msh6 2 1 0.32 0.77 0.05
14 INT190050 Binding of Msh2 and Pms2 2 1 0.32 0.49 0.04
15 INT190046 Binding of Msh3 and Pms2 2 1 0.25 0.5 0.04
16 INT221952 UTS2R Regulation of Protein_catabolism of CDK5R1 1 1 0.10 0.3 0.04
17 INT221953 UTS2R Positive_regulation of Gene_expression of CDK5R1 1 1 0.16 0.23 0.04
18 INT221962 UTS2R Regulation of Gene_expression of CDK5R1 1 1 0.09 0.43 0.03
19 INT221963 ELAVL1 Regulation of Gene_expression of CDK5R1 1 1 0.01 0.58 0.03
20 INT221961 Binding of ELAVL1 and UTS2R 1 1 0.00 0.26 0.03
21 INT172716 Binding of BCL3 and NFKB1 1 2 0.06 0.15 0.03
22 INT207817 Negative_regulation of Parp1 Positive_regulation of Atm 1 2 0.53 0.2 0
23 INT207815 Parp1 Negative_regulation of Phosphorylation of Atm 1 1 0.42 0.15 0
24 INT207816 Parp1 Regulation of Positive_regulation of Atm 1 1 0.51 0.21 0
25 INT221960 Binding of C4B and ELAVL1 1 1 0.00 0.15 0
26 INT170586 CD40 Negative_regulation of Positive_regulation of RELA 1 2 0.12 0.24 0
27 INT170587 GOPC Regulation of Gene_expression of ICAM1 1 1 0.13 0 0
28 INT170590 RELA Negative_regulation of Gene_expression of ICAM1 1 1 0.42 0.49 0
29 INT170588 RELA Regulation of Gene_expression of ICAM1 1 2 0.26 0 0
30 INT230272 RAD54L Regulation of RAD54B 1 1 0.01 0 0
31 INT221957 Binding of UTS2R and GOPC 1 1 0.02 0.08 0
32 INT170589 NFKB1 Regulation of Gene_expression of ICAM1 1 1 0.27 0 0
33 INT207813 Atm Regulation of Gene_expression of Parp1 1 1 0.44 0.31 0
34 INT207814 Negative_regulation of Parp1 Positive_regulation of Positive_regulation of Atm 1 1 0.53 0.08 0
35 INT207812 Binding of Parp1 and Atm 1 12 0.54 0.99 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5895 Gene_expression of Oprm1 12 525 0.78 120.67 407.29
2 INT5059 Positive_regulation of TNF 2 1050 0.70 896.51 322.81
3 INT6481 Binding of TNF 1 624 0.48 510.2 214.82
4 INT16259 Positive_regulation of Bdnf 1 336 0.70 183.48 209.82
5 INT26472 Regulation of Oprm1 1 191 0.62 35.84 173.1
6 INT120811 Gene_expression of Gopc 2 1174 0.59 428.49 150.55
7 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1 1138 0.72 311.58 119.18
8 INT50674 Gene_expression of PTGS2 2 459 0.78 253.33 118.51
9 INT170025 Gene_expression of Fig4 1 588 0.67 183.27 113.32
10 INT90091 Gene_expression of GOPC 8 967 0.67 366.22 103.6
11 INT48767 Negative_regulation of NOS1 1 312 0.59 154.25 90.32
12 INT48408 Gene_expression of ICAM1 62 494 0.78 340.08 88.6
13 INT54571 Positive_regulation of NFKB1 1 263 0.70 138.99 87.32
14 INT171145 Positive_regulation of Fig4 1 274 0.59 93.55 69.81
15 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
16 INT1536 Negative_regulation of NA 3 244 0.55 52.67 59.79
17 INT6623 Gene_expression of NA 3 231 0.78 45.78 59.36
18 INT8732 Positive_regulation of Gene_expression of Oprm1 1 76 0.70 22.59 58.83
