J:BMC Res Notes

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This page displays the top molecular interactions and top single events that were mentioned in the literature in this journal. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT326509 Binding of ACE and VWF 1 2 0.05 2.07 1.59
2 INT301166 LRP2 Regulation of TRD@ 1 2 0.12 1.93 1.21
3 INT352295 Binding of P2RY2 and Agtr1a 1 6 0.01 0.08 1.02
4 INT290671 Binding of Socs3 and Stat3 2 1 0.23 1.59 0.45
5 INT346527 Binding of PTH2R and TFIP11 1 8 0.18 0.11 0.42
6 INT326514 Sugt1 Negative_regulation of MTHFR 1 1 0.01 0.77 0.42
7 INT83749 Gnrhr Positive_regulation of Gene_expression of Fos 2 1 0.21 0.14 0.39
8 INT312803 F2 Positive_regulation of NPEPPS 1 1 0.01 1.32 0.32
9 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 1 0.01 1.33 0.32
10 INT315200 Negative_regulation of Binding of Socs3 and Stat3 1 1 0.26 1.18 0.27
11 INT304582 IL12A Positive_regulation of Gene_expression of TH1L 1 2 0.21 0.83 0.25
12 INT304580 IL12A Regulation of Gene_expression of TH1L 1 2 0.19 0.82 0.25
13 INT346519 Binding of PTHLH and TFIP11 1 1 0.09 0.12 0.17
14 INT352290 Binding of Agtr1a and P2ry1 1 1 0.00 0 0.16
15 INT346530 Binding of PTH1R and TFIP11 1 1 0.15 0 0.11
16 INT346526 Binding of ADORA1 and PTH1R 1 2 0.01 0 0.1
17 INT309780 Binding of PTH and PTH1R 3 3 0.12 0.3 0.09
18 INT304581 IL4 Positive_regulation of Gene_expression of IGHE 1 1 0.17 0.35 0.09
19 INT346529 Binding of PTH1R and TACR1 1 1 0.00 0 0.05
20 INT346523 Binding of PTH1R and RHO 1 1 0.01 0 0.05
21 INT346528 Binding of PTH2R and DLEU2 1 1 0.09 0 0.04
22 INT346518 TFIP11 Regulation of PTH2R 1 1 0.23 0 0.04
23 INT346522 Binding of MCL1 and PTH 1 1 0.00 0 0
24 INT346525 Binding of PTH and PTH2R 1 1 0.11 0 0
25 INT346520 Binding of TPM3 and TFIP11 1 1 0.06 0 0
26 INT346524 Binding of PTHLH and PTH2R 1 1 0.10 0 0
27 INT346521 Binding of PTH and TFIP11 1 1 0.10 0 0
28 INT304944 Positive_regulation of Binding of Tnp1 and Ca2 1 1 0.04 0.33 0
29 INT308030 Binding of Mpz and ASPM 1 1 0.02 0.55 0
30 INT308029 ASPM Positive_regulation of Regulation of Mpz 1 1 0.02 0.55 0
31 INT248387 CHD5 Regulation of Gene_expression of TP53 1 1 0.20 0.83 0
32 INT304945 Binding of Tnp1 and Ca2 1 3 0.03 0.97 0

Single Events

The table below shows the top 100 pain related interactions that have been reported in this journal. They are ordered first by their pain relevance and then by number of times they were reported in this journal. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Reported in Journal Documents TM Confidence Disease Relevance Pain Relevance
1 INT5200 Gene_expression of Fos 12 3083 0.78 894.43 1639.02
2 INT6483 Gene_expression of TNF 3 3152 0.78 2515.62 929.82
3 INT5202 Positive_regulation of Gene_expression of Fos 8 1163 0.70 319.28 684
4 INT5228 Positive_regulation of Fos 8 934 0.70 209.8 503.87
5 INT9238 Gene_expression of IL6 4 1575 0.78 1135.66 424.22
6 INT63932 Positive_regulation of Ephb1 3 537 0.70 259.67 296.14
