J:BMC Pregnancy Childbirth

This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT64719	IL1B Positive_regulation of IL6	7	1	0.41	6.84	3.14
2	INT209151	OXT Positive_regulation of PNLIP	1	2	0.08	0.73	0.99
3	INT105435	TNF Positive_regulation of IL6	5	1	0.25	4.45	0.83
4	INT302469	F2 Positive_regulation of Gene_expression of MMP9	1	2	0.01	1.82	0.62
5	INT181471	Binding of Il10 and Ptbp1	1	2	0.05	2.14	0.58
6	INT209152	Regulation of OXT Positive_regulation of PNLIP	1	1	0.05	0.42	0.54
7	INT302466	Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9	1	1	0.01	1.1	0.35
8	INT302467	TIMP1 Positive_regulation of Negative_regulation of COL5A2	1	1	0.00	1.1	0.29
9	INT302468	INCENP Positive_regulation of Gene_expression of MMP9	1	1	0.01	0.72	0.26
10	INT209196	IL1B Positive_regulation of Gene_expression of TRPC3	1	1	0.68	0.23	0.15
11	INT209195	IL1B Regulation of Gene_expression of TRPC3	1	1	0.26	0	0.11
12	INT209155	MMP9 Negative_regulation of TIMP1	1	1	0.01	0.17	0.05
13	INT209157	MMP9 Negative_regulation of MMP2	1	1	0.00	0.16	0.05
14	INT209156	MMP2 Negative_regulation of TIMP1	1	1	0.00	0.17	0.05
15	INT302493	Binding of AGRP and IMPACT	1	1	0.25	0.53	0
16	INT209159	Binding of LHCGR and PDE5A	1	1	0.01	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Reported in Journal	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT6483	Gene_expression of TNF	2	3152	0.78	2515.62	929.82
2	INT9238	Gene_expression of IL6	2	1575	0.78	1135.66	424.22
3	INT467	Gene_expression of POMC	1	1048	0.78	332.8	394.16
4	INT5059	Positive_regulation of TNF	3	1050	0.70	896.51	322.81
5	INT34869	Negative_regulation of PTGS2	1	778	0.59	366.76	319.85
6	INT10832	Gene_expression of IL8	2	1050	0.78	698.72	270
7	INT5972	Gene_expression of IL1B	2	948	0.78	510.91	263.97
8	INT10194	Positive_regulation of IL6	1	702	0.70	600.62	183.38
9	INT425	Localization of PRL	3	455	0.81	189.64	144.8
10	INT9660	Regulation of TNF	1	363	0.62	312.94	139.99
11	INT48895	Gene_expression of Il10	3	333	0.78	221.2	138.52
12	INT50674	Gene_expression of PTGS2	2	459	0.78	253.33	118.51
13	INT915	Positive_regulation of PRL	6	342	0.70	141.96	104.31
14	INT10838	Positive_regulation of IL8	4	381	0.70	295.51	101.62
15	INT11381	Positive_regulation of IL1B	3	330	0.70	209.31	100.9
16	INT71789	Positive_regulation of MAPK1	1	396	0.70	234.44	89.27
17	INT48244	Gene_expression of Il4	1	172	0.76	132.38	73.42
18	INT11380	Negative_regulation of IL1B	1	215	0.59	125.62	72.35
19	INT10837	Positive_regulation of Gene_expression of IL8	1	294	0.70	190.08	70.34
20	INT39153	Positive_regulation of PTGS2	2	182	0.70	96.16	60.6
21	INT1759	Gene_expression of TIMP1	2	267	0.77	133.87	59.29
22	INT73048	Gene_expression of MMP9	3	268	0.77	159.75	57.81
23	INT48232	Gene_expression of MMP1	1	245	0.78	96.31	57.72