19 INT68813 Transcription of Oprm1 6 93 0.71 20.11 57.65
20 INT157666 Positive_regulation of GOPC 2 335 0.60 120.19 42.75
21 INT4449 Positive_regulation of NA 2 179 0.55 40.26 37.82
22 INT62827 Positive_regulation of ICAM1 2 184 0.70 180.95 36.28
23 INT68973 Positive_regulation of Mmp9 1 89 0.52 58.56 30.04
24 INT6660 Positive_regulation of Jun 1 148 0.69 67.58 29.73
25 INT651 Positive_regulation of PTGS1 1 93 0.69 37.27 29.18
26 INT15610 Localization of GOPC 1 223 0.65 68.26 28.7
27 INT17331 Positive_regulation of JUN 1 132 0.69 60.4 27.03
28 INT72677 Regulation of Gene_expression of Oprm1 1 45 0.62 13.95 26.75
29 INT66025 Gene_expression of Itgam 2 61 0.78 31.26 26.08
30 INT76743 Gene_expression of Slc6a4 5 55 0.76 13.53 24.9
31 INT55170 Gene_expression of NFKB1 2 97 0.77 52.75 23.04
32 INT171820 Localization of Fig4 2 144 0.65 27.38 20.88
33 INT63340 Positive_regulation of Gene_expression of ICAM1 18 109 0.70 90.82 20.61
34 INT17848 Binding of PTGS2 2 70 0.46 32.1 20.6
35 INT105021 Binding of GOPC 4 187 0.40 60.39 20.38
36 INT80755 Gene_expression of CD40 25 88 0.75 53.68 17.86
37 INT62826 Negative_regulation of Gene_expression of ICAM1 15 75 0.58 46.39 17.72
38 INT6791 Binding of NA 1 55 0.46 5.36 17.59
39 INT170855 Negative_regulation of GOPC 1 188 0.38 70.92 15.41
40 INT10870 Regulation of IgG 1 67 0.59 43.27 12.74
41 INT170601 Positive_regulation of Gene_expression of GOPC 1 122 0.43 42.79 11.68
42 INT60198 Binding of JUN 1 54 0.48 11.56 10.27
43 INT63341 Negative_regulation of ICAM1 1 42 0.59 30.45 9.5
44 INT63338 Regulation of Gene_expression of ICAM1 6 42 0.62 28.26 9.06
45 INT49866 Negative_regulation of Parp1 12 53 0.58 35.37 8.84
46 INT66213 Localization of RELA 16 63 0.78 14.71 8.77
47 INT64815 Binding of Jun 1 49 0.48 21.47 8.59
48 INT97331 Positive_regulation of Timp1 1 20 0.45 13.32 8.57
49 INT123813 Positive_regulation of Parp1 7 74 0.70 65.36 8.56
50 INT93003 Binding of CD40 1 28 0.47 20.25 7.13
51 INT170381 Transcription of Gopc 2 59 0.60 15.96 6.82
52 INT17618 Gene_expression of B2M 3 36 0.66 16.39 6.68
53 INT8595 Localization of Mapt 22 26 0.73 6.81 6.41
54 INT11258 Gene_expression of Gnas 3 58 0.58 21.6 6.33
55 INT93359 Positive_regulation of Trp53 2 90 0.70 69.77 6.24
56 INT172084 Positive_regulation of Binding of TNF 1 21 0.50 15.31 6.06
57 INT44608 Gene_expression of C2 4 45 0.75 15.84 5.05
58 INT109972 Phosphorylation of Trp53 2 13 0.80 6.15 4.68
59 INT75627 Gene_expression of Mapt 21 41 0.75 22.1 4.58
60 INT170604 Negative_regulation of Gene_expression of GOPC 2 50 0.35 12.71 4.51
61 INT55171 Gene_expression of RELA 42 80 0.75 17.17 4.47
62 INT198736 Binding of Sp3 2 23 0.40 4.77 4.42
63 INT41942 Gene_expression of A2m 4 9 0.36 9.98 3.96
64 INT64817 Positive_regulation of Binding of Jun 1 16 0.69 6.78 3.81