7 INT5591 Regulation of Gene_expression of Fos 3 425 0.62 129.06 265.78
8 INT156 Negative_regulation of Prl 2 542 0.59 131.97 192.24
9 INT10194 Positive_regulation of IL6 1 702 0.70 600.62 183.38
10 INT1033 Positive_regulation of Ca2 5 507 0.68 131.76 147.64
11 INT60694 Gene_expression of Il10 2 567 0.78 369.48 143.69
12 INT8243 Positive_regulation of Il6 3 451 0.70 358.24 119.28
13 INT48923 Gene_expression of Ephb1 2 211 0.77 106.23 109.9
14 INT11051 Positive_regulation of Gene_expression of IL6 1 415 0.69 319.21 109.3
15 INT5587 Regulation of Fos 1 191 0.62 40.81 99.7
16 INT4822 Localization of Ca2 3 417 0.80 99.57 96.45
17 INT94953 Negative_regulation of Mapk14 1 156 0.59 104.77 91.51
18 INT71789 Positive_regulation of MAPK1 1 396 0.70 234.44 89.27
19 INT99070 Gene_expression of Mapk14 1 147 0.78 103.99 79.59
20 INT60691 Gene_expression of Il12a 23 331 0.78 208.03 75.96
21 INT1497 Negative_regulation of Gh 1 415 0.59 192.95 74.71
22 INT9236 Regulation of Gene_expression of TNF 1 204 0.62 162.66 72.99
23 INT56298 Gene_expression of IL4 1 306 0.78 182.18 72.92
24 INT170332 Gene_expression of IFN1@ 10 477 0.75 275.21 69.65
25 INT5861 Gene_expression of Egr1 11 203 0.78 49.35 68.13
26 INT3375 Gene_expression of IGHE 3 535 0.77 387.47 65.46
27 INT13286 Gene_expression of Ca2 2 317 0.67 71.58 65.01
28 INT1032 Regulation of Ca2 2 202 0.52 54.91 53.03
29 INT48920 Negative_regulation of Ephb1 1 107 0.57 43.6 51.02
30 INT9210 Regulation of IL6 1 166 0.62 125.61 49.95
31 INT374 Positive_regulation of Ldha 1 212 0.70 107.08 47.43
32 INT4004 Gene_expression of IGHG3 4 321 0.71 221.03 42.33
33 INT13354 Transcription of TNF 1 108 0.72 85.81 42.32
34 INT48929 Regulation of Ephb1 1 71 0.62 24.42 42.11
35 INT61619 Gene_expression of IL12A 9 194 0.77 146.07 41.97
36 INT3987 Positive_regulation of IGHE 1 316 0.70 283.2 40.16
37 INT3758 Gene_expression of ALB 1 326 0.78 184.65 38.75
38 INT9239 Regulation of Gene_expression of IL6 1 106 0.61 75.24 36.53
39 INT12029 Gene_expression of Car1 1 143 0.67 29.69 36.39
40 INT70437 Negative_regulation of Mdk 1 115 0.57 41.03 35.72
41 INT1361 Negative_regulation of Gnrhr 1 118 0.58 57.77 35.54
42 INT72651 Gene_expression of TH1L 5 114 0.75 80.15 35.15
43 INT5862 Positive_regulation of Egr1 4 82 0.70 30.4 33.96
44 INT63933 Negative_regulation of Positive_regulation of Ephb1 1 53 0.58 22.83 33.43
45 INT6053 Transcription of Fos 17 107 0.72 20.97 31.88
46 INT34729 Positive_regulation of IFN1@ 2 233 0.67 128.04 30.38
47 INT86437 Binding of IL6 2 154 0.48 121.22 29.3
48 INT28361 Gene_expression of TP53 3 443 0.78 384.86 28.8
49 INT69157 Gene_expression of IL5 2 127 0.77 102.58 26.81
50 INT16428 Positive_regulation of Gtf3a 1 135 0.20 106.44 26.67
51 INT6054 Positive_regulation of Gene_expression of Egr1 2 67 0.70 18.45 25.93
52 INT19330 Binding of HLA-A 2 99 0.48 76.26 22.85
53 INT7678 Localization of Alb 1 142 0.81 80.93 22.49
54 INT11161 Gene_expression of HLA-DRB1 1 121 0.78 75.33 20.96
55 INT86751 Negative_regulation of Il10 1 62 0.59 40.1 20.51