24	INT1579	Gene_expression of PRL	3	279	0.78	119.2	55.41
25	INT251	Regulation of INS	1	398	0.62	232.47	55.04
26	INT66383	Phosphorylation of Prkaca	1	143	0.80	30.85	43.38
27	INT29496	Gene_expression of MMP3	1	136	0.75	49.49	41.78
28	INT5454	Localization of CRH	2	124	0.79	79.18	41.53
29	INT918	Positive_regulation of Localization of PRL	2	90	0.70	23.97	40.3
30	INT55135	Positive_regulation of Gene_expression of PTGS2	1	137	0.70	80.32	38.46
31	INT916	Regulation of Localization of PRL	1	92	0.62	22.98	38.13
32	INT11325	Gene_expression of HLA-E	1	209	0.76	98.05	33.72
33	INT7082	Gene_expression of CRH	8	180	0.78	64.66	31.74
34	INT86437	Binding of IL6	1	154	0.48	121.22	29.3
35	INT7035	Regulation of CGA	1	87	0.45	29.04	28.45
36	INT5653	Positive_regulation of ELANE	1	136	0.70	72.78	27.94
37	INT55737	Positive_regulation of MMP2	2	101	0.68	59.11	27.71
38	INT49850	Negative_regulation of PDE4A	6	105	0.58	76.91	26.59
39	INT73047	Positive_regulation of MMP9	4	133	0.68	73.22	26.42
40	INT6441	Positive_regulation of CRH	5	98	0.69	57.22	24.12
41	INT74423	Localization of IL10	1	91	0.80	61.6	22.95
42	INT71047	Gene_expression of CYP19A1	1	122	0.78	68.78	22.21
43	INT5905	Negative_regulation of ELANE	1	113	0.59	47.43	22.09
44	INT955	Gene_expression of GHRH	1	126	0.78	59.91	20.74
45	INT93663	Positive_regulation of MMP1	1	72	0.67	33.38	19.86
46	INT69304	Negative_regulation of Il10	1	47	0.59	36.88	19.79
47	INT74286	Regulation of Il10	1	42	0.44	28.06	19.44
48	INT16445	Gene_expression of IL1A	1	60	0.78	44.46	19.19
49	INT70614	Gene_expression of FAS	5	118	0.75	112.33	19.01
50	INT14724	Negative_regulation of CYP19A1	1	233	0.59	96.56	18.26
51	INT145097	Negative_regulation of Pain1	2	16	0.22	19.11	16.82
52	INT77620	Gene_expression of Fas	1	146	0.78	72.4	16.61
53	INT26314	Positive_regulation of MMP3	1	48	0.67	22.14	16.17
54	INT103245	Positive_regulation of Gene_expression of MMP9	2	64	0.68	36.86	15.7
55	INT75531	Regulation of MAPK1	2	70	0.61	34.39	15.42
56	INT129	Localization of OXTR	1	51	0.80	11.08	15.36
57	INT92823	Positive_regulation of Gene_expression of MMP1	1	65	0.68	25.69	14.31
58	INT80688	Positive_regulation of Positive_regulation of MAPK1	1	72	0.69	39.35	14.11
59	INT16919	Gene_expression of IL36RN	2	48	0.48	32.78	13.83
60	INT11699	Binding of HLA-E	2	85	0.47	52.51	13.41
61	INT27242	Gene_expression of PGR	3	153	0.75	98.77	12.79
62	INT86950	Negative_regulation of Gene_expression of Il10	1	26	0.42	18.92	12.73
63	INT2129	Positive_regulation of F2	2	83	0.70	58.95	12.63
64	INT59080	Negative_regulation of Gene_expression of PTGS2	1	55	0.58	22.92	12.39
65	INT10874	Negative_regulation of Twist1	2	89	0.50	36.84	11.32
66	INT2260	Gene_expression of Tyr	2	30	0.49	7.05	11.31