65 INT71602 Negative_regulation of Trp53 1 84 0.59 67.77 3.68
66 INT79231 Positive_regulation of Gene_expression of NFKB1 1 18 0.67 9.16 3.66
67 INT23886 Positive_regulation of Gene_expression of NA 1 15 0.40 3.69 3.59
68 INT73557 Positive_regulation of RELA 39 57 0.46 8.7 3.43
69 INT62061 Gene_expression of TRGC1 1 32 0.69 17.43 3.37
70 INT93915 Positive_regulation of Gene_expression of CD40 1 14 0.44 12.45 3.35
71 INT170606 Regulation of Gene_expression of GOPC 1 31 0.37 6.08 3.31
72 INT127455 Positive_regulation of Gene_expression of Slc6a4 4 9 0.59 5.62 3.2
73 INT123409 Binding of Sp1 1 20 0.39 3.18 3.15
74 INT123815 Gene_expression of Parp1 5 42 0.67 27.82 3.02
75 INT199255 Binding of Rest 2 14 0.41 1.43 2.94
76 INT30051 Gene_expression of Vmn1r66 25 2 0.22 11.18 2.78
77 INT19492 Regulation of B2M 1 16 0.60 10.97 2.55
78 INT192541 Gene_expression of Tg(Foxn1)E1Hon 17 20 0.20 8.98 2.4
79 INT192980 Negative_regulation of NeuN 1 14 0.36 5.24 2.32
80 INT29094 Binding of C3 1 39 0.37 12.65 2.27
81 INT74628 Positive_regulation of Mmp7 2 8 0.25 4.19 2.27
82 INT124138 Gene_expression of YWHAZ 1 9 0.62 4.04 2.21
83 INT4125 Gene_expression of Gusb 1 6 0.62 2.32 2.13
84 INT110925 Positive_regulation of Positive_regulation of JUN 1 14 0.49 6.22 1.98
85 INT73335 Gene_expression of ACTB 1 21 0.58 5.62 1.94
86 INT34714 Positive_regulation of B2m 4 3 0.66 2.78 1.86
87 INT131818 Binding of Parp1 4 14 0.46 8.74 1.76
88 INT55169 Binding of RELA 17 40 0.36 4.91 1.74
89 INT41639 Positive_regulation of A2m 4 7 0.46 4.52 1.74
90 INT189911 Gene_expression of Aym1 4 3 0.01 3.97 1.74
91 INT108875 Positive_regulation of Localization of RELA 4 9 0.49 1.43 1.72
92 INT170605 Gene_expression of RELB 1 12 0.65 8 1.7
93 INT134733 Gene_expression of Dab1 1 6 0.66 0.56 1.61
94 INT199263 Regulation of Vmn1r66 8 1 0.06 2.78 1.61
95 INT192542 Regulation of Tg(Foxn1)E1Hon 7 2 0.16 2.18 1.59
96 INT88726 Gene_expression of HPRT1 1 36 0.78 10.12 1.58
97 INT102428 Binding of C2 2 17 0.32 5.12 1.58
98 INT114862 Gene_expression of BEST1 1 16 0.65 12.14 1.53
99 INT16227 Regulation of Rit2 2 3 0.62 0.24 1.43
100 INT172953 Binding of Trp53 1 33 0.37 20.76 1.41
101 INT114969 Gene_expression of CDK5R1 20 3 0.75 11.24 1.33
102 INT110252 Positive_regulation of Gene_expression of RELA 19 29 0.49 6.36 1.31
103 INT46384 Binding of TRGC1 4 16 0.41 4.87 1.28
104 INT111277 Negative_regulation of Gene_expression of C2 1 7 0.42 2.44 1.2
105 INT55315 Gene_expression of Tbp 1 32 0.74 14.6 1.17
106 INT199272 Regulation of Aym1 3 1 0.00 1.42 1.16
107 INT119348 Binding of IKBKG 1 7 0.15 4.03 1.14
108 INT4124 Regulation of Gusb 1 3 0.22 1.05 1.11
109 INT36451 Gene_expression of G6PD 10 26 0.75 7.2 1.09
110 INT123816 Positive_regulation of Gene_expression of Parp1 2 9 0.50 6.64 1.04
