J:BMC Pediatr

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT170654 Binding of Ntf3 and Ngf 1 4 0.38 1.66 1.54
2 INT170655 Binding of Csf2 and Ngf 1 3 0.36 1.25 1.18
3 INT170653 Ngf Regulation of Csf2 1 2 0.34 1.11 1.05
4 INT170658 Binding of Ntf3 and Csf2 1 2 0.33 0.8 0.74
5 INT333476 IL12B Positive_regulation of Localization of AFP 1 1 0.03 0.26 0.57
6 INT333477 CXCL10 Positive_regulation of TH1L 1 1 0.14 0.32 0.56
7 INT170656 Ntf3 Positive_regulation of Csf2 1 1 0.35 1.46 0.44
8 INT170657 Ntf3 Regulation of Csf2 1 1 0.31 0.46 0.43
9 INT174699 Binding of Tlr2 and Tlr3 3 2 0.14 0.66 0.35
10 INT298733 INS Regulation of ACSBG1 1 1 0.00 0.97 0.05
11 INT298734 USE1 Regulation of ACSBG1 1 1 0.00 0.97 0.05
12 INT353910 Binding of CRP and UROD 1 1 0.06 0.34 0
13 INT191540 Binding of ABCA3 and GOPC 1 1 0.03 0.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 2 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 6 1575 0.78 1135.66 424.22
3 INT76660 Gene_expression of Trpv1 1 691 0.78 329.46 386.42
4 INT5680 Gene_expression of Ngf 10 530 0.78 264.29 310.56
5 INT9659 Gene_expression of Il6 2 991 0.78 715.11 265.57
6 INT68684 Gene_expression of VEGFA 1 2371 0.78 1742.52 259.2
7 INT11377 Positive_regulation of Ngf 9 331 0.70 206.5 238
8 INT626 Localization of CALCA 1 289 0.81 125.39 221.15
9 INT528 Gene_expression of Prl 1 693 0.78 217.18 192.2
10 INT10194 Positive_regulation of IL6 3 702 0.70 600.62 183.38
11 INT15516 Gene_expression of Crp 1 711 0.77 615.33 173.09
12 INT867 Gene_expression of IFNA1 3 930 0.78 594.85 168.03
13 INT15515 Positive_regulation of Crp 1 700 0.70 604.24 150.15
14 INT5116 Gene_expression of IL2 1 670 0.78 291.13 146.69
15 INT2867 Gene_expression of CALCA 1 247 0.78 78.78 138.47
16 INT7533 Gene_expression of Tlr4 1 720 0.78 343.22 121.57
17 INT8243 Positive_regulation of Il6 2 451 0.70 358.24 119.28
18 INT17612 Gene_expression of CRP 13 676 0.78 580.61 119.03
19 INT9235 Negative_regulation of Gene_expression of TNF 1 346 0.59 252.98 118.61
20 INT3038 Gene_expression of INS 2 1583 0.78 1174.16 107.01
21 INT18009 Positive_regulation of CRP 8 518 0.70 553.03 103.74
22 INT90091 Gene_expression of GOPC 2 967 0.67 366.22 103.6
23 INT11587 Gene_expression of CSF2 2 645 0.78 544.38 93.89
24 INT16254 Positive_regulation of Gene_expression of Ngf 3 144 0.70 80.61 82.08
25 INT749 Gene_expression of HLA-B 2 341 0.75 224.12 77.37
26 INT12001 Regulation of Ngf 6 97 0.62 54.64 76.25
27 INT56298 Gene_expression of IL4 1 306 0.78 182.18 72.92
28 INT3034 Localization of Ngf 2 126 0.81 50.81 72.84
29 INT79494 Positive_regulation of Gene_expression of VEGFA 1 577 0.70 442.94 69.73
30 INT6761 Binding of CALCA 3 100 0.48 26.71 62.05
31 INT39153 Positive_regulation of PTGS2 1 182 0.70 96.16 60.6
32 INT16258 Gene_expression of Ntf3 10 121 0.78 53.93 59.03
33 INT46637 Gene_expression of CXCL10 7 172 0.78 121.94 57.74
34 INT9408 Positive_regulation of Crp 1 296 0.69 242.27 57.35
35 INT251 Regulation of INS 1 398 0.62 232.47 55.04
36 INT8490 Negative_regulation of CALCA 1 87 0.59 29.73 51.34
37 INT1199 Positive_regulation of INS 2 579 0.70 399.64 50.43
38 INT145266 Gene_expression of IL17A 1 154 0.75 109.83 45.33
39 INT11406 Positive_regulation of Localization of CALCA 1 49 0.70 20.64 42.8