67	INT86729	Positive_regulation of CDCP1	1	37	0.07	18.74	10.76
68	INT1708	Gene_expression of OXTR	7	56	0.78	6.92	10.69
69	INT126031	Negative_regulation of Gene_expression of MMP9	1	40	0.57	22.71	9.79
70	INT28312	Gene_expression of ABCA1	1	85	0.72	37.69	9.27
71	INT11336	Gene_expression of Ptgfr	1	23	0.78	2.88	9.07
72	INT173587	Protein_catabolism of COL5A2	2	59	0.32	32.73	8.96
73	INT29411	Positive_regulation of ADRB2	1	13	0.65	5.42	8.78
74	INT57057	Gene_expression of APC	1	131	0.78	122.24	8.7
75	INT80034	Positive_regulation of Gene_expression of FAS	1	32	0.67	30.34	8.51
76	INT621	Positive_regulation of SERPINH1	1	19	0.57	21.52	8.44
77	INT26815	Regulation of OXT	3	15	0.46	5.38	8.31
78	INT4487	Positive_regulation of Positive_regulation of PRL	1	27	0.70	8.06	8.09
79	INT6957	Positive_regulation of OXTR	3	38	0.70	6.55	7.81
80	INT79456	Gene_expression of PDE4A	4	35	0.77	19.42	7.42
81	INT103289	Binding of Il10	1	15	0.35	13.67	7.42
82	INT7883	Binding of ADRB2	2	18	0.47	5.49	7.37
83	INT11378	Negative_regulation of Positive_regulation of IL1B	1	23	0.59	10.28	7.26
84	INT67822	Binding of SERPINH1	2	17	0.36	19.05	7.24
85	INT5864	Localization of IL36RN	1	19	0.44	14.5	6.87
86	INT36053	Positive_regulation of Positive_regulation of IL1B	1	22	0.70	11.41	6.84
87	INT173639	Positive_regulation of INCENP	1	40	0.14	20.97	6.7
88	INT100593	Gene_expression of UBAP1	1	8	0.65	13.81	5.74
89	INT57502	Positive_regulation of Gene_expression of CRH	6	30	0.70	23.37	5.7
90	INT1243	Regulation of ADRB2	1	16	0.54	1.84	5.66
91	INT23401	Gene_expression of HLA-DOA	1	91	0.30	38.21	5.52
92	INT15284	Positive_regulation of Lgals3	7	21	0.47	8.88	5.52
93	INT187133	Protein_catabolism of TIMP1	1	19	0.73	11.3	5.51
94	INT174851	Positive_regulation of COL5A2	1	46	0.54	12.73	5.48
95	INT81796	Binding of AGRP	1	62	0.36	37.19	5.3
96	INT10916	Positive_regulation of BDNF-AS	1	39	0.49	25.88	5.28
97	INT127668	Positive_regulation of PDE4A	4	12	0.68	8.39	5.13
98	INT36778	Positive_regulation of Anxty	2	14	0.48	12.85	5.08
99	INT19187	Gene_expression of Lgals3	3	24	0.73	19.72	5.03
100	INT130	Negative_regulation of OXTR	2	19	0.43	4.63	4.96
101	INT1285	Localization of Mmp13	1	12	0.78	8.98	4.93
102	INT21650	Regulation of OXTR	1	29	0.61	5.99	4.91
103	INT130290	Positive_regulation of Localization of IL10	1	16	0.47	9.38	4.75
104	INT102237	Positive_regulation of Gene_expression of MMP3	1	22	0.44	7.77	4.71
105	INT81485	Negative_regulation of IL1RN	1	19	0.57	8.3	4.69
106	INT113517	Binding of Fas	1	16	0.37	15.86	4.62
107	INT14026	Positive_regulation of Igh-6	3	24	0.68	10.84	4.32
108	INT58875	Positive_regulation of FGD1	1	20	0.60	3.88	4.19
109	INT10849	Negative_regulation of OXT	2	14	0.48	2.51	4.19
110	INT4104	Gene_expression of ADRB3	10	19	0.78	2.68	4.12