111 INT200107 Gene_expression of SDHA 1 9 0.37 5.29 1.02
112 INT116797 Gene_expression of Osmr 1 9 0.73 1.12 1
113 INT121361 Gene_expression of Rit2 1 8 0.33 1.08 0.95
114 INT111279 Positive_regulation of Gene_expression of C2 1 8 0.49 1.06 0.94
115 INT52454 Localization of Tbp 1 7 0.76 2.53 0.91
116 INT124884 Gene_expression of Rpl4 1 3 0.53 1.56 0.9
117 INT195946 Gene_expression of Hprt1 1 9 0.75 1.03 0.89
118 INT127452 Positive_regulation of CDK5 3 5 0.32 1.88 0.87
119 INT131066 Binding of C6 1 4 0.31 1.81 0.86
120 INT184678 Regulation of Uts2r 1 7 0.14 2.57 0.85
121 INT221967 Protein_catabolism of C2 1 2 0.08 1.06 0.83
122 INT4103 Regulation of G6PD 3 6 0.60 0.78 0.82
123 INT219358 Gene_expression of CDK5 3 9 0.58 5.65 0.81
124 INT168561 Positive_regulation of Trpm2 2 2 0.66 1.38 0.81
125 INT61971 Gene_expression of TBP 1 9 0.65 5.14 0.8
126 INT77663 Positive_regulation of CDK5R1 1 3 0.67 0.43 0.79
127 INT296647 Gene_expression of Trpm2 5 1 0.64 2.94 0.79
128 INT10017 Gene_expression of REL 1 8 0.65 2.01 0.78
129 INT170603 Negative_regulation of Gene_expression of CD40 1 5 0.32 2.18 0.78
130 INT71950 Positive_regulation of Binding of PTGS2 2 2 0.31 0.31 0.74
131 INT199253 Transcription of Vmn1r66 19 1 0.07 7.33 0.73
132 INT28118 Binding of Atm 4 13 0.38 12.24 0.68
133 INT235746 Positive_regulation of Casp2 4 2 0.04 2.67 0.67
134 INT77662 Regulation of CDK5R1 3 2 0.60 1.93 0.63
135 INT108874 Regulation of Localization of RELA 2 5 0.44 1.09 0.61
136 INT221978 Regulation of Gene_expression of CDK5R1 13 1 0.59 5.08 0.61
137 INT93358 Negative_regulation of Positive_regulation of Trp53 1 9 0.41 3.95 0.6
138 INT74507 Protein_catabolism of PRTN3 1 4 0.87 1.14 0.52
139 INT124892 Negative_regulation of Ppia 1 3 0.15 0.93 0.52
140 INT164518 Gene_expression of PPIA 1 7 0.75 3.92 0.5
141 INT210300 Gene_expression of ELAVL4 2 10 0.65 5.14 0.49
142 INT30053 Positive_regulation of Vmn1r66 8 2 0.17 2.26 0.47
143 INT211584 Gene_expression of Dmpk 1 32 0.73 12.28 0.46
144 INT174229 Binding of CPA1 2 3 0.07 2 0.46
145 INT236260 Gene_expression of Actb 3 1 0.59 1.42 0.41
146 INT56815 Gene_expression of ckrtgr 1 6 0.01 1.7 0.4
147 INT28573 Positive_regulation of Rit1 2 5 0.33 3.46 0.4
148 INT199262 Negative_regulation of Localization of Mapt 2 3 0.41 1.19 0.4
149 INT199257 Positive_regulation of Tg(Foxn1)E1Hon 6 1 0.18 1.14 0.4
150 INT296644 Transcription of Trpm2 2 1 0.66 1.15 0.39
151 INT144275 Negative_regulation of Atm 1 9 0.59 8.48 0.36
152 INT221973 Negative_regulation of CDK5 2 4 0.57 2.26 0.36
153 INT199261 Negative_regulation of Gene_expression of Mapt 2 1 0.06 1.25 0.36
154 INT296651 Negative_regulation of Casp2 1 2 0.21 1.75 0.35
155 INT236258 Regulation of Gene_expression of Actb 2 1 0.34 1.09 0.35
156 INT130453 Gene_expression of ELAVL2 2 6 0.36 2.28 0.34