56 INT88949 Positive_regulation of Il12a 2 79 0.60 47.68 19.98
57 INT192409 Positive_regulation of Gene_expression of IFN1@ 4 102 0.67 64.66 18.8
58 INT93948 Negative_regulation of Gene_expression of Il12a 2 48 0.55 27.77 16.87
59 INT18660 Binding of Gnrhr 1 45 0.41 10.6 16.85
60 INT170754 Localization of IFN1@ 1 121 0.78 66.78 15.6
61 INT142464 Gene_expression of Socs3 14 58 0.77 52.04 15.34
62 INT75540 Positive_regulation of TH1L 2 62 0.67 43.45 15.02
63 INT129584 Positive_regulation of Stat3 2 97 0.68 87.07 14.86
64 INT79703 Gene_expression of Agtr1a 12 46 0.76 14.18 13.77
65 INT78472 Gene_expression of CDKN2A 4 223 0.78 173.76 13.61
66 INT20066 Gene_expression of Mdk 1 38 0.76 21.41 13.4
67 INT61624 Positive_regulation of Gene_expression of IL12A 4 50 0.56 33.07 13.07
68 INT54763 Binding of Il6 2 82 0.48 63.27 12.89
69 INT2129 Positive_regulation of F2 1 83 0.70 58.95 12.63
70 INT30101 Regulation of Cacna1a 1 25 0.45 14.38 12.43
71 INT10433 Positive_regulation of Junb 1 35 0.70 6.55 12.42
72 INT9483 Gene_expression of Junb 2 34 0.78 3.24 12.08
73 INT69158 Localization of IL4 1 48 0.71 31.3 11.98
74 INT4047 Binding of F13A1 2 105 0.43 66.54 11.81
75 INT744 Positive_regulation of PTH 5 130 0.70 95.02 11.7
76 INT53038 Positive_regulation of Agtr1a 2 35 0.67 23.76 11.68
77 INT102272 Regulation of TH1L 1 41 0.44 30.89 11.63
78 INT6051 Positive_regulation of Transcription of Fos 6 27 0.69 6.3 11.48
79 INT94545 Positive_regulation of C7orf49 1 37 0.69 12.91 11.19
80 INT82854 Gene_expression of MRGPRX1 2 61 0.75 10.14 10.65
81 INT33094 Regulation of Localization of Ca2 1 28 0.38 8.65 9.96
82 INT32239 Gene_expression of Car3 1 38 0.67 6.86 9.76
83 INT105816 Gene_expression of P2RY2 12 53 0.78 16.47 9.67
84 INT3988 Positive_regulation of Gene_expression of IGHE 1 98 0.68 91.46 9.61
85 INT33220 Negative_regulation of ras 1 110 0.58 70.21 9.19
86 INT621 Positive_regulation of SERPINH1 1 19 0.57 21.52 8.44
87 INT142462 Positive_regulation of Gene_expression of Socs3 2 23 0.68 23.27 8.27
88 INT70572 Gene_expression of Fst 1 33 0.78 5.22 8.24
89 INT61628 Negative_regulation of Gene_expression of IL4 1 31 0.55 20.96 8.18
90 INT60034 Positive_regulation of VWF 1 40 0.68 30.42 8.15
91 INT6957 Positive_regulation of OXTR 1 38 0.70 6.55 7.81
92 INT6055 Transcription of Egr1 21 47 0.69 3.61 7.68
93 INT49490 Positive_regulation of Transcription of TNF 1 19 0.70 14.76 7.58
94 INT9478 Positive_regulation of Gene_expression of Junb 1 19 0.70 2.34 7.41
95 INT76253 Positive_regulation of P2RY2 2 29 0.70 13.99 7.33
96 INT67822 Binding of SERPINH1 1 17 0.36 19.05 7.24
97 INT1124 Negative_regulation of CD40LG 1 53 0.57 36.26 7
98 INT132822 Localization of IL13 1 26 0.67 22.85 6.66
99 INT138833 Binding of MTHFR 4 12 0.46 16.08 6.4
100 INT5860 Regulation of Gene_expression of Egr1 3 20 0.62 3.02 6.38
101 INT86060 Positive_regulation of Fst 1 13 0.64 3.04 6.33
102 INT233812 Gene_expression of PTH1R 1 32 0.77 18.15 6.15