111	INT19300	Positive_regulation of OXT	1	34	0.43	4.43	4.07
112	INT484	Negative_regulation of ADRB2	2	13	0.59	2.85	3.94
113	INT172677	Gene_expression of SHE	7	65	0.59	25.86	3.85
114	INT109	Binding of ADRB3	5	17	0.47	3.02	3.84
115	INT4012	Negative_regulation of Psd	11	23	0.52	14.12	3.81
116	INT25029	Positive_regulation of Positive_regulation of CRH	2	7	0.49	6.77	3.52
117	INT157342	Gene_expression of S100A9	3	19	0.60	21.27	3.37
118	INT48726	Gene_expression of IGFBP1	2	27	0.67	9.45	3.36
119	INT57252	Negative_regulation of PGR	1	22	0.43	12.95	3.33
120	INT10353	Positive_regulation of PGR	3	34	0.70	21.84	3.28
121	INT15837	Binding of CGA	1	31	0.41	12.06	3.17
122	INT172551	Negative_regulation of INCENP	1	38	0.07	20.83	3.14
123	INT41474	Gene_expression of ADRB2	4	10	0.75	1.56	2.94
124	INT172678	Gene_expression of NUPL2	1	20	0.75	5.06	2.85
125	INT27207	Gene_expression of Psd	2	31	0.73	15.44	2.75
126	INT10854	Gene_expression of OXT	1	13	0.66	3.88	2.74
127	INT98557	Regulation of PDE4A	3	12	0.44	8.42	2.56
128	INT135136	Gene_expression of PEE1	2	6	0.19	3.9	2.53
129	INT188756	Positive_regulation of AGRP	1	43	0.60	23.67	2.51
130	INT16964	Binding of IFNG	1	27	0.48	14.31	2.45
131	INT30857	Binding of OXTR	1	10	0.48	2.27	2.42
132	INT122709	Localization of CYP3A4	1	16	0.75	5.41	2.38
133	INT25666	Negative_regulation of ADRB1	1	11	0.44	3.12	2.33
134	INT64777	Negative_regulation of COL5A2	2	32	0.38	17.4	2.28
135	INT182720	Binding of SHE	2	18	0.26	9.15	2.24
136	INT30372	Regulation of ADRB3	4	8	0.60	0.57	2.24
137	INT34500	Positive_regulation of ADRB3	3	12	0.58	2.59	2.16
138	INT68496	Binding of PGR	2	26	0.48	16.36	2.09
139	INT98132	Regulation of FAS	1	16	0.42	20.57	2.06
140	INT128030	Gene_expression of GJA1	4	23	0.75	7.81	1.88
141	INT124322	Negative_regulation of PNLIP	2	11	0.31	6.53	1.88
142	INT5021	Regulation of Lgals3	1	7	0.58	2.08	1.86
143	INT47535	Positive_regulation of Gene_expression of Ptgfr	1	6	0.61	0.25	1.73
144	INT107948	Gene_expression of Spl	1	4	0.37	3.94	1.67
145	INT954	Positive_regulation of Gene_expression of GHRH	1	18	0.50	7.6	1.63
146	INT12062	Positive_regulation of Gene_expression of OXTR	2	9	0.69	1.04	1.63
147	INT36188	Positive_regulation of PNLIP	1	7	0.68	5.99	1.6
148	INT91739	Positive_regulation of MYLK	1	9	0.54	2.89	1.58
149	INT43482	Regulation of Binding of ADRB3	2	4	0.60	1.06	1.54
150	INT5319	Positive_regulation of PTGFR	1	9	0.32	4.96	1.44
151	INT213750	Positive_regulation of NHS	1	14	0.59	2.17	1.43
152	INT148221	Gene_expression of CXCL14	1	5	0.74	2.91	1.34
153	INT130773	Regulation of Gene_expression of FAS	3	5	0.37	6.87	1.32
154	INT209962	Binding of RDBP	1	4	0.11	2.93	1.27
155	INT287308	Negative_regulation of ENO1	2	5	0.59	4.07	1.24
156	INT115108	Negative_regulation of Gene_expression of FAS	1	9	0.57	9.16	1.23
