J:BMC Pregnancy Childbirth

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT64719 IL1B Positive_regulation of IL6 7 1 0.41 6.84 3.14
2 INT209151 OXT Positive_regulation of PNLIP 1 2 0.08 0.73 0.99
3 INT105435 TNF Positive_regulation of IL6 5 1 0.25 4.45 0.83
4 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 2 0.01 1.82 0.62
5 INT181471 Binding of Il10 and Ptbp1 1 2 0.05 2.14 0.58
6 INT209152 Regulation of OXT Positive_regulation of PNLIP 1 1 0.05 0.42 0.54
7 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 1 0.01 1.1 0.35
8 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 1 0.00 1.1 0.29
9 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 1 0.01 0.72 0.26
10 INT209196 IL1B Positive_regulation of Gene_expression of TRPC3 1 1 0.68 0.23 0.15
11 INT209195 IL1B Regulation of Gene_expression of TRPC3 1 1 0.26 0 0.11
12 INT209155 MMP9 Negative_regulation of TIMP1 1 1 0.01 0.17 0.05
13 INT209157 MMP9 Negative_regulation of MMP2 1 1 0.00 0.16 0.05
14 INT209156 MMP2 Negative_regulation of TIMP1 1 1 0.00 0.17 0.05
15 INT302493 Binding of AGRP and IMPACT 1 1 0.25 0.53 0
16 INT209159 Binding of LHCGR and PDE5A 1 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT6483 Gene_expression of TNF 2 3152 0.78 2515.62 929.82
2 INT9238 Gene_expression of IL6 2 1575 0.78 1135.66 424.22
3 INT467 Gene_expression of POMC 1 1048 0.78 332.8 394.16
4 INT5059 Positive_regulation of TNF 3 1050 0.70 896.51 322.81
5 INT34869 Negative_regulation of PTGS2 1 778 0.59 366.76 319.85
6 INT10832 Gene_expression of IL8 2 1050 0.78 698.72 270
7 INT5972 Gene_expression of IL1B 2 948 0.78 510.91 263.97
8 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
9 INT425 Localization of PRL 3 455 0.81 189.64 144.8
10 INT9660 Regulation of TNF 1 363 0.62 312.94 139.99
11 INT48895 Gene_expression of Il10 3 333 0.78 221.2 138.52
12 INT50674 Gene_expression of PTGS2 2 459 0.78 253.33 118.51
13 INT915 Positive_regulation of PRL 6 342 0.70 141.96 104.31
14 INT10838 Positive_regulation of IL8 4 381 0.70 295.51 101.62
15 INT11381 Positive_regulation of IL1B 3 330 0.70 209.31 100.9
16 INT71789 Positive_regulation of MAPK1 1 396 0.70 234.44 89.27
17 INT48244 Gene_expression of Il4 1 172 0.76 132.38 73.42
18 INT11380 Negative_regulation of IL1B 1 215 0.59 125.62 72.35
19 INT10837 Positive_regulation of Gene_expression of IL8 1 294 0.70 190.08 70.34
20 INT39153 Positive_regulation of PTGS2 2 182 0.70 96.16 60.6
21 INT1759 Gene_expression of TIMP1 2 267 0.77 133.87 59.29
22 INT73048 Gene_expression of MMP9 3 268 0.77 159.75 57.81
23 INT48232 Gene_expression of MMP1 1 245 0.78 96.31 57.72
24 INT1579 Gene_expression of PRL 3 279 0.78 119.2 55.41
25 INT251 Regulation of INS 1 398 0.62 232.47 55.04