103 INT1493 Positive_regulation of Prkacb 1 8 0.59 2.75 5.99
104 INT67060 Negative_regulation of Transcription of TNF 1 17 0.59 12.94 5.88
105 INT69153 Positive_regulation of Gene_expression of IL5 1 22 0.32 23.59 5.7
106 INT102836 Binding of LRP2 2 12 0.38 11.27 5.58
107 INT125467 Positive_regulation of Gene_expression of CDKN2A 2 35 0.63 39.07 5.56
108 INT69156 Localization of IL5 1 21 0.68 14.95 5.37
109 INT86219 Negative_regulation of GSTK1 1 25 0.41 8.99 4.97
110 INT51944 Positive_regulation of Transcription of Egr1 3 12 0.49 1.96 4.72
111 INT62684 Negative_regulation of TP53 1 66 0.58 66.09 4.62
112 INT182898 Regulation of Gene_expression of IFN1@ 1 18 0.44 9.49 4.46
113 INT57749 Negative_regulation of Gene_expression of TP53 1 39 0.56 36.79 4.45
114 INT39060 Gene_expression of Mpz 4 45 0.77 21.55 4.3
115 INT72747 Localization of IgG 1 55 0.53 30.88 4.19
116 INT53040 Binding of Agtr1a 7 22 0.47 7.36 4.15
117 INT173910 Gene_expression of LRP2 3 24 0.75 19.99 4.09
118 INT84232 Negative_regulation of Transcription of Fos 1 9 0.58 1.84 3.78
119 INT187819 Regulation of IFN1@ 1 25 0.60 12.89 3.55
120 INT62360 Positive_regulation of PTHLH 1 31 0.70 28.23 3.46
121 INT118270 Regulation of P2RY2 1 16 0.45 7.02 3.45
122 INT176386 Positive_regulation of Gene_expression of TH1L 1 14 0.32 9.17 3.4
123 INT126560 Binding of P2RY2 9 12 0.44 6.43 3.4
124 INT145520 Positive_regulation of Dss1 1 16 0.39 14.04 3.38
125 INT109448 Negative_regulation of MTHFR 3 8 0.58 7.62 3.11
126 INT28094 Binding of PTH 4 29 0.37 13.57 3.09
127 INT158630 Positive_regulation of Positive_regulation of Stat3 1 16 0.49 14.75 3.08
128 INT101477 Binding of ADORA1 1 8 0.31 0.42 3.07
129 INT33237 Regulation of Fst 2 10 0.39 1.3 3
130 INT64437 Gene_expression of IL1R1 1 9 0.65 6.22 2.99
131 INT37363 Localization of PTHLH 1 14 0.68 13.23 2.92
132 INT209033 Positive_regulation of Localization of IFN1@ 1 27 0.67 12.55 2.84
133 INT126966 Positive_regulation of IL1R1 1 8 0.67 6.93 2.84
134 INT184005 Negative_regulation of Gene_expression of Socs3 2 6 0.48 8.76 2.74
135 INT124063 Gene_expression of MTHFR 1 9 0.65 6.22 2.67
136 INT142465 Negative_regulation of Socs3 2 8 0.48 8.31 2.62
137 INT65081 Binding of TPM3 1 9 0.35 0.62 2.58
138 INT64734 Positive_regulation of Mpz 1 17 0.67 6.81 2.55
139 INT37392 Localization of BAS 2 4 0.61 0.96 2.49
140 INT92141 Negative_regulation of CDKN2A 1 53 0.57 44.23 2.48
141 INT63418 Regulation of Agtr1a 1 8 0.44 3.67 2.43
142 INT35359 Negative_regulation of LCT 2 23 0.59 9.13 2.29
143 INT137977 Localization of P2RY2 10 5 0.80 3.07 2.27
144 INT2544 Localization of PTH 2 39 0.81 30.55 2.22
145 INT164248 Positive_regulation of MPZ 4 18 0.67 24.54 2.16
146 INT114330 Binding of MPZ 1 21 0.32 25.58 2.14
147 INT262364 Positive_regulation of LRP2 4 6 0.39 4.44 1.97
148 INT171059 Localization of PDX1 1 8 0.56 6.7 1.9
149 INT56925 Negative_regulation of TSC1 1 54 0.52 63.39 1.87
150 INT21999 Regulation of Gene_expression of IGHG3 1 8 0.30 3.26 1.84