40 INT11939 Negative_regulation of Il6 1 138 0.59 87.46 41.24
41 INT957 Positive_regulation of GHRH 1 136 0.70 36.84 40.52
42 INT52732 Negative_regulation of CRP 3 169 0.59 138.47 40.33
43 INT3758 Gene_expression of ALB 1 326 0.78 184.65 38.75
44 INT65889 Gene_expression of RETNLB 1 73 0.34 60.98 38.3
45 INT16323 Gene_expression of pr 2 62 0.66 36.14 38.26
46 INT11439 Positive_regulation of Csf2 7 105 0.69 62.63 37.77
47 INT72651 Gene_expression of TH1L 1 114 0.75 80.15 35.15
48 INT6105 Positive_regulation of IL2 3 133 0.69 82.76 34.67
49 INT6302 Binding of IFNA1 1 196 0.48 133.85 32.73
50 INT22939 Gene_expression of Csf2 5 164 0.78 85.1 32.22
51 INT56809 Binding of Tlr4 2 184 0.48 106.02 31.18
52 INT8027 Regulation of Gene_expression of Ngf 1 34 0.62 26.32 31.16
53 INT9993 Positive_regulation of Gene_expression of IL2 1 131 0.69 46.27 30.04
54 INT23463 Positive_regulation of Gene_expression of CALCA 2 47 0.70 18.14 28.76
55 INT15610 Localization of GOPC 1 223 0.65 68.26 28.7
56 INT52722 Localization of RETNLB 2 54 0.38 48.63 27.98
57 INT100861 Binding of CRP 2 179 0.48 175.2 26.45
58 INT130176 Positive_regulation of Gene_expression of CRP 4 125 0.66 137.06 25.9
59 INT2614 Gene_expression of CGA 2 187 0.78 105.89 24.77
60 INT23937 Gene_expression of EDNRA 5 103 0.65 55.63 24.67
61 INT141612 Gene_expression of Ccr1 1 92 0.77 72.09 24.14
62 INT55583 Localization of IFNA1 1 135 0.78 85.07 24.13
63 INT8518 Localization of Ifng 2 53 0.81 36.68 24.13
64 INT250 Regulation of GHRH 1 65 0.61 17.46 23.19
65 INT94335 Positive_regulation of CXCL10 2 71 0.58 50.69 23
66 INT11659 Gene_expression of COL2A1 6 164 0.78 78.49 22.58
67 INT142594 Gene_expression of Tlr2 1 165 0.78 139.73 22.26
68 INT23257 Regulation of CRP 4 127 0.62 100.05 21.87
69 INT3589 Positive_regulation of SCN5A 2 101 0.57 46.01 21.73
70 INT14700 Regulation of IFNA1 1 111 0.45 66.16 21.52
71 INT48692 Binding of VEGFA 1 345 0.48 210.3 21.31
72 INT5328 Positive_regulation of CD4 1 191 0.69 133.43 21.31
73 INT96269 Positive_regulation of Mcpt1 1 71 0.61 52.38 20.4
74 INT65907 Negative_regulation of Gene_expression of Ngf 1 36 0.59 19.5 20.03
75 INT7581 Binding of ADHD1 3 132 0.46 135.1 19.73
76 INT138696 Positive_regulation of Ccl2 1 57 0.67 59.57 19.58
77 INT756 Gene_expression of C3 1 138 0.75 100.6 19.2
78 INT15470 Regulation of CPP 3 42 0.48 26.1 18.25
79 INT6782 Gene_expression of SCN5A 13 156 0.78 33.13 17.88
80 INT871 Negative_regulation of Gene_expression of Prl 1 53 0.58 18.89 17.79
81 INT86673 Positive_regulation of Bcl2 1 77 0.70 57.74 17.37
82 INT2120 Gene_expression of CD79A 1 159 0.78 111.69 17.16
83 INT38056 Localization of Crp 1 71 0.78 53.14 17.03
84 INT69203 Positive_regulation of Ntf3 7 43 0.66 19.16 16.49
85 INT170335 Gene_expression of INCENP 1 176 0.54 91.62 15.31
86 INT106745 Localization of CRP 1 65 0.81 66.44 15.21
87 INT73916 Gene_expression of Esr1 1 58 0.77 26.59 15.15
88 INT34590 Gene_expression of ALPP 1 199 0.75 89.85 15.1
89 INT75540 Positive_regulation of TH1L 1 62 0.67 43.45 15.02
90 INT10709 Negative_regulation of CD4 1 106 0.59 95.6 14.89
91 INT20665 Gene_expression of ACE 2 87 0.78 51.71 14.19
92 INT70265 Regulation of MRI1 1 42 0.39 30.95 14.18
93 INT18720 Localization of Csf2 1 72 0.67 13.65 13.41
94 INT14572 Binding of INS 2 205 0.48 175.43 13.38