26 INT66383 Phosphorylation of Prkaca 1 143 0.80 30.85 43.38
27 INT29496 Gene_expression of MMP3 1 136 0.75 49.49 41.78
28 INT5454 Localization of CRH 2 124 0.79 79.18 41.53
29 INT918 Positive_regulation of Localization of PRL 2 90 0.70 23.97 40.3
30 INT55135 Positive_regulation of Gene_expression of PTGS2 1 137 0.70 80.32 38.46
31 INT916 Regulation of Localization of PRL 1 92 0.62 22.98 38.13
32 INT11325 Gene_expression of HLA-E 1 209 0.76 98.05 33.72
33 INT7082 Gene_expression of CRH 8 180 0.78 64.66 31.74
34 INT86437 Binding of IL6 1 154 0.48 121.22 29.3
35 INT7035 Regulation of CGA 1 87 0.45 29.04 28.45
36 INT5653 Positive_regulation of ELANE 1 136 0.70 72.78 27.94
37 INT55737 Positive_regulation of MMP2 2 101 0.68 59.11 27.71
38 INT49850 Negative_regulation of PDE4A 6 105 0.58 76.91 26.59
39 INT73047 Positive_regulation of MMP9 4 133 0.68 73.22 26.42
40 INT6441 Positive_regulation of CRH 5 98 0.69 57.22 24.12
41 INT74423 Localization of IL10 1 91 0.80 61.6 22.95
42 INT71047 Gene_expression of CYP19A1 1 122 0.78 68.78 22.21
43 INT5905 Negative_regulation of ELANE 1 113 0.59 47.43 22.09
44 INT955 Gene_expression of GHRH 1 126 0.78 59.91 20.74
45 INT93663 Positive_regulation of MMP1 1 72 0.67 33.38 19.86
46 INT69304 Negative_regulation of Il10 1 47 0.59 36.88 19.79
47 INT74286 Regulation of Il10 1 42 0.44 28.06 19.44
48 INT16445 Gene_expression of IL1A 1 60 0.78 44.46 19.19
49 INT70614 Gene_expression of FAS 5 118 0.75 112.33 19.01
50 INT14724 Negative_regulation of CYP19A1 1 233 0.59 96.56 18.26
51 INT145097 Negative_regulation of Pain1 2 16 0.22 19.11 16.82
52 INT77620 Gene_expression of Fas 1 146 0.78 72.4 16.61
53 INT26314 Positive_regulation of MMP3 1 48 0.67 22.14 16.17
54 INT103245 Positive_regulation of Gene_expression of MMP9 2 64 0.68 36.86 15.7
55 INT75531 Regulation of MAPK1 2 70 0.61 34.39 15.42
56 INT129 Localization of OXTR 1 51 0.80 11.08 15.36
57 INT92823 Positive_regulation of Gene_expression of MMP1 1 65 0.68 25.69 14.31
58 INT80688 Positive_regulation of Positive_regulation of MAPK1 1 72 0.69 39.35 14.11
59 INT16919 Gene_expression of IL36RN 2 48 0.48 32.78 13.83
60 INT11699 Binding of HLA-E 2 85 0.47 52.51 13.41
61 INT27242 Gene_expression of PGR 3 153 0.75 98.77 12.79
62 INT86950 Negative_regulation of Gene_expression of Il10 1 26 0.42 18.92 12.73
63 INT2129 Positive_regulation of F2 2 83 0.70 58.95 12.63
64 INT59080 Negative_regulation of Gene_expression of PTGS2 1 55 0.58 22.92 12.39
65 INT10874 Negative_regulation of Twist1 2 89 0.50 36.84 11.32
66 INT2260 Gene_expression of Tyr 2 30 0.49 7.05 11.31
67 INT86729 Positive_regulation of CDCP1 1 37 0.07 18.74 10.76
68 INT1708 Gene_expression of OXTR 7 56 0.78 6.92 10.69