151 INT125820 Localization of TPSD1 1 13 0.70 2.19 1.7
152 INT3343 Regulation of PTH 1 24 0.62 11.18 1.62
153 INT238317 Gene_expression of TRD@ 1 5 0.16 1.65 1.61
154 INT23191 Gene_expression of HDLCQ1 1 13 0.60 14.39 1.58
155 INT105815 Positive_regulation of Gene_expression of P2RY2 1 9 0.50 3.62 1.52
156 INT184032 Regulation of Socs3 1 6 0.37 4.08 1.48
157 INT97560 Regulation of Transcription of Fos 3 6 0.44 2.71 1.46
158 INT53003 Positive_regulation of Positive_regulation of Egr1 1 6 0.64 2.36 1.44
159 INT174814 Localization of IL9 1 7 0.39 2.73 1.4
160 INT155845 Transcription of SOAT1 1 6 0.67 2.89 1.4
161 INT78470 Negative_regulation of Gene_expression of CDKN2A 2 14 0.59 14.44 1.38
162 INT152255 Gene_expression of ATM 1 14 0.71 12.53 1.26
163 INT117719 Transcription of Ephb1 1 2 0.44 0.06 1.25
164 INT107540 Gene_expression of MSD 1 8 0.58 2.54 1.23
165 INT184056 Regulation of Gene_expression of Socs3 1 4 0.45 4.24 1.22
166 INT155846 Transcription of JAK1 1 4 0.67 1.93 1.19
167 INT203646 Gene_expression of STIP1 6 26 0.63 23.57 1.14
168 INT173916 Regulation of LRP2 1 6 0.44 7.96 1.14
169 INT199510 Negative_regulation of STIP1 1 15 0.47 20.99 1.12
170 INT64732 Positive_regulation of Gene_expression of Mpz 2 9 0.50 3.99 1.11
171 INT268379 Gene_expression of ARAF 1 22 0.16 9.34 1.07
172 INT121792 Gene_expression of PTN 1 13 0.75 2.81 1.07
173 INT184020 Localization of Socs3 2 3 0.75 4.05 1.06
174 INT110163 Binding of HLA-DQB1 1 8 0.25 4.71 0.98
175 INT51947 Regulation of Transcription of Egr1 5 2 0.59 0.15 0.96
176 INT114824 Binding of PTHLH 2 12 0.42 9.5 0.9
177 INT65154 Positive_regulation of HLA-DPB1 1 5 0.34 1.37 0.84
178 INT229710 Localization of Agtr1a 6 3 0.60 0.57 0.84
179 INT184026 Binding of Socs3 2 7 0.42 1.93 0.81
180 INT92348 Binding of NPEPPS 1 3 0.04 2.94 0.71
181 INT108968 Regulation of Mpz 4 6 0.54 2.9 0.7
182 INT224579 Gene_expression of Cdkn2d 3 6 0.41 4.23 0.68
183 INT238316 Positive_regulation of Gene_expression of TRD@ 1 2 0.11 0.77 0.64
184 INT170284 Gene_expression of Arsb 1 9 0.65 9.12 0.63
185 INT153699 Regulation of MTHFR 1 2 0.45 1.54 0.63
186 INT301167 Localization of TRD@ 1 1 0.17 1.37 0.59
187 INT161322 Localization of PTEN 1 9 0.73 5.65 0.57
188 INT182810 Gene_expression of Cuzd1 2 5 0.44 1.49 0.53
189 INT182806 Binding of Cuzd1 1 3 0.24 1.45 0.53
190 INT184065 Phosphorylation of Socs3 1 2 0.81 2.67 0.53
191 INT134326 Gene_expression of GSTT2 1 2 0.01 1.61 0.53
192 INT346549 Binding of PTH2R 7 1 0.25 0.88 0.53
193 INT197024 Binding of STIP1 3 11 0.35 10.84 0.52
194 INT346546 Gene_expression of PTH2R 2 1 0.53 1.02 0.49
195 INT346550 Binding of ASPM 1 2 0.07 0.87 0.47
196 INT192808 Negative_regulation of Localization of PTH 2 6 0.59 7.31 0.45
197 INT263204 Transcription of SERPINB1 2 4 0.11 3.09 0.45
198 INT108969 Transcription of Mpz 1 2 0.72 1.26 0.45
199 INT77569 Positive_regulation of PKD1P2 1 6 0.28 1.01 0.4
200 INT144617 Gene_expression of RHO 1 13 0.75 1.74 0.38
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