95 INT1125 Positive_regulation of IGHG3 2 130 0.69 112.07 13.18
96 INT75224 Positive_regulation of Gene_expression of Ntf3 3 23 0.69 11.79 13.08
97 INT16256 Regulation of Ntf3 4 15 0.49 9.75 13.07
98 INT3521 Regulation of Csf2 1 38 0.54 11.09 12.73
99 INT4137 Positive_regulation of C3 1 73 0.69 48.57 12.63
100 INT149985 Gene_expression of Tlr9 1 32 0.75 29.83 11.86
101 INT4605 Negative_regulation of Gene_expression of INS 1 220 0.58 139.66 10.75
102 INT11936 Positive_regulation of Positive_regulation of Il6 1 34 0.50 26.85 10.59
103 INT144689 Regulation of RCT 1 49 0.53 25.91 9.6
104 INT137181 Gene_expression of CXCL9 6 25 0.65 13.09 9.56
105 INT75997 Positive_regulation of Localization of Ngf 2 14 0.69 7.78 9.41
106 INT140224 Localization of Ccl2 1 32 0.72 26.91 9.39
107 INT6510 Gene_expression of AFP 2 130 0.78 119.2 9.19
108 INT1118 Gene_expression of C6orf25 1 73 0.77 47.24 9.1
109 INT86672 Negative_regulation of Bcl2 2 50 0.53 34.16 8.37
110 INT6810 Gene_expression of ENO2 2 70 0.78 54.8 8.35
111 INT148703 Gene_expression of NOVA2 1 73 0.65 18.05 8.3
112 INT86705 Gene_expression of BTG3 1 41 0.65 37.29 8.29
113 INT16131 Negative_regulation of GBE1 1 37 0.30 10.32 8.15
114 INT25152 Gene_expression of SAA1 2 37 0.75 53.56 8.07
115 INT88868 Binding of MCS 4 45 0.40 37.43 7.98
116 INT71689 Localization of Ntf3 2 23 0.73 11.1 7.91
117 INT18524 Regulation of Gene_expression of IFNA1 1 37 0.44 18.79 7.62
118 INT153300 Negative_regulation of Gene_expression of CRP 2 48 0.58 39.97 7.58
119 INT6906 Negative_regulation of SCN5A 2 64 0.43 20.64 7.3
120 INT1123 Positive_regulation of CD79A 2 74 0.70 51.96 7.14
121 INT22834 Negative_regulation of CYP21A2 2 28 0.58 23.07 7.13
122 INT195442 Gene_expression of FIG4 2 23 0.65 5.13 6.92
123 INT14903 Negative_regulation of SOD1 1 81 0.57 42.02 6.91
124 INT68279 Positive_regulation of Gene_expression of Csf2 2 30 0.67 16.31 6.88
125 INT10094 Negative_regulation of ALPP 2 36 0.37 20.45 6.45
126 INT92662 Negative_regulation of Gene_expression of Ntf3 1 9 0.57 7.44 6.22
127 INT24961 Positive_regulation of Defb22 1 8 0.03 3.56 6.04
128 INT1126 Negative_regulation of CD79A 1 46 0.59 31.07 6
129 INT54602 Regulation of MCS 2 22 0.24 10.41 5.75
130 INT20280 Positive_regulation of Esr1 1 32 0.69 18.37 5.69
131 INT41892 Gene_expression of HBM 2 48 0.64 28.32 5.64
132 INT16257 Regulation of Gene_expression of Ntf3 1 8 0.43 4 5.63
133 INT95048 Negative_regulation of ADHD1 2 61 0.51 56.01 5.62
134 INT69350 Gene_expression of RAC1 1 23 0.77 12.16 5.54
135 INT35536 Negative_regulation of CAT 1 26 0.57 14.39 5.38
136 INT23598 Binding of SCN5A 1 32 0.40 16 5.35
137 INT30209 Localization of SCN5A 3 24 0.72 7.95 5.35
138 INT174688 Binding of Tlr2 2 45 0.42 36.65 5.25
139 INT92234 Regulation of CXCL10 1 15 0.42 8.37 5.09
140 INT71418 Binding of CES1 2 42 0.40 29.78 5.01
141 INT104391 Gene_expression of Tnpo1 1 12 0.65 9.61 4.87
142 INT49805 Positive_regulation of MUC1 2 56 0.70 44.5 4.56
143 INT7083 Positive_regulation of HBM 1 35 0.66 20.96 4.3
144 INT45975 Positive_regulation of SAA1 6 17 0.67 19.7 4.15
145 INT168418 Positive_regulation of RCT 1 32 0.55 20.2 4.07
146 INT158595 Gene_expression of Tlr3 1 25 0.69 12.09 4.07
147 INT61118 Gene_expression of Nefl 1 11 0.75 4.02 4.02