69 INT126031 Negative_regulation of Gene_expression of MMP9 1 40 0.57 22.71 9.79
70 INT28312 Gene_expression of ABCA1 1 85 0.72 37.69 9.27
71 INT11336 Gene_expression of Ptgfr 1 23 0.78 2.88 9.07
72 INT173587 Protein_catabolism of COL5A2 2 59 0.32 32.73 8.96
73 INT29411 Positive_regulation of ADRB2 1 13 0.65 5.42 8.78
74 INT57057 Gene_expression of APC 1 131 0.78 122.24 8.7
75 INT80034 Positive_regulation of Gene_expression of FAS 1 32 0.67 30.34 8.51
76 INT621 Positive_regulation of SERPINH1 1 19 0.57 21.52 8.44
77 INT26815 Regulation of OXT 3 15 0.46 5.38 8.31
78 INT4487 Positive_regulation of Positive_regulation of PRL 1 27 0.70 8.06 8.09
79 INT6957 Positive_regulation of OXTR 3 38 0.70 6.55 7.81
80 INT79456 Gene_expression of PDE4A 4 35 0.77 19.42 7.42
81 INT103289 Binding of Il10 1 15 0.35 13.67 7.42
82 INT7883 Binding of ADRB2 2 18 0.47 5.49 7.37
83 INT11378 Negative_regulation of Positive_regulation of IL1B 1 23 0.59 10.28 7.26
84 INT67822 Binding of SERPINH1 2 17 0.36 19.05 7.24
85 INT5864 Localization of IL36RN 1 19 0.44 14.5 6.87
86 INT36053 Positive_regulation of Positive_regulation of IL1B 1 22 0.70 11.41 6.84
87 INT173639 Positive_regulation of INCENP 1 40 0.14 20.97 6.7
88 INT100593 Gene_expression of UBAP1 1 8 0.65 13.81 5.74
89 INT57502 Positive_regulation of Gene_expression of CRH 6 30 0.70 23.37 5.7
90 INT1243 Regulation of ADRB2 1 16 0.54 1.84 5.66
91 INT23401 Gene_expression of HLA-DOA 1 91 0.30 38.21 5.52
92 INT15284 Positive_regulation of Lgals3 7 21 0.47 8.88 5.52
93 INT187133 Protein_catabolism of TIMP1 1 19 0.73 11.3 5.51
94 INT174851 Positive_regulation of COL5A2 1 46 0.54 12.73 5.48
95 INT81796 Binding of AGRP 1 62 0.36 37.19 5.3
96 INT10916 Positive_regulation of BDNF-AS 1 39 0.49 25.88 5.28
97 INT127668 Positive_regulation of PDE4A 4 12 0.68 8.39 5.13
98 INT36778 Positive_regulation of Anxty 2 14 0.48 12.85 5.08
99 INT19187 Gene_expression of Lgals3 3 24 0.73 19.72 5.03
100 INT130 Negative_regulation of OXTR 2 19 0.43 4.63 4.96
101 INT1285 Localization of Mmp13 1 12 0.78 8.98 4.93
102 INT21650 Regulation of OXTR 1 29 0.61 5.99 4.91
103 INT130290 Positive_regulation of Localization of IL10 1 16 0.47 9.38 4.75
104 INT102237 Positive_regulation of Gene_expression of MMP3 1 22 0.44 7.77 4.71
105 INT81485 Negative_regulation of IL1RN 1 19 0.57 8.3 4.69
106 INT113517 Binding of Fas 1 16 0.37 15.86 4.62
107 INT14026 Positive_regulation of Igh-6 3 24 0.68 10.84 4.32
108 INT58875 Positive_regulation of FGD1 1 20 0.60 3.88 4.19
109 INT10849 Negative_regulation of OXT 2 14 0.48 2.51 4.19
110 INT4104 Gene_expression of ADRB3 10 19 0.78 2.68 4.12
111 INT19300 Positive_regulation of OXT 1 34 0.43 4.43 4.07
112 INT484 Negative_regulation of ADRB2 2 13 0.59 2.85 3.94