157	INT209138	Negative_regulation of Negative_regulation of PDE4A	1	4	0.42	3.84	1.21
158	INT48554	Positive_regulation of SP1	1	12	0.49	3.64	1.2
159	INT18788	Regulation of ANC	1	6	0.60	0.15	1.12
160	INT79454	Gene_expression of PDE4B	1	12	0.77	1.72	1.11
161	INT139117	Negative_regulation of Gene_expression of PDE4A	1	4	0.42	2.28	1.02
162	INT71031	Gene_expression of ADRB1	1	5	0.55	2.96	1.01
163	INT30316	Regulation of CHAT	1	6	0.43	1.95	0.96
164	INT209144	Positive_regulation of PDE4B	3	4	0.45	2.03	0.95
165	INT94546	Transcription of Fas	1	13	0.56	6.99	0.88
166	INT171406	Gene_expression of Pklr	1	3	0.65	2.75	0.86
167	INT39864	Regulation of PNLIP	1	2	0.10	0.74	0.85
168	INT1852	Localization of ADRB3	2	3	0.75	1.02	0.79
169	INT178116	Phosphorylation of GJA1	3	7	0.80	4.09	0.74
170	INT276424	Negative_regulation of IMPACT	1	4	0.32	2.6	0.72
171	INT157892	Binding of PNLIP	1	5	0.25	4.58	0.65
172	INT171407	Gene_expression of Vencon1	1	2	0.19	2.19	0.62
173	INT188754	Localization of AGRP	3	15	0.74	8.88	0.6
174	INT144080	Gene_expression of LDB3	2	17	0.04	1.33	0.58
175	INT79797	Positive_regulation of TRPC3	1	4	0.38	0.12	0.58
176	INT18644	Binding of OXT	1	6	0.31	1.22	0.55
177	INT209198	Gene_expression of TRPC3	4	5	0.72	0.52	0.53
178	INT209154	Negative_regulation of Positive_regulation of PNLIP	1	1	0.15	0.5	0.5
179	INT209153	Negative_regulation of Positive_regulation of OXT	1	1	0.18	0.5	0.5
180	INT209136	Regulation of Gene_expression of PDE4A	1	3	0.27	1.63	0.49
181	INT133332	Regulation of Positive_regulation of Lgals3	1	3	0.42	0.61	0.45
182	INT192937	Positive_regulation of Gene_expression of GJA1	2	4	0.67	0.4	0.44
183	INT209189	Binding of AVPR1A	1	5	0.29	1.94	0.43
184	INT79450	Positive_regulation of Gene_expression of PDE4B	1	6	0.50	0.6	0.41
185	INT185370	Gene_expression of ANC	1	28	0.65	13.28	0.4
186	INT15762	Negative_regulation of asp1	1	6	0.37	0.71	0.4
187	INT202189	Transcription of PGR	3	5	0.51	0.8	0.4
188	INT209180	Transcription of ABCA1	1	4	0.47	1.09	0.39
189	INT8126	Localization of Fut4	1	3	0.60	1.82	0.38
190	INT209145	Negative_regulation of Gene_expression of ADRB3	1	2	0.43	0.76	0.38
191	INT209137	Negative_regulation of Positive_regulation of PDE4A	1	1	0.42	0.8	0.37
192	INT197147	Gene_expression of TCFL5	1	2	0.07	0	0.35
193	INT61611	Positive_regulation of ANC	6	17	0.41	4.43	0.31
194	INT181468	Positive_regulation of Ptbp1	1	1	0.06	1.05	0.3
195	INT146524	Negative_regulation of AADAC	1	5	0.04	4.2	0.28
196	INT209140	Transcription of PDE4A	2	3	0.71	0.59	0.26
197	INT209197	Positive_regulation of Gene_expression of TRPC3	2	1	0.64	0.29	0.26
198	INT244368	Binding of CENPI	1	1	0.04	0.65	0.25
199	INT132951	Regulation of GJA1	2	2	0.57	0.79	0.24
200	INT168469	Localization of Lgals3	1	5	0.28	2.46	0.23