148 INT25464 Binding of SAA1 1 11 0.42 6.89 3.72
149 INT136106 Gene_expression of DNMT3B 1 30 0.58 8.43 3.7
150 INT158596 Binding of Tlr3 2 24 0.47 11.66 3.69
151 INT174477 Negative_regulation of IL7 1 11 0.47 10.35 3.69
152 INT155011 Negative_regulation of IL17A 1 8 0.54 6.43 3.64
153 INT67468 Regulation of SCN5A 1 27 0.44 4.4 3.47
154 INT176386 Positive_regulation of Gene_expression of TH1L 1 14 0.32 9.17 3.4
155 INT151123 Negative_regulation of Gene_expression of Csf2 1 21 0.53 21.76 3.22
156 INT8477 Negative_regulation of AFP 1 35 0.58 31.52 3.1
157 INT43907 Binding of CD79A 1 28 0.48 28.11 3.04
158 INT16287 Positive_regulation of NOVA2 1 25 0.49 6.62 3.01
159 INT16130 Binding of IGF1 1 67 0.48 27.43 2.95
160 INT220335 Gene_expression of UROD 3 34 0.54 24.53 2.89
161 INT31541 Regulation of Esr1 2 15 0.54 4.12 2.82
162 INT181267 Gene_expression of USE1 1 12 0.32 7.6 2.7
163 INT20551 Negative_regulation of COL2A1 1 31 0.55 21.98 2.66
164 INT96693 Binding of COL2A1 2 45 0.46 37.11 2.61
165 INT174687 Regulation of Positive_regulation of Il6 1 10 0.61 9.07 2.61
166 INT165841 Gene_expression of BPIFA4P 1 17 0.65 6.48 2.38
167 INT106307 Positive_regulation of UROD 5 27 0.49 16.63 2.19
168 INT92648 Positive_regulation of IL12B 1 7 0.20 4.55 2.19
169 INT3533 Binding of REN 1 24 0.37 10.84 2.16
170 INT98652 Positive_regulation of Localization of Ntf3 2 2 0.40 1.42 2.15
171 INT226492 Negative_regulation of IL13 1 11 0.28 7.17 2.04
172 INT86671 Negative_regulation of Positive_regulation of Bcl2 1 6 0.57 3.83 2.03
173 INT146793 Positive_regulation of Tp53 3 30 0.70 32.93 1.94
174 INT24453 Binding of NLRP3 1 18 0.48 13.7 1.93
175 INT16385 Regulation of C3 1 20 0.41 9.98 1.92
176 INT11136 Positive_regulation of Localization of Ifng 1 4 0.49 3.13 1.89
177 INT131916 Negative_regulation of ALPL 4 10 0.42 9.33 1.8
178 INT183753 Regulation of HBM 1 24 0.39 13.13 1.79
179 INT160814 Gene_expression of Il6ra 1 15 0.07 9.61 1.73
180 INT322198 Positive_regulation of AMCN 6 13 0.43 7.79 1.73
181 INT127145 Gene_expression of SET 1 46 0.65 10.39 1.7
182 INT14891 Positive_regulation of ACHE 1 10 0.70 5.37 1.64
183 INT223091 Gene_expression of ELF3 1 45 0.62 17.9 1.56
184 INT174689 Gene_expression of Tlr7 1 11 0.67 8.24 1.56
185 INT164152 Negative_regulation of PSMD2 1 9 0.37 3.41 1.56
186 INT43019 Regulation of PHGDH 1 4 0.26 2.46 1.53
187 INT109850 Gene_expression of P2RY4 2 8 0.65 2.05 1.47
188 INT121847 Negative_regulation of BPIFA4P 1 7 0.28 2.46 1.47
189 INT174683 Transcription of Tlr2 2 12 0.58 5.95 1.4
190 INT87029 Positive_regulation of Positive_regulation of IL2 1 8 0.50 8.17 1.36
191 INT160606 Localization of AFP 1 6 0.74 3.39 1.29
192 INT122368 Regulation of Regulation of Ngf 1 1 0.27 1.37 1.27
193 INT8511 Localization of Esr1 1 6 0.80 3.27 1.26
194 INT11137 Negative_regulation of Localization of Ifng 1 3 0.38 2.45 1.26
195 INT46336 Regulation of DNMT3B 1 12 0.53 4.91 1.25
196 INT226444 Negative_regulation of CCL11 1 3 0.41 2.32 1.12
197 INT127459 Negative_regulation of PAH 1 18 0.56 15.15 1.05
198 INT72024 Localization of EDNRA 2 11 0.57 8.22 0.96
199 INT39369 Binding of NARFL 3 14 0.29 16.7 0.93
200 INT192761 Positive_regulation of Gene_expression of SAA1 2 5 0.40 7.45 0.82
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