113 INT172677 Gene_expression of SHE 7 65 0.59 25.86 3.85
114 INT109 Binding of ADRB3 5 17 0.47 3.02 3.84
115 INT4012 Negative_regulation of Psd 11 23 0.52 14.12 3.81
116 INT25029 Positive_regulation of Positive_regulation of CRH 2 7 0.49 6.77 3.52
117 INT157342 Gene_expression of S100A9 3 19 0.60 21.27 3.37
118 INT48726 Gene_expression of IGFBP1 2 27 0.67 9.45 3.36
119 INT57252 Negative_regulation of PGR 1 22 0.43 12.95 3.33
120 INT10353 Positive_regulation of PGR 3 34 0.70 21.84 3.28
121 INT15837 Binding of CGA 1 31 0.41 12.06 3.17
122 INT172551 Negative_regulation of INCENP 1 38 0.07 20.83 3.14
123 INT41474 Gene_expression of ADRB2 4 10 0.75 1.56 2.94
124 INT172678 Gene_expression of NUPL2 1 20 0.75 5.06 2.85
125 INT27207 Gene_expression of Psd 2 31 0.73 15.44 2.75
126 INT10854 Gene_expression of OXT 1 13 0.66 3.88 2.74
127 INT98557 Regulation of PDE4A 3 12 0.44 8.42 2.56
128 INT135136 Gene_expression of PEE1 2 6 0.19 3.9 2.53
129 INT188756 Positive_regulation of AGRP 1 43 0.60 23.67 2.51
130 INT16964 Binding of IFNG 1 27 0.48 14.31 2.45
131 INT30857 Binding of OXTR 1 10 0.48 2.27 2.42
132 INT122709 Localization of CYP3A4 1 16 0.75 5.41 2.38
133 INT25666 Negative_regulation of ADRB1 1 11 0.44 3.12 2.33
134 INT64777 Negative_regulation of COL5A2 2 32 0.38 17.4 2.28
135 INT182720 Binding of SHE 2 18 0.26 9.15 2.24
136 INT30372 Regulation of ADRB3 4 8 0.60 0.57 2.24
137 INT34500 Positive_regulation of ADRB3 3 12 0.58 2.59 2.16
138 INT68496 Binding of PGR 2 26 0.48 16.36 2.09
139 INT98132 Regulation of FAS 1 16 0.42 20.57 2.06
140 INT128030 Gene_expression of GJA1 4 23 0.75 7.81 1.88
141 INT124322 Negative_regulation of PNLIP 2 11 0.31 6.53 1.88
142 INT5021 Regulation of Lgals3 1 7 0.58 2.08 1.86
143 INT47535 Positive_regulation of Gene_expression of Ptgfr 1 6 0.61 0.25 1.73
144 INT107948 Gene_expression of Spl 1 4 0.37 3.94 1.67
145 INT954 Positive_regulation of Gene_expression of GHRH 1 18 0.50 7.6 1.63
146 INT12062 Positive_regulation of Gene_expression of OXTR 2 9 0.69 1.04 1.63
147 INT36188 Positive_regulation of PNLIP 1 7 0.68 5.99 1.6
148 INT91739 Positive_regulation of MYLK 1 9 0.54 2.89 1.58
149 INT43482 Regulation of Binding of ADRB3 2 4 0.60 1.06 1.54
150 INT5319 Positive_regulation of PTGFR 1 9 0.32 4.96 1.44
151 INT213750 Positive_regulation of NHS 1 14 0.59 2.17 1.43
152 INT148221 Gene_expression of CXCL14 1 5 0.74 2.91 1.34
153 INT130773 Regulation of Gene_expression of FAS 3 5 0.37 6.87 1.32
154 INT209962 Binding of RDBP 1 4 0.11 2.93 1.27
155 INT287308 Negative_regulation of ENO1 2 5 0.59 4.07 1.24
156 INT115108 Negative_regulation of Gene_expression of FAS 1 9 0.57 9.16 1.23
157 INT209138 Negative_regulation of Negative_regulation of PDE4A 1 4 0.42 3.84 1.21