157 INT199265 Positive_regulation of Gene_expression of Mapt 1 3 0.67 1.34 0.34
158 INT211586 Regulation of DMPK 1 6 0.31 2.11 0.33
159 INT171530 Gene_expression of Tfdp2 1 2 0.06 0.13 0.33
160 INT73555 Negative_regulation of RELA 1 5 0.41 0.57 0.32
161 INT85944 Binding of ELAVL1 4 5 0.07 1.11 0.31
162 INT208851 Gene_expression of Ppia 1 6 0.47 2.63 0.3
163 INT296645 Positive_regulation of Gene_expression of Trpm2 2 1 0.48 1.25 0.3
164 INT199277 Regulation of Gene_expression of Mapt 2 1 0.08 1.12 0.3
165 INT296649 Gene_expression of Ppm1b 1 1 0.01 0.65 0.29
166 INT199260 Regulation of Gene_expression of Tg(Foxn1)E1Hon 3 1 0.12 1.19 0.29
167 INT138020 Binding of Osmr 1 2 0.21 0.25 0.27
168 INT156901 Regulation of ACTB 1 8 0.28 3.76 0.26
169 INT39972 Gene_expression of CPA1 1 7 0.65 3.17 0.26
170 INT197121 Positive_regulation of Atm 20 24 0.69 6.81 0.25
171 INT170600 Negative_regulation of Gene_expression of RELA 15 16 0.39 1.29 0.25
172 INT170596 Regulation of RELA 1 4 0.41 0.39 0.25
173 INT35719 Gene_expression of Atm 2 34 0.78 15.75 0.24
174 INT199276 Binding of Tbp 1 12 0.46 2.67 0.24
175 INT88725 Regulation of HPRT1 1 5 0.62 1.28 0.24
176 INT199251 Gene_expression of Pou2f1 1 1 0.35 0 0.23
177 INT199279 Gene_expression of Ltnr4 1 1 0.03 0 0.23
178 INT170594 Regulation of Gene_expression of RELA 4 6 0.41 0.15 0.22
179 INT170607 Positive_regulation of Positive_regulation of RELA 2 4 0.46 1.49 0.21
180 INT296641 Binding of Polr2f 1 2 0.10 1.09 0.21
181 INT170602 Positive_regulation of Binding of RELA 4 5 0.46 0.32 0.2
182 INT199269 Binding of Qsox1 1 2 0.10 0 0.2
183 INT207809 Positive_regulation of Negative_regulation of Parp1 1 2 0.50 1.01 0.2
184 INT219375 Localization of CDK5 1 4 0.52 2.8 0.19
185 INT322321 Gene_expression of PGK1 1 4 0.65 1.07 0.19
186 INT221974 Phosphorylation of CDK5 2 1 0.56 0.99 0.19
187 INT236255 Regulation of Actb 1 1 0.47 0.59 0.18
188 INT175532 Localization of Parp1 3 9 0.74 5.73 0.17
189 INT169875 Negative_regulation of Ercc1 1 3 0.43 3.07 0.17
190 INT296650 Gene_expression of Casp2 1 2 0.30 1.49 0.17
191 INT236247 Regulation of Gene_expression of Ppia 1 1 0.21 0.56 0.17
192 INT296646 Transcription of Casp2 1 1 0.03 0.71 0.17
193 INT199256 Transcription of Tg(Foxn1)E1Hon 12 1 0.19 4.34 0.17
194 INT183817 Localization of BEST1 1 6 0.26 5.22 0.16
195 INT23890 Binding of CDK5R1 2 2 0.36 0.23 0.16
196 INT199254 Positive_regulation of Gene_expression of Vmn1r66 8 1 0.05 3.45 0.16
197 INT221972 Regulation of CDK5 2 1 0.42 1.87 0.16
198 INT207805 Negative_regulation of Phosphorylation of Trp53 1 2 0.18 0.98 0.15
199 INT235755 Regulation of Ppm1b 1 1 0.20 1.4 0.15
200 INT199259 Regulation of Gene_expression of Vmn1r66 1 1 0.04 0.57 0.15
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