158 INT48554 Positive_regulation of SP1 1 12 0.49 3.64 1.2
159 INT18788 Regulation of ANC 1 6 0.60 0.15 1.12
160 INT79454 Gene_expression of PDE4B 1 12 0.77 1.72 1.11
161 INT139117 Negative_regulation of Gene_expression of PDE4A 1 4 0.42 2.28 1.02
162 INT71031 Gene_expression of ADRB1 1 5 0.55 2.96 1.01
163 INT30316 Regulation of CHAT 1 6 0.43 1.95 0.96
164 INT209144 Positive_regulation of PDE4B 3 4 0.45 2.03 0.95
165 INT94546 Transcription of Fas 1 13 0.56 6.99 0.88
166 INT171406 Gene_expression of Pklr 1 3 0.65 2.75 0.86
167 INT39864 Regulation of PNLIP 1 2 0.10 0.74 0.85
168 INT1852 Localization of ADRB3 2 3 0.75 1.02 0.79
169 INT178116 Phosphorylation of GJA1 3 7 0.80 4.09 0.74
170 INT276424 Negative_regulation of IMPACT 1 4 0.32 2.6 0.72
171 INT157892 Binding of PNLIP 1 5 0.25 4.58 0.65
172 INT171407 Gene_expression of Vencon1 1 2 0.19 2.19 0.62
173 INT188754 Localization of AGRP 3 15 0.74 8.88 0.6
174 INT144080 Gene_expression of LDB3 2 17 0.04 1.33 0.58
175 INT79797 Positive_regulation of TRPC3 1 4 0.38 0.12 0.58
176 INT18644 Binding of OXT 1 6 0.31 1.22 0.55
177 INT209198 Gene_expression of TRPC3 4 5 0.72 0.52 0.53
178 INT209154 Negative_regulation of Positive_regulation of PNLIP 1 1 0.15 0.5 0.5
179 INT209153 Negative_regulation of Positive_regulation of OXT 1 1 0.18 0.5 0.5
180 INT209136 Regulation of Gene_expression of PDE4A 1 3 0.27 1.63 0.49
181 INT133332 Regulation of Positive_regulation of Lgals3 1 3 0.42 0.61 0.45
182 INT192937 Positive_regulation of Gene_expression of GJA1 2 4 0.67 0.4 0.44
183 INT209189 Binding of AVPR1A 1 5 0.29 1.94 0.43
184 INT79450 Positive_regulation of Gene_expression of PDE4B 1 6 0.50 0.6 0.41
185 INT185370 Gene_expression of ANC 1 28 0.65 13.28 0.4
186 INT15762 Negative_regulation of asp1 1 6 0.37 0.71 0.4
187 INT202189 Transcription of PGR 3 5 0.51 0.8 0.4
188 INT209180 Transcription of ABCA1 1 4 0.47 1.09 0.39
189 INT8126 Localization of Fut4 1 3 0.60 1.82 0.38
190 INT209145 Negative_regulation of Gene_expression of ADRB3 1 2 0.43 0.76 0.38
191 INT209137 Negative_regulation of Positive_regulation of PDE4A 1 1 0.42 0.8 0.37
192 INT197147 Gene_expression of TCFL5 1 2 0.07 0 0.35
193 INT61611 Positive_regulation of ANC 6 17 0.41 4.43 0.31
194 INT181468 Positive_regulation of Ptbp1 1 1 0.06 1.05 0.3
195 INT146524 Negative_regulation of AADAC 1 5 0.04 4.2 0.28
196 INT209140 Transcription of PDE4A 2 3 0.71 0.59 0.26
197 INT209197 Positive_regulation of Gene_expression of TRPC3 2 1 0.64 0.29 0.26
198 INT244368 Binding of CENPI 1 1 0.04 0.65 0.25
199 INT132951 Regulation of GJA1 2 2 0.57 0.79 0.24
200 INT168469 Localization of Lgals3 1 5 0.28 2.46 0